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2024 AI-Generated Proteins Achieve 84% Expression Success in the Lab
https://310.ai/blog/testing-96-novel-ai-proteins
2024 Text2Enzyme: MP4 AI generates proteins across full EC universe
https://medium.com/310-ai/text2enzyme-mp4-ai-generates-proteins-across-full-ec-universe-587fd212e6ea
2024 MP4: AI Text2Protein Breakthrough Tackles the Molecule Programming Challenge
https://medium.com/310-ai/mpm4-ai-text2protein-breakthrough-tackles-the-molecule-programming-challenge-870045a8c1ad
2025 Cell Rep Med: Lin H, Case Ry, Wei KY et al.
Characterization and comparative analysis of multifunctional natural killer cell engagers during antitumor responses
GenBio@NeurIPS2023: Chu SKS & Wei KY
Conditional generation of paired antibody chain sequences through encoder-decoder language model
https://arxiv.org/abs/2301.02748
2023 mAbs: Harmalkar A, Rao R, Honer J, Deisting W, Anlahr J, Hoenig A, Czwikla J, Sienz-Widmann E, Rau D, Rice A, Riley TP, Li D, Catterall HB, Tinberg CE, Gray JJ & Wei KY
Towards generalizable prediction of antibody thermostability using machine learning on sequence and structure features
https://www.tandfonline.com/doi/full/10.1080/19420862.2022.2163584
2021 BBA - Molecular Cell Research: Hasegawa H, Wei KY, Thomas M, Li P, Kinderman F, Franey H, Liu L, & Jocabsen F
Light chain subunit of a poorly soluble human IgG2gamma crystallizes in physiological pH environment both in cellulo and in vitro
https://www.sciencedirect.com/science/article/pii/S0167488921001324
2020 PNAS: Wei KY et al.
Computational design of closely related proteins that adopt two well-defined but structurally divergent folds.
2019 eLIFE: Park J, Selvaraj B, McShan AC, Boyken SE, Wei KY, et al.
De novo design of a homo-trimeric amantadine-binding protein.
2019 MBoC: Harris AR, Belardi B, Jreij J, Wei K, et al.
Steric regulation of tandem calponin homology domain actin-binding affinity.
2019 Science: Boyken SE, Benhaim MA, Busch F, Jia M, Bick MJ, Choi J, Chen Z, Walkey C, Mileant A, Sahasrabuddhe A, Klima JC, Wei KY, et al.
De novo design of tunable, pH-driven conformational changes.
2018 Science: Lu P, Min D, DiMaio F, Wei KY, et al.
Accurate computational design of multipass transmembrane proteins.
2015 J of Biol Eng: Wei KY & Smolke CD
Engineering synthetic ligand-responsive RNA devices for controlling the cell cycle.
2013 Annu Rev Chem Biomol Eng: Wei KY*, Wang Y-H*, Smolke CD.
Synthetic biology: advancing the design of diverse genetic systems.
2013 Biotechnol Bioeng: Wei KY, Chen YY, Smolke CD.
A yeast-based rapid prototype platform for gene-control elements in mammalian cells.
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