Publications

[45] Sim, J; Ryou, B; Choi, M; Lee, C; Park, CM* Org. Lett. 2022, 24, 4264

"Electrochemical C(sp3)–H Functionalization of γ-Lactams Based on Hydrogen Atom Transfer"

[44] Nguyen, NH; Oh, S; Park, CM; Shin, S* Chem. Sci., 2022,13, 1169

"Ortho-selective C–H arylation of phenols with N-carboxyindoles under Brønsted acid- or Cu(I)-catalysis"

[43] Mishra, PK; Kang, M; Lee, H; Kim, S; Choi, S; Sharma, N; Park, CM; Ko, J; Lee, C*; Seo, J*; Rhee, HW* Chem. Sci., 2022, 13, 955

"A chemical tool for blue light-inducible proximity photo-crosslinking in live cells"

[42] Park, M; Park, K; Choi, B; Han, W; Yoon, H; Jung, H; Lee, J; Song, IS; Lim, D; Choi, MK; Lee, YH; Park, CM; Wang, M; Jo, J; Kim, HJ; Kim, S; Schuchman, EH; Jin, HK*; Bae, JS* PNAS 2022, 119, e2115082119

"Discovery of a dual-action small molecule that improves neuropathological features of Alzheimer’s disease mice"

[41] Oh, H; Ryou, B; Park, J; Kim, M; Choi, J; Park, CM* ACS Catal. 2021, 11, 13670

"Synthesis of Bicyclic N-Heterocycles via Photoredox Cycloaddition of Imino-Alkynes and Imino-Alkenes"

[40] Lee, Y; Yu, E; Park, CM* Nature Commun. 2021, 12, 1681

"Programmable site-selective labeling of oligonucleotides based on carbene catalysis"

[39] Bhaskararao, B; Kim, D; Madridejos, JML; Park, CM; Kim, K* J. Mater. Chem. A, 2020, 8, 14671

"Rational design of metal–ligands for the conversion of CH4 and CO2 to acetates: role of acids and Lewis acids"

[38] Choi, S; Oh, H; Sim, J; Yu, E; Shin, S; Park, CM* Org. Lett. 2020, 22, 5528

"Metal-Free Synthesis of Indolopyrans and 2,3-Dihydrofurans Based on Tandem Oxidative Cycloaddition"

[37] Choi, S; Park, J; Yu, E; Sim, J; Park, CM* Angew. Chem. Int. Ed. 2020, 59, 11886 (selected as Hot Paper)

"Electrosynthesis of Dihydropyrano[4,3‐b ]indoles Based on a Double Oxidative [3+3] Cycloaddition"

[36] Ha, S; Lee, Y; Kwak, Y; Mishra, A; Yu, E; Ryou, B; Park, CM* Nature Commun. 2020, 11, 2509

"Alkyne–Alkene [2 + 2] cycloaddition based on visible light photocatalysis"

[35] Lee, J; Han, S; Park, M; Song, I; Choi, M; Yu, E; Park, CM; Kim, H; Kim, S; Schuchman, E; Jin, H;* Bae, JS* Nature Commun. 2020, 11, 2358

"N-AS-triggered SPMs are direct regulators of microglia in a model of Alzheimer’s disease"

[34] Choi, JH; Park, CM* Adv. Synth. Catal. 2018, 360, 3553 (selected as VIP)

“Three‐Component Synthesis of Quinolines based on Radical Cascade Visible‐Light Photoredox Catalysis”

[33] Choi, S†; Ha, S†; Park, CM* ChemComm 2017, 53, 6054 (Feature Article, invited)

“α-Diazo Oxime Ethers for N-Heterocycle Synthesis”

†equal contribution

[32] Ji, Y; Lee, HJ; Kim, M; Nam, G; Lee, SJC; Cho, J; Park, CM* ; Lim, MH* Inorg. Chem. 2017, 56, 6695

“Strategic Design of 2,2’-Bipyridine Derivatives to Modulate Metal–Amyloid-β Aggregation”

[31] Choi, S†; Srinivasulu, V†; Ha, S; Park, CM* ChemComm 2017, 53, 3481

"Synthesis of carbazoles based on gold–copper tandem catalysis"

[30] Loy, NSY; Choi, S; Kim, S; Park, CM* ChemComm 2016, 52, 7336 (cover article)

"The synthesis of pyrroles and oxazoles based on gold α-imino carbene complexes"

[29] Loy, NSY; Kim, S; Park, CM* Org. Lett. 2015, 17, 395

"Synthesis of Unsymmetrical Pyrazines Based on α-Diazo Oxime Ethers"

