Publications

2019

Diabetic endothelial colony forming cells have the potential for restoration with glycomimetics

A pivotal role for Nrf2 in endothelial detachment– implications for endothelial erosion of stenotic plaques

2018

The Interplay of SIRT1 and Wnt Signaling in Vascular Calcification

QRISK3 improves detection of cardiovascular disease risk in patients with systemic lupus erythematosus

Endothelial Progenitor Cells: New Targets for Therapeutics for Inflammatory Conditions With High Cardiovascular Risk

2017

Macrophage enzyme and reduced inflammation drive brain correction of mucopolysaccharidosis IIIB by stem cell gene therapy

Endothelial microparticles prevent lipid-induced endothelial damage via Akt/eNOS signaling and reduced oxidative stress

2016

Age and Smoking Related Changes in Metal Ion Levels in Human Lens: Implications for Cataract Formation

2015

Complementing the sugar code: role of GAGs and sialic acid in complement regulation

Neuroinflammation, mitochondrial defects and neurodegeneration in mucopolysaccharidosis III type C mouse model

2014

The Role of Complement in Age-Related Macular Degeneration: Heparan Sulphate, a ZIP Code for Complement Factor H?

2013

Signal one and two blockade are both critical for non-myeloablative murine HSCT across a major histocompatibility complex barrier

Myeloid/Microglial driven autologus hematopoetic stem cell gene therapy corrects a neuronopatic lysosomal disease

2012

Hematopoietic stem cell and gene therapy corrects primary neuropathology and behavior in mucopolysaccharidosis IIIA mice

Neuropathology in Mouse Models of Mucopolysaccharidosis Type I, IIIA and IIIB

PhD Thesis: Lentiviral Vector Mediated Haematopoietic Stem Cell Gene Therapy For Mucopolysaccharidosis Type IIIA

2011

Female Mucopolysaccharidosis IIIA Mice Exhibit Hyperactivity and a Reduced Sense of Danger in the Open Field Test

Hyperactive behaviour in the mouse model of mucopolysaccharidosis IIIB in the open field and home cage environments

2010

Genistein improves neuropathology and corrects behaviour in a mouse model of neurodegenerative metabolic disease