Publications

PUBLICATIONS

The following publications summarise the progress of our developments on the improved material for treating stress urinary incontinence.

Ongoing, as yet unreported, activity relates to manufacturing upscaling and the design of more consistent approaches to the insertion and adjustment of the device within the patient.

Hillary CJ, Roman S, Bullock AJ, Green, NH, Chapple CR, MacNeil S (2016) Developing Repair Materials for Stress Urinary Incontinence to Withstand Dynamic Distension. PLoS ONE 11(3): e0149971. DOI:10.1371/journal.pone.0149971.
Roman S et al (2016) Evaluating Alternative Materials for the Treatment of Stress Urinary Incontinence and Pelvic Organ Prolapse: A Comparison of the In Vivo Response to Meshes Implanted in Rabbits. The Journal of Urology 196, 261-269. DOI: 10.1016/j.juro.2016.02.067.
Roman S et al (2016) Biodegradable scaffolds designed to mimic fascia-like properties for the treatment of pelvic organ prolapse and stress urinary incontinence. Journal of Biomaterials Applications 30(10) 1578–1588. DOI: 10.1177/0885328216633373 jba.sagepub.com.
Hympánová L et al (2020) Assessment of Electrospun and Ultra-lightweight Polypropylene Meshes in the Sheep Model for Vaginal Surgery. European Urology Focus 6, 190-198. DOI: 10.1016/j.euf.2018.07.024.
Farr NTH et al (2021) A novel characterisation approach to reveal the mechano–chemical effects of oxidation and dynamic distension on polypropylene surgical mesh. RSC Advances, 11(55) 34710-34723. DOI: 10.1039/d1ra05944k.
Farr NTH. et al (2024) Uncovering the relationship between macrophages and polypropylene surgical mesh, Biomaterials Advances, 159 (2024). DOI: 10.1016/j.bioadv.2024.213800.
Chapple, CR. Bullock, AJ & MacNeil, S, Where are we in 2024 in the development of materials for surgical treatment of pelvic organ prolapse and stress urinary incontinence? Current Opinion in Urology. DOI: 10.1097/MOU.0000000000001217.
European Patent EP 3 634 509 B1 “Scaffold”.

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