Metabolomics

The Cooper lab started a new venture in large-scale, non-targeted metabolomics in 2022 with the acquisition of an Exploris 240 mass spectrometer.   This technology will be used to identify compounds in plants that confer disease resistance and to determine how plant disease resistance compounds alter the metabolisms of plant pathogens.  Coupled with proteomics  data, metabolomics data will help extend biological systems information.

Papers:

An assessment of AcquireX and Compound Discoverer software 3.3 for non-targeted metabolomics (2024). Bret Cooper and Ronghui Yang. Scientific Reports 14, 4841.  DOI: 10.1038/s41598-024-55356-3

Disruptive Effects of Resveratrol on a Bacterial Pathogen of Beans (2023). Bret Cooper. Journal of Proteome Research 22, 204-214.  Published on-line before print December 13, 2022.  DOI: 10.1021/acs.jproteome.2c00633 

The Detriment of Salicylic Acid to the Pseudomonas savastanoi pv. phaseolicola Proteome (2022).  Bret Cooper.  Molecular Plant-Microbe Interactions 9, 814-824.  Published on-line before print May 25, 2022.  DOI: 10.1094/MPMI-05-22-0104-R 

Salicylic Acid and Phytoalexin Induction by a Bacterium that Causes Halo Blight in Beans (2022).  Bret Cooper, Kimberly B. Campbell, and Wesley M. Garrett.  Phytopathology 112, 1766-1775. Published on-line before print February 11, 2022. DOI: 10.1094/PHYTO-12-21-0496-R 

Bacterial Immobilization and Toxicity Induced by a Bean Plant Immune System (2021). Bret Cooper, Hunter S. Beard, Ronghui Yang, Wesley M. Garrett, and Kimberly B. Campbell. Journal of Proteome Research 20, 3664-3677. DOI: 10.1021/acs.jproteome.1c00232

Benzothiadiazole Conditions the Bean Proteome for Immunity to Bean Rust (2020). Bret Cooper, Hunter Beard, Wesley M. Garrett, and Kimberly B. Campbell.  Molecular Plant-Microbe Interactions.  Published on-line before print January 30, 2020. DOI: 10.1094/MPMI-09-19-0250-R