PhD Thesis: Link

International peer review journal:

(15) « Interplay between VSD, pore and membrane lipids in electromechanical coupling in HCN channels »

Ahmad Elbahnsi*, John Cowgill*,  Verena Burtscher,  Linda Wedemann, Luise Zeckey,  Baron Chanda and Lucie Delemotte

ELife (2023). LINK

(14) « Ivacaftor-Mediated Potentiation of ABCB4 Missense Mutations Affecting Critical Motifs of the NBDs: Repositioning Perspectives for Hepatobiliary Diseases »

Jean-Louis Delaunay, Ahmad Elbahnsi, Alix Bruneau, Claire Madry, Anne-Marie Durand-Schneider, Anne Stary, Chantal Housset, Jérémie Gautheron, Isabelle Callebaut and Tounsia Aït-Slimane.

Int J Mol Sci. (2023)

(13) « Acting on the CFTR Membrane-Spanning Domains Interface Rescues Some Misfolded Mutants »

Baatallah N*, Elbahnsi A*, Chevalier B, Castanier S, Mornon JP, Pranke I, Edelman A, Sermet-Gaudelus I, Callebaut I and Hinzpeter A.

Int J Mol Sci. (2022)

(12) « Probing effects of the SARS-CoV-2 E protein on membrane curvature and intracellular calcium »

A. Mehregan, S. Pérez-Conesa, Y. Zhuang, A. Elbahnsi, D. Pasini, E. Lindahl, R. J Howard, C. Ulens and L. Delemotte. 

Biochim Biophys Acta Biomembr. (2022)

(11) « Pharmacological chaperones improve intra-domain stability and inter-domain assembly via distinct binding sites to rescue misfolded CFTR »

N. Baatallah*, A. Elbahnsi*, J-P. Mornon, B. Chevalier, I. Pranke, N. Servel, R. Zelli, J-L. Décout, A. Edelman, I. Sermet- Gaudelus, I. Callebaut and A.Hinzpeter. 

Cell. Mol. Life Sci. (2021)

(10) « Insights into the Role of the Discontinuous TM7 Helix of Human Ferroportin through the Prism of the Asp325 Residue »

Marlène Le Tertre*, Ahmad Elbahnsi*, Chandran Ka, Isabelle Callebaut and Gérald Le Gac

Int. J. Mol. Sci. (2021). Link

(9) « Structure and sequence-based computational approaches to allosteric signal transduction: application to electromechanical coupling in voltage-gated ion channels »

Ahmad Elbahnsi and Lucie Delemotte.

JMB (2021). Link

(8) « New insights into structure and function of bis-phosphinic acid derivatives and implications for CFTR modulation »

Bitam Sara*, Elbahnsi Ahmad*, Creste Geordie*, Pranke Iwona, Chevalier Benoit, Berhal Farouk, Hoffmann Brice, Servel Nathalie, Tondelier Danielle, Hatton Aurelie, Moquereau Christelle, Faria Da Cunha Mélanie, Lepissier Agathe, Hinzpeter Alexandre, Mornon Jean-Paul, Prestat Guillaume, Edelman Aleksander, Callebaut Isabelle, Gravier-Pelletier Christine, Sermet-Gaudelus Isabelle

Scientific Reports (2021). Link 

(7) « A dynamic view of DNA structure within the nucleosome: biological implications »

Romain Retureau*, Nicolas Foloppe, Ahmad Elbahnsi,  Christophe Oguey and Brigitte Hartmann

JSB (2020). Link

(6) « Functional and pharmacological characterization of the rare CFTR mutation W361R »

Arnaud Billet*, Ahmad Elbahnsi, Mathilde Jollivet-Souchet, Brice Hoffmann, Jean-Paul Mornon, Isabelle Callebaut and Frederic Becq

Front. Pharmacol. (2020). Link

(5) « Targeting different binding sites in the CFTR structures allows to synergistically potentiate channel activity »

Lionel Froux*, Ahmad Elbahnsi*, Benjamin Boucherle*, Arnaud Billet, Nesrine Baatallah, Brice Hoffmann, Julien Alliot, Renaud Zelli, Wael Zeinyeh, Romain Haudecoeur, Benoit Chevalier, Antoine Fortuné, Sandra Mirval, Christophe Simard, Pierre Lehn, Jean-Paul Mornon, Alexandre Hinzpeter, Frédéric Becq, Isabelle Callebaut and Jean-Luc Décout

