Seminar Organising Committee

Alexandra Moreno Mitchell

I am a PhD student in the Faculty of Health and am working on an interdisciplinary project between the Department of Chemistry and the Division of Clinical Medicine with Dr Tim Craggs and Dr Chris Toseland. My project aims to develop and optimise an assay for early cancer detection using single molecule technology.

Evelyn Smith

In October 2018 I began studying for a PhD supervised by Dr. Alison Twelvetrees and Dr Tim Craggs, applying single molecule FRET to understand kinesin activation. I successfully completed my PhD in January 2023 and now work as a postdoc.

Georgia Taylor-Vine

I am a student within the Department of Chemistry, working on an interdisciplinary project across the Department of Chemistry and the Division of Clinical Medicine with Dr Tim Craggs, Dr Gareth Richards and Prof Joe Harrity. The aim of my project is to create a new SMALP based drug screening assay for GPCR heterodimers, ultimately focusing on the use of single molecule fluorescence correlation spectroscopy which will be conducted within the Craggs lab.

Katie Gelder

I am a postdoctoral researcher in Dr Tatyana Shelkovnikova’s lab within Sheffield Institute of Translational Neuroscience (SITraN). My background is in phase separated condensates and how this is regulated and affects protein activity. My interests include single molecule imaging, single molecule fluorescence resonance energy transfer (smFRET) and cryo-correlative light and election microscopy (cryo-CLEM). Anything that involves blobs and microscopy, count me in!

Brychan Evans

I am a bioscience PhD student in the Bose Lab, supervised by Dr Dan Bose in collaboration with Dr Ali Twelvetrees (SITraN) and Dr Tim Craggs (Department of Chemistry). My project focuses on how sequence differences within the intrinsically disordered regions (IDRs) of the paralogous transcriptional coactivators CBP and p300 may contribute to divergence in their function. This will involve lots of microscopy including single particle tracking!

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