About me

Currently working at the University of Iceland, I am ultimately interested in understanding how the dynamics of gene regulation modulate cell states and their transitions. 

My research focuses on the quantitative prediction of cell responses to perturbations, including metabolic transitions at single-cell resolution, with applications to clinically relevant problems like recurrence in glioblastoma. More details about my research can be found here.

Previously, I worked at the University of Vic - Central University of Catalonia as professor in bioinformatics. Earlier at the University of Iceland I worked on the identification of novel transcriptional and metabolic mechanisms leading to endothelial dysfunction. Before that, at the Institute for Systems Biology in Seattle, USA, I studied multiple biological phenomena: (1) microbial cell state transitions, (2) transcriptome & metabolome interplay, (3) translational regulation in Archaea, (4) experimental evolution of adaptive traits, and (5) tumor recurrence and resistance. 

Earlier, as a postdoc in Andreas Wagner's lab at the University of Zurich, I worked on two research projects, studying (1) how mutations can be interpreted as mapping functions in parameter space from healthy to disease phenotype, and (2) how to use noise as a tool to select models that explain a time series experimental data set.

My education has been shaped by several institutions. I obtained my doctorate degree at Pompeu Fabra University  (October 2010) under the supervision of Jordi Villà i Freixa. Besides, I did multiple research stays at different institutions such as Caltech, CNIO, University College London, University of Pittsburgh and the University of Southern Denmark. In 2003, I graduated in Biochemistry (highest graduation GPA of the year) from Navarra University. 

If you would like to contact me, please feel free to drop me a line at adrianlopezgarciadelomana at gmail dot com 

    Last update: 01.06.2025