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I joined the Biomechanics and Bioengineering laboratory (BMBI) in October 2015 as CNRS Researcher, where I started a new topic of research on “Targeted drug delivery with bio-artificial capsules”. My principal research activity is focused on studying the physics of complex fluids, soft matter and biomedical systems. In particular, I am interested in phenomena occurring at the microscopic scale and involving fluid-structure interaction, mass and/or heat transfer. I am using and constantly developing state-of-the-art numerical methods to perform multi-physics computer simulations. I am interested in problems involving interactions between different components of a given system, for which I study the complex dynamical behavior while tracking the nonlinear causes and effects relationship between its different components.
Drug release from a capsule subjected to shear flow
The simulation allows for analyzing the spatial distribution of the released drug molecules and the flow developed around the capsule.
Spheroid trapped by a well of a microfluidic organ-on-chip
The simulation predicts the dynamics of the spheroid under flow within the well, as well as the spatial distribution of the secreted insulin.
Opening a bicuspid lymphatic valve under flow
The simulation allows for analyzing the spatial distribution of wall shear stress on the surface of one of the valve’s leaflets.
Research areas
Biophysics
Soft matter / Complex fluids
Transport phenomena
Phase-transitions
Micro-fluidic
Multi-physics computer simulations
Studied problems and phenomena
Drug delivery (controlled and targeted drug delivery using capsules and liposomes), see these slides and watch this talk
Dynamics and rheology of fluid-filled soft particles (capsules, vesicles, blood cells), see these slides
The lymph pumping mechanism in the lymphatic system
Nanoparticles (nanofluids, stability of liquid-liquid interfaces)
Pattern formation (tumor growth, wrinkles, dendrites)
For more information, please visit my publications page
Numerical and computational methods
Lattice-Boltzmann Method (LBM)
Immersed Boundary Method (IBM)
Boundary Integral Method (BIM)
Phase-field Method (PFM)
Fluid-Structure Interaction (FSI)
Computational Fluid Dynamics (CFD): Multi-component/multi-phase fluid flow
High Performance Computing (HPC)
Funded projects
PhD financial support - Région Hauts-de-France to recruit a PhD student (2025) / (Grant ALRC2.0-001942)
HPC resources from GENCI-IDRIS (Grant 2024-[AD012A13687R2])
Partner PI of ANR PRC 550 745.13 € (2024-2028): SOCA - Suspensions of SOtf Capsules (ANR-24-CE06-6245-02)
WP PI of ANR PRC 721 628 € (2023-2027): UC-DC - Ultrasonic-Controlled delivery from Drug Carriers (ANR-23-CE51-0057)
PI of ANR JCJC 147 096 € (2021 - 2024): MechLymph - Biomechanics and Mechanobiology of the Lymphatic System (ANR-20-CE45-0008)
6 months grant - Labex MS2T to recruit MSc students (2017, 2020, 2021, 2022)
6 months grant - BMBI laboratory to recruit MSc students (2018, 2020, 2021,2024)
UTC Research Mobility: 5 000 € (2019)
PhD financial support - MESRI to recruit a PhD student (2018)
Partner of CapsAntiOx - Région Picardie: Projet de Recherche Structurant (2016-2020)
Partner of B3Caps - Sorbonne Université: Emergence (2015 - 2016)
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