Under preparation

L. Pasquina Lemonche, J. K. Hobbs, S. J. Foster.; Book chapter: Atomic force microscopy for the study of bacterial cell wall architecture: purified peptidoglycan and live cells. Methods in Molecular Biology (submitted 2022)

R. Garcia-Maset, S. C. L. Hall, L. A. Clifton, A. Hapeshi, L. Pasquina-Lemonche, J. K. Hobbs, F. Harrison, S. Perrier.; Assessing the action of synthetic nanoengineered antimicrobial polymers (SNAPs) against the bacterial membrane of Pseudomonas aeruginosa. (submitted 2023 - waiting on review)

L. Pasquina-Lemonche*, O. Meacock*, A. Feyisara-Olulana, W. M. Durham, S. J. Foster, E. Garner and J. K Hobbs.; Automated Image segmentation and analysis to study fibres in AFM images. (To be submitted 2024) - *(Authors contributed equally)

L. Pasquina-Lemonche*, S. Nuñez-Pertiñez*, A. Adedeji, J. Wilson, A. Alomari, X. Chen, N. Mullin, J. K. Hobbs.; FIJI routine PoreAFM: an automatic tool to quantitatively analyse porous materials from topography AFM images and produce 3D tomography representations. (To be submitted 2024) - *(Authors contributed equally)

Published

2024

Two codependent routes lead to high-level MRSA

Adedeji-Olulana, A.F., Wacnik, K., Lafage, L., Pasquina-Lemonche, L., Tinajero-Trejo, M., Sutton, J.A., Bilyk, B., Irving, S.E., Portman Ross, C.J., Meacock, O.J.,  Randerson, S.A., Beattie, E., Owen, D.S., Florence, J., Durham, W. M., Hornby, D. P., Corrigan, R. M., Green, J., Hobbs, J. K. and Foster, S. J., Science, 386(6721), pp.573-580.  (2024)

Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis

V. Salgueiro, J. Bertol, C. Gutierrez, A. Palacios, L. Pasquina-Lemonche, A. Espalliat, L. Lerna, B. Weinrick, J. L. Lavin, F. Elortza, M. Azkalgorta, A. Prieto, P. Buendía-Nacarino, J. L. Luque-García, O. Neyrolles, F. Cava, J. K. Hobbs, J. Sanz, R. Prados-Rosales, eLife. 13, RP94982 (2024)

2023

Mechanism of Action of Oxazoline-Based Antimicrobial Polymers Against Staphylococcus aureus: In Vivo Antimicrobial Activity Evaluation

M. Concilio, R. Garcia-Maset, L. Pasquina-Lemonche, V. Kontrimas, J. Song, S. Rajendrakumar, F. Harrison, C. Remzi-Becer, S. Perrier, Adv. Healthcare Mater.12, 2301961 (2023)

2022

The Staphylococcus aureus cell division protein, DivIC, interacts with the cell wall and controls its biosynthesis.

M. Tinajero-Trejo,* O. Carnell*, A. F. Kabli, L. Pasquina-Lemonche, L. Lafage, A. Han, J. Hobbs, S. Foster.; Commun Biol 5, 1228 (2022) - (*Authors Equally Contributed)

2021

Demonstration of the role of cell wall homeostasis in Staphylococcus aureus growth and the action of bactericidal antibiotics.

B. Salamaga*, L. Kong*, L. Pasquina-Lemonche*, L. Lafage*, M. Muhlen*, J. Gibson, D. Grybchuk, A. Tooke, V. Panchal, E. Culp, E. Tatham, M. O’Kane, T. Catley, S. Renshaw, G. Wright, P. Plevka, P. Bullough, A. Han, J. Hobbs, S. Foster; PNAS, 118(44), e2106022118 (2021) -  (*Authors Equally Contributed)

Correlative Super-Resolution Optical and Atomic Force Microscopy Reveals Relationships Between Bacterial Cell Wall Architecture and Synthesis in Bacillus subtilis. 

R. Tank,* V. Lund,* S. Kumar, R. Turner, L. Lafage, L. Pasquina-Lemonche, P. Bullough, A. Cadby, S. Foster, J. Hobbs.;  ACS nano 15 (10), (2021) -  (*Authors Equally Contributed)

2020

The architecture of the Gram-positive bacterial cell wall. View this article in WRRO 

Pasquina-Lemonche L*, Burns J*, Turner RD, Kumar S, Tank R, Mullin N, Wilson JS, Chakrabarti B, Bullough PA, Foster SJ and Hobbs JK, Nature, 582, 294–297 (2020) (*Authors Equally Contributed)

Rational Design and Self-Assembly of Coiled-Coil Linked SasG Protein Fibrils.

L. Jasaitis, D. Silver, E. Rawlings, T. Peters, F. Whelan, L. Regan, L. Pasquina-Lemonche, J. Potts, S. Johnson, S. Staniland.; ACS Synthetic Biology 9 (7),1599-1607 (2020).

2018

Insights into the structure and nanomechanics of a quatsome membrane by force spectroscopy measurements and molecular simulations. View this article in WRRO

Gumí-Audenis, B., Illa-Tuset, S., Grimaldi, N., Pasquina-Lemonche, L., Ferrer-Tasies, L., Sanz, F., Veciana, J., Ratera, I., Faraudo, J., Ventosa, N., Giannotti, M. I.;  Nanoscale 10 (48), 23001-23011. (2018)