Trial Summary

Trial Summary

The aim of the ORION trial is to assess whether radiofrequency ablation (RFA) is as efficacious as existing methods of treating haemorrhoids and if it is superior in terms of pain.

ORION is a multicentre randomised controlled trial that compares RFA’s effectiveness with the surgeon’s choice of surgery, for patients whose haemorrhoids are severe enough to warrant surgical intervention. The control arm of the trial is the surgeon’s choice of any of the three NICE recommended surgical procedures – haemorrhoidal artery ligation, stapled haemorrhoidopexy or haemorrhoidectomy – and the intervention arm is Radiofrequency ablation. Patients will be randomly assigned to either arm in a ratio or 1:1. 

Where can I find out more information?