CODGAS -- Merging MX datasets
This site is the home of CODGAS (Combination Of Datasets by Genetic Algorithm Selection), where you can find a script that demonstrates the concepts describes in Zander et al (Zander et al, 2016). Although originally envisioned for serial datasets (NOT still image datasets but sub-datasets). This software has also been used to merge "Full" datasets to improve for example anomalous signal.
Zander, U., Cianci, M., Foos, N., Silva, C.S., Mazzei, L., Zubieta, C., de Maria, A. & Nanao, M.H. (2016). Acta Cryst.
D72, doi:10.1107/S2059798316012079