Professor
Chanseok Shin, Ph.D. Position : Professor
Address : Seoul National University, Department of Agricultural Biotechnology,
1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea
Phone : +82-2-880-4643
Fax : +82-2-873-3112
E-mail : cshin@snu.ac.kr
Education
1987 - 1991 B. S. in Agricultural Chemistry, Seoul National University, Republic of Korea
1991 - 1995 M. S. in Agricultural Chemistry, Seoul National University, Republic of Korea
1997 - 2004 Ph. D. in Biological Sciences, Columbia University, New York, USA
Professional Experience
2004. Postdoctoral Research Associate, Columbia University, New York, USA
2004 - 2009. Postdoctoral Research Fellow, Whitehead Institute for Biomedical Research, Cambridge, MA, USA
2009 - present. Assistant Professor, Associate Professor, Professor, Department of Agricultural Biotechnology, Seoul National University, Republic of Korea
Fellowships and Awards
2003. John S. Newberry Prize, Department of Biological Sciences, Columbia University, New York, USA
2005 - 2008. Damon Runyon Fellow, USA
Publications
Shin, C. (2008) Cleavage of the star strand facilitates assembly of some microRNAs into Ago2-containing silencing complexes in mammals. Mol. Cells 26, 308 - 313.
Baek, D.*, Villen, D.*, Shin, C.*, Camargo, F. D., Gygi, S. P., and Bartel, D. P. (2008) The impact of microRNAs on protein output. Nature 455, 64 - 71. *equal contribution
Marin-Vinader, L., Shin, C., Onnekink, C., Manley, J. L., and Lubsen, N. H. (2006) Hsp27 enhances recovery of splicing as well as rephosphorylation of SRp38 after heat shock. Mol. Biol. Cell 17, 886 - 894.
Matranga, C., Tomari, Y., Shin, C., Bartel, D. P., and Zamore, P. D. (2005) Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes. Cell 123, 607 - 620.
Shin, C., Kleiman, F. E., and Manley, J. L. (2005) Multiple properties of the splicing repressor SRp38 distinguish it from typical SR proteins. Mol. Cell. Biol. 25, 8334 - 8343.
Shin, C. and Manley, J. L. (2004) Cell signalling and the control of pre-mRNA splicing. Nature Rev. Mol. Cell. Biol. 5, 727 - 738.
Shin, C., Feng, Y., and Manley, J. L. (2004) Dephosphorylated SRp38 acts as a splicing repressor in response to heat shock. Nature 427, 533 - 558.
Shin, C. and Manley, J. L. (2003) Role of alternative splicing during the cell cycle and programmed cell death. Handbook of Cell Signaling 3, 331 - 334.
Shin, C. and Manley, J. L. (2002) The SR proein SRp38 represses splicing in M phase cells. Cell 111, 407 - 417.
Lim, J. Y., Shin, C., Chung, E. J., Kim, J. S., Kim, H. U., Oh, S. J., Choi, W. B., Ryou, C. S., Kim, J. B., Kwon, M. S., Chung, Y. T., Song, S. I., Kim, J. K., Nahm, B. H., Hwang, Y. S., Eun, M. Y., Lee, J. S., Cheong, J. J., and Choi, Y. D. (2000) Analysis of expressed sequence tags from Brassica rapa L. ssp. Pekineses. Mol. Cells 10, 399 - 404.
Shin, C., Choi, J. N., Song, S. I., Song, J. T., Ahn, J. H., Lee, J. S., and Choi, Y. D. (1996) Loop B domain of hairpin ribozyme is physically separable from loop A domain. Nucleic Acids Res. 24, 2685 - 2689.
Shin, C., Choi, J. N., Song, S. I., Song, J. T., Ahn, J. H., Lee, J. S., and Choi, Y. D. (1996) Site-specific cleavage of garlic latent virus RNA by hairpin ribozyme. Mol. Cells 6, 209 - 214.