personal
My interests: Spectroscopic characterization of proteins and their structure function relationships. Computational approaches to protein structure and function, Molecular Dynamics and docking.
My pubblications
2015
Rotili, D.; De Luca, A.; Tarantino, D.; Pezzola, S.; Forgione, M.; Morozzo della Rocca, B.; Falconi, M.; Mai, A.; Caccuri, A. Maria Synthesis and structure--activity relationship of new cytotoxic agents targeting human glutathione-S-transferases. Eur J Med Chem 2015, 89, 156-71.
2013
Tesauro, C.; Morozzo della Rocca, B.; Ottaviani, A.; Coletta, A.; Zuccaro, L.; Arnò, B.; D'Annessa, I.; Fiorani, P.; Desideri, A. Molecular mechanism of the camptothecin resistance of Glu710Gly topoisomerase IB mutant analyzed in vitro and in silico. Mol Cancer 2013, 12, 100.
2011
Vassallo, O.; Castelli, S.; D'Annessa, I.; Morozzo della Rocca, B.; Stella, L.; Knudsen, B. R.; Desideri, A. Evidences of a natively unfolded state for the human topoisomerase IB N-terminal domain. Amino acids 2011, 41, 945-53.
Di Marino, D.; Oteri, F.; Morozzo della Rocca, B.; D'Annessa, I.; Falconi, M. Mapping multiple potential ATP binding sites on the matrix side of the bovine ADP/ATP carrier by the combined use of MD simulation and docking. Journal of molecular modeling 2011.
Galbiati, A.; Morozzo della Rocca, B.; Tabolacci, C.; Beninati, S.; Desideri, A.; Paradossi, G. PVA engineered microcapsules for targeted delivery of camptothecin to HeLa cells. Materials Science and Engineering: C2011, 31, 1653 - 1659.
Galbiati, A.; Tabolacci, C.; Morozzo della Rocca, B.; Mattioli, P.; Beninati, S.; Paradossi, G.; Desideri, A. Targeting tumor cells through chitosan-folate modified microcapsules loaded with camptothecin. Bioconjugate chemistry 2011, 22, 1066-72.
2010
Di Marino, D.; Oteri, F.; Morozzo della Rocca, B.; Chillemi, G.; Falconi, M. ADP/ATP mitochondrial carrier MD simulations to shed light on the structural-dynamical events that, after an additional mutation, restore the function in a pathological single mutant. Journal of structural biology 2010, 172, 225-32.
Morozzo della Rocca, B.; Smith, C. I.; Tesauro, C.; Desideri, A.; Weightman, P. Adsorption of the cysteine–tryptophan dipeptide at the Au(110)/liquid interface studied using reflection anisotropy spectroscopy. Surface Science 2010, 604, 2170 - 2176.
Coletta, A.; Morozzo della Rocca, B.; Jaisankar, P.; Majumder, H. K.; Chillemi, G.; Sanna, N.; Desideri, A. Assignment of UV-vis spectrum of (3,3')-diindolylmethane, a Leishmania donovani topoisomerase IB inhibitor and a candidate DNA minor groove binder. The journal of physical chemistry. A 2010, 114, 7121-6.
2008
Lauria, G.; Sanchez, P.; Morozzo della Rocca, B.; Pierri, C. L.; Polizio, F.; Stipani, I.; Desideri, A. Structural-dynamical properties of the transmembrane segment VI of the mitochondrial oxoglutarate carrier studied by site directed spin-labeling. Molecular membrane biology 2008, 25, 236-44.
2006
Falconi, M.; Chillemi, G.; Di Marino, D.; D'Annessa, I.; Morozzo della Rocca, B.; Palmieri, L.; Desideri, A. Structural dynamics of the mitochondrial ADP/ATP carrier revealed by molecular dynamics simulation studies.Proteins 2006, 65, 681-91.
2005
Morozzo della Rocca, B.; Miniero, D. V.; Tasco, G.; Dolce, V.; Falconi, M.; Ludovico, A.; Cappello, A. R.; Sanchez, P.; Stipani, I.; Casadio, R.; Desideri, A.; Palmieri, F. Substrate-induced conformational changes of the mitochondrial oxoglutarate carrier: a spectroscopic and molecular modelling study. Molecular membrane biology 2005, 22, 443-52.
2003
Cioni, P.; Pesce, A.; Morozzo della Rocca, B.; Castelli, S.; Falconi, M.; Parrilli, L.; Bolognesi, M.; Strambini, G. B.; Desideri, A. Active-site copper and zinc ions modulate the quaternary structure of prokaryotic Cu,Zn superoxide dismutase. Journal of molecular biology 2003, 326, 1351-60.
Morozzo della Rocca, B.; Lauria, G.; Venerini, F.; Palmieri, L.; Polizio, F.; Capobianco, L.; Stipani, V.; Pedersen, J. Z.; Cappello, A. R.; Desideri, A.; Palmieri, F. The mitochondrial oxoglutarate carrier: structural and dynamic properties of transmembrane segment IV studied by site-directed spin labeling. Biochemistry 2003, 42, 5493-9.