Develop multiscale mathematical and computational models to enhance understanding of the mechanisms governing tissue remodeling and damage as a result of diseases and infections
Simulate the treatment of those conditions to improve human health
Specialities & Methods
Modeling kinetics and transport processes involved in biological and chemical interactions related to both physiological microenvironments and engineered biomedical and pharmaceutical systems, particularly those involved in tissue damage and treatment
Building continuous PDE or ODE-based mathematical models and/or discrete agent-based computational models
a) for transport of biochemicals through heterogeneous porous materials—primarily extracellular matrices—that change morphology dynamically due to the influence of chemical reactions and
b) for dynamic, complex biological systems involving chemical, physical, and biological interactions of diverse, heterogeneous cell populations with these materials and the chemical species in tissue microenvironments.