[28] Jiang, Y; Park, CM* ; Loh, TP* Org. Lett. 2014, 16, 3432

“Transition Metal-Free Synthesis of Substituted Pyridines via Ring-expansion of 2-Allyl-2H-Azirines"

[27] Jiang, Y; Park, CM* Chem. Sci. 2014, 5, 2347

“Catalyst-Controlled Selective Synthesis of Pyridines and Pyrroles“

[26] Souers, AJ*; Leverson, JD; Boghaert, ER; Ackler, SL; Catron, ND; Chen, J; Dayton, BD; Ding, H; Enschede, SH; Fairbrother, WJ; Huang, DCS; Hymowitz, SG; Jin, S; Khaw, SL; Kovar, PJ; Lam, LT; Lee, J; Maecker, HL; Marsh, KC; Mason, KD; Mitten, MJ; Nimmer, PM; Oleksijew, A; Park, CH; Park, CM; Phillips, DC; Roberts, AW; Sampath, D; Seymour, JF; Smith, ML; Sullivan, GM; Tahir, SK; Tse, C; Wendt, MD; Xiao, Y; Xue, JC; Zhang, H; Humerickhouse, RA; Rosenberg, SH; Elmore, SW Nature Medicine 2013, 19, 202

“ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets”

[25] Loy, SYN; Singh, A; Xu, X; Park, CM* Angew. Chem. Int. Ed. 2013, 52, 2212

“Synthesis of Pyridines via Carbenoid-mediated Ring Opening of 2H-Azirines”

[24] Qi, X; Dai, L; Park, CM* ChemComm 2012, 48, 11244

“Carbenoid-mediated N-O Bond Insertion and Its Application in the Synthesis of Pyridines“

Graphical abstract: Carbenoid-mediated N–O bond insertion and its application in the synthesis of pyridines

[23] Xu, X†; Liu, Y†; Park, CM* Angew. Chem. Int. Ed. 2012, 51, 9372

“Rhodium(III)-catalyzed Intramolecular Annulation via C-H Activation: Total Synthesis of (±)-antofine, (±)-septicine, (±)-tylophorine, and rosettacin”

[22] Qi, X; Xu, X; Park, CM* ChemComm 2012, 48,3996

“Facile Synthesis of 2-Alkyl/Aryloxy-2H-azirines and Their Application in the Synthesis of Pyrroles” .

Graphical abstract: Facile synthesis of 2-alkyl/aryloxy-2H-azirines and their application in the synthesis of pyrroles

[21] Jiang, Y; Chan, WC; Park, CM* J. Am. Chem. Soc. 2012, 134, 4104 (highlighted in Synfacts 08/12)

“Expedient Synthesis of Highly Substituted Pyrroles via Tandem Reaction of α-Diazo Oxime Ethers”

Abstract Image

[20] Jiang, Y; Khong, VZY; Lourdusamy, E; Park, CM* ChemComm 2012, 48, 3133

“Synthesis of 2-Aminofurans and 2-Unsubstituted Furans via Carbenoid-mediated [3+2] Cycloaddition”

Graphical abstract: Synthesis of 2-aminofurans and 2-unsubstituted furans via carbenoid-mediated [3 + 2] cycloaddition

[19] Liu, Y; Li, D; Park, CM* Angew. Chem. Int. Ed. 2011, 50, 7333

“Stereoselective Synthesis of Highly Substituted Enamides via Oxidative Heck Reactions“

[18] Qi, X†; Jiang, Y†; Park, CM* ChemComm 2011, 47, 7848

“Divergent Reactivity of α-Oximino Carbenoids: Facile Access to 2-Isoxazolines and 2H-Azirines“

[17] Lourdusamy, E; Yao, L; Park, CM* Angew. Chem. Int. Ed. 2010, 49, 7963 (highlighted in Synfacts 01/11)

“Stereoselective Synthesis of a-Diazo Oxime Ethers and Their Application in the Synthesis of Highly Substituted Pyrroles via [3+2] Cycloaddition”

[16] Bruncko, M*; Tahir, SK; Song, X; Chen, J; Ding, H; Huth, JR; Jin, S; Judge, RA; Madar, DJ; Park, CH; Park, CM; Petros, AM; Tse, C; Rosenberg, SH; Elmore, SW Bioorg. Med.Chem.Lett. 2010, 20, 7503

“N-Aryl-benzimidazolones as novel small molecule HSP90 inhibitors”

Full-size image (59 K)

[15] Petros, AM; Huth, JR; Oost, T; Park, CM; Ding, H; Wang, XL; Zhang, HC; Nimmer, P; Mendoza, R; Sun, CH; Mack, J; Walter, K; Dorwin, S; Gramling, E; Ladror, U; Rosenberg, SH; Elmore, SW; Fesik, SW; Hajduk, PJ* Bioorg. Med.Chem. Lett. 2010, 20, 6587

