Professor

https://sites.google.com/site/chanseokshinlab/professor/2017신찬석4(3.5x4.5).jpg

Chanseok Shin, Ph.D. Position : Professor

Address : Seoul National University, Department of Agricultural Biotechnology,

1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea

Phone : +82-2-880-4643

Fax : +82-2-873-3112

E-mail : cshin@snu.ac.kr

Education

1987 - 1991 B. S. in Agricultural Chemistry, Seoul National University, Republic of Korea

1991 - 1995 M. S. in Agricultural Chemistry, Seoul National University, Republic of Korea

1997 - 2004 Ph. D. in Biological Sciences, Columbia University, New York, USA

Professional Experience

2004. Postdoctoral Research Associate, Columbia University, New York, USA

2004 - 2009. Postdoctoral Research Fellow, Whitehead Institute for Biomedical Research, Cambridge, MA, USA

2009 - present. Assistant Professor, Associate Professor, Professor, Department of Agricultural Biotechnology, Seoul National University, Republic of Korea


Fellowships and Awards

2003. John S. Newberry Prize, Department of Biological Sciences, Columbia University, New York, USA

2005 - 2008. Damon Runyon Fellow, USA

Publications

Shin, C. (2008) Cleavage of the star strand facilitates assembly of some microRNAs into Ago2-containing silencing complexes in mammals. Mol. Cells 26, 308 - 313.

Baek, D.*, Villen, D.*, Shin, C.*, Camargo, F. D., Gygi, S. P., and Bartel, D. P. (2008) The impact of microRNAs on protein output. Nature 455, 64 - 71. *equal contribution

Marin-Vinader, L., Shin, C., Onnekink, C., Manley, J. L., and Lubsen, N. H. (2006) Hsp27 enhances recovery of splicing as well as rephosphorylation of SRp38 after heat shock. Mol. Biol. Cell 17, 886 - 894.

Matranga, C., Tomari, Y., Shin, C., Bartel, D. P., and Zamore, P. D. (2005) Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes. Cell 123, 607 - 620.

Shin, C., Kleiman, F. E., and Manley, J. L. (2005) Multiple properties of the splicing repressor SRp38 distinguish it from typical SR proteins. Mol. Cell. Biol. 25, 8334 - 8343.

Shin, C. and Manley, J. L. (2004) Cell signalling and the control of pre-mRNA splicing. Nature Rev. Mol. Cell. Biol. 5, 727 - 738.

Shin, C., Feng, Y., and Manley, J. L. (2004) Dephosphorylated SRp38 acts as a splicing repressor in response to heat shock. Nature 427, 533 - 558.

Shin, C. and Manley, J. L. (2003) Role of alternative splicing during the cell cycle and programmed cell death. Handbook of Cell Signaling 3, 331 - 334.

Shin, C. and Manley, J. L. (2002) The SR proein SRp38 represses splicing in M phase cells. Cell 111, 407 - 417.

Lim, J. Y., Shin, C., Chung, E. J., Kim, J. S., Kim, H. U., Oh, S. J., Choi, W. B., Ryou, C. S., Kim, J. B., Kwon, M. S., Chung, Y. T., Song, S. I., Kim, J. K., Nahm, B. H., Hwang, Y. S., Eun, M. Y., Lee, J. S., Cheong, J. J., and Choi, Y. D. (2000) Analysis of expressed sequence tags from Brassica rapa L. ssp. Pekineses. Mol. Cells 10, 399 - 404.

Shin, C., Choi, J. N., Song, S. I., Song, J. T., Ahn, J. H., Lee, J. S., and Choi, Y. D. (1996) Loop B domain of hairpin ribozyme is physically separable from loop A domain. Nucleic Acids Res. 24, 2685 - 2689.

Shin, C., Choi, J. N., Song, S. I., Song, J. T., Ahn, J. H., Lee, J. S., and Choi, Y. D. (1996) Site-specific cleavage of garlic latent virus RNA by hairpin ribozyme. Mol. Cells 6, 209 - 214.