RAN-aCGH : R GUI Tools for Analysis and Visualization of an Array-CGH Experiment

Abstract

RAN-aCGH is an R GUI tool for the analysis and visualization of array comparative genomic hybridization (array-CGH) experiments. The tool consists of data-loading, preprocessing for missing data, several methods for statistical identification of DNA copy number aberration, and visualization of the copy number change. RAN-aCGH requires a single input format, provides various visualizations, and allows the addition of

a new statistical method, all in a user-friendly graphic user interface (GUI).

Availability: RAN-aCGH (Windows, Mac OS) is freely available for academic researchers. https://sites.google.com/site/computationalbiostatistics/ran-acgh

Supplementary information: Source program, data files, and technical documentation are available at https://sites.google.com/site/computationalbiostatistics/ran-acgh