“Discovery of a potent and selective Bcl-2 inhibitor using SAR by NMR”

Full-size image (28 K)

[14] Park, CM; Bruncko, M; Adickes, J; Bauch, J; Ding, H; Kunzer, A; Marsh, KC; Nimmer, P; Shoemaker, AR; Song, X; Tahir, SK; Wang, X; Wendt, MD; Yang, X; Zhang, H; Fesik, S; Rosenberg, SH; Elmore, SW* J. Med. Chem. 2008, 51, 6902

“Discovery of an Orally Bioavailable Small Molecule Inhibitor of Pro-survival B-cell Lymphoma 2 Proteins”

Abstract Image

[13] Bruncko, M; Oost, TK; Belli, BA; Ding, H; Joseph, MK; Kunzer, A; Martineau, D; McClellan, WJ; Mitten, M; Ng, SC; Nimmer, PM; Oltersdorf, T; Park, CM; Petros, AM; Shoemaker, AR; Song, X; Wang, X; Wendt, MD; Zhang, H; Fesik, SW; Rosenberg, SH; Elmore, SW* J. Med. Chem. 2007, 50, 641

“Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-XL”

Abstract Image

[12] Park, CM*; Oie, T; Petros, AM; Zhang, H; Nimmer, PM; Henry, RF; Elmore, SW J. Am. Chem. Soc. 2006, 128, 16206

“Design, Synthesis and Computational Studies of Inhibitors of Bcl Protein”

Abstract Image

[11] Park, CM* J. Org. Chem. 2006, 71, 413

“Concise Synthesis of 3,7-Dioxa-9-aza-bicyclo[3,3,1]-nonane”

Abstract Image

[10] Park, CM*; Sun, C; Olejniczak, ET; Wilson, AE; Meadows, RP; Betz, SF; Elmore, SW; Fesik, SW Bioorg. Med.Chem.Lett. 2005, 15, 771

“Non-peptidic small molecule inhibitors of XIAP”

[9] Elmore, SW; Oost, T; Park, CM Annual Reports in Medicinal Chemistry 2005, 40, 245

“Inhibitors of Anti-apoptotic Proteins for Cancer Therapy”

[8] Wender, PA*; Lippa, B; Park, CM; Irie, K; Nakahara, A; Ohigashi, H Bioorg. Med.Chem. Lett. 1999, 9, 1687

“Selective Binding of Bryostatin Analogues to the Cysteine Rich Domains of Protein Kinase C Isozymes”

[7] Wender, PA*; Brabander, JD; Harran, PG; Jimenez, JM; Koehler, MFT; Lippa, B; Park, CM; Shiozaki, M J. Am. Chem. Soc. 1998, 120, 4534

“Synthesis of the First Members of a New Class of Biologically Active Bryostatin Analogues”

[6] Wender, PA*; Martin-Cantalejo, Y; Carpenter, AJ; Chiu, A; Brabander, JD; Harran, PG; Jimenez, JM; Koehler, MFT; Lippa, B; Morrison, JA; Muller, SG; Muller, SN; Park, CM; Shiozaki, M; Siedenbiedel, C; Skalitzky, DJ; Tanaka, M; Irie, K Pure Appl. Chem. 1998, 70, 539

“The chemistry-medicine continuum: synthetic, computer, spectroscopic and biological studies on new chemotherapeutic leads”

[5] Wender, PA*; Brabander, JD; Harran, PG; Jimenez, JM; Koehler, MFT; Lippa, B; Park, CM; Siedenbiedel, C Proc. Natl. Acad.Sci. USA 1998, 95, 6624

“The design, computer modeling, solution structure, and biological evaluation of synthetic analogs of bryostatin 1”

[4] Lee, E*; Park, CM; Yoon, JS J. Am. Chem. Soc. 1995, 117, 8017

"Total Synthesis of Dactomelynes"

[3] Lee, E*; Park, CM J. Chem. Soc., Chem. Commun. 1994, 293

"C-Furanoside Synthesis via Radical Cyclization of b-Alkoxyacrylates"

[2] Lee, E*; Tae, JS; Lee, C; Park, CM Tetrahedron Lett. 1993, 34, 4831

"b-Alkoxyacrylates in Radical Cyclizations: Remarkably Efficient Oxacycle Synthesis"

[1] Lee, E*; Hur, CU; Park, CM Tetrahedron Lett. 1990, 31, 5039

"Synthesis of a-Methylene d-valerolactones and a-Methylenecyclohexanones via Radical Cyclization of Propiolates and Acetylenic Ketones"