Eur. J. Med. Chem. (2020). Link

(4) « Molecular model of the ferroportin intracellular gate and implications for the human iron transport cycle and hemochromatosis type 4A »

Julie Guellec*, Ahmad Elbahnsi, Marlène Le Tertre, Kévin Uguen, Isabelle Gourlaouen, Claude Férec, Chandran Ka, Isabelle Callebaut and Gérald Le Gac

Faseb (2019). Link

(3) « Combining theoretical and experimental data to decipher CFTR 3D structures and functions »

Brice Hoffmann*, Ahmad Elbahnsi*, Pierre Lehn, Jean-Luc Décout, Fabio Pietrucci, Jean-Paul Mornon and Isabelle Callebaut.

Cell. Mol. Life Sci. (2018). Link

(2) « Holding the nucleosome together: A quantitative description of the DNA-histone interface in solution »

Ahmad Elbahnsi*, Romain Retureau*, Marc Baaden, Brigitte Hartmann and Christophe Oguey.

J. Chem. Theory Comput. (2017). Link

(1) « Simulations meet experiment to reveal new insights into DNA intrinsic mechanics »

Akli Ben Imeddourene*, Ahmad Elbahnsi, Marc Guéroult, Christophe Oguey, Nicolas Foloppe and Brigitte Hartmann.

Plos Comp. Biol. (2015). Link

*first author(s) / equal contribution

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PREPRINTS:

(3) « Interplay between VSD, pore and membrane lipids in electromechanical coupling in HCN channels »

Ahmad Elbahnsi, John Cowgill,  Verena Burtscher,  Linda Wedemann, Luise Zeckey,  Baron Chanda and Lucie Delemotte

bioRxiv (2022). LINK 

(2) « Biophysical characterization of the SARS-CoV-2 E protein »

Aujan Mehregan, Sergio Pérez-Conesa, Yuxuan Zhuang, Ahmad Elbahnsi, Diletta Pasini, Erik Lindahl, Rebecca J Howard, Chris Ulens and Lucie Delemotte

bioRxiv (2021). LINK 

(1) CFTR corrector efficacy is associated with occupancy of distinct binding sites

Nesrine Baatallah*, Ahmad Elbahnsi*, Jean-Paul Mornon, Benoit Chevalier, Iwona Pranke, Nathalie Servel, Renaud Zelli, Jean-Luc Décout, Aleksander Edelman, Isabelle Sermet-Gaudelus, Isabelle Callebaut and Alexandre Hinzpeter

bioRxiv (2021). LINK

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Conference proceedings:

(9) « Haemochromatosis type 4: structure/function analysis of the newly identified p. Ser47Phe missense mutation provides new insights about the ferroportin biology and mechanisms of disease »

Kévin Uguen, Marlène Le Tertre, Ahmad Elbahnsi, Chandran Ka, Isabelle Gourlaouen, Claude Férec, Isabelle Callebaut, Gérald Le Gac

EUROPEAN JOURNAL OF HUMAN GENETICS, SWEDEN. October 2019.

(8) « The structure-function analysis of ferroportin 1 (FPN1) gating residues sheds new light on the pathogenic mechanisms involved in haemochromatosis type 4A (HC 4A) »

Marlène Le Tertre*, Ahmad Elbahnsi, Cécile Ged, Chandran Ka, Kévin Uguen, Julie Guellec, Isabelle Gourlaouen, Claude Férec, Isabelle Callebaut and Gérald Le Gac.

8th CONGRESS OF THE INTERNATIONAL BIOIRON SOCIETY, EMBL Heidelberg, Germany. May 5-10 2019. Link

(7) « CFTR conformational landscape explored by computational approaches »

Ahmad Elbahnsi*, Fabio Pietrucci, Brice Hoffmann, Benjamen Boucherle, Renaud Zelli, Lionel Froux, Arnaud Billet, Nesrine Baatallah, Pierre Lehn, Isabelle Sermet-Gaudelus, Aleksander Edelman, Alexandre Hinzpeter, Frederic Becq, Jean-Luc Décout, Jean-Paul Mornon, Isabelle Callebaut.

16th Basic Science European Cystic Fibrosis Conference, Dubrovnik, Croatia. March 27-30 2018. Link