Wilding, C. Y. P.; Bourne, R. A.; Warren, N. J. Integrating mechanistic modelling with Bayesian optimisation: accelerated self-driving laboratories for RAFT polymerisation. Digital Discovery 2025, 4 (10), 2797-2803, https://10.1039/D5DD00258C
Garg, S.; Singla, P.; Kaur, S.; Canfarotta, F.; Velliou, E.; Dawson, J. A.; Kapur, N.; Warren, N. J.; Amarnath, S.; Peeters, M. Future Perspectives on the Automation and Biocompatibility of Molecularly Imprinted Polymers for Healthcare Applications. Macromolecules 2025, 58 (3), 1157-1168. DOI: https://10.1021/acs.macromol.4c01621
Grimm, A.P., Knox, S.T., Wilding, C.Y.P., Jones, H.A., Schmidt, B., Piskljonow, O., Voll, D., Schmitt, C.W., Warren, N.J., Théato, P., Versatile Flow Reactor Platform for Machine Learning Guided RAFT Synthesis, Amidation of Poly(Pentafluorophenyl Acrylate). Macromolecular Rapid Communications 2025 https://doi.org/10.1002/marc.202500264
Knox, S. T.; Wu, K. E.; Islam, N.; O'Connell, R.; Pittaway, P. M.; Chingono, K. E.; Oyekan, J.; Panoutsos, G.; Chamberlain, T. W.; Bourne, R. A.; et al. Self-driving laboratory platform for many-objective self-optimisation of polymer nanoparticle synthesis with cloud-integrated machine learning and orthogonal online analytics. Polymer Chemistry 2025, 16 (12), 1355-1364, https://10.1039/D5PY00123D
Pittaway, P, M; Chingono, K. E.; Knox, S. T.; Martin, E.; Bourne, R. A.; Cayre, O. J.; Kapur, N.; Booth, J.; Capomaccio, R.;
Pedge, N,; Warren, N. J. Exploiting Online Spatially Resolved Dynamic Light Scattering and Flow-NMR for Automated
Size Targeting of PISA-Synthesized Block Copolymer Nanoparticles ACS Polymer Au 2025, 5, 1
Pittaway, P, M; Knox, S. T.; Cayre, O. J.; Kapur, N.; Golden, L.; Drillieres. S.; Warren, N. J. Self-driving laboratory for emulsion polymerization Chemical Engineering Journal 2025, 160700
Hilton, E. M.; Jhons, Y.; Warren, N. J.; Wilson, A. J.; Polymers with quadruple hydrogen-bonding end groups: controlling molecular weight using a small molecule photoswitch Polymer Chemistry 2024, 15, 4115
Dixon, T. M.; Williams, J.; Besenhard, M.; Howard, R. M; MacGregor, J.; Peach, P.; Clayton, A. D.; Warren, N. J.; Bourne, R. A.; Operator-free HPLC automated method development guided by Bayesian optimization Digital Discovery 2024, 8, 1591
Hilton, E. M.; Jinks; M. A.; Burnett, A. D.; Warren, N. J.; Wilson, A. J.; Visible-light driven control over oligomerization of triple and quadruply hydrogen-bonded ditopic self-assemblies Chem Eur J. 2024, e202304033
Pugsley, C.; Isaac, E.; Warren, N.; Stacey, M.; Cappelle, K.; Dominguez-Espinosa, R.; Cayre, O., Effective delivery and selective insecticidal activity of double-stranded RNA via complexation with diblock copolymer varies with polymer block composition. Pest Management Science 2024 80, 669
Morrell, A.; Warren, N.J.; Thornton, P.,The Production of Polysarcosine‐Containing Nanoparticles by Ring‐Opening Polymerization‐Induced Self‐Assembly. Macromolecular Rapid Communications 2024, 2400103
Lockwood, A. P. G.; Wadsley, G.; Warren, N. J.; Peakall, J.; Webber, G. B. Wanless, E. J.; Rhodes, D,; Barnes, M.; Harbottle, D.; Hunter, T. N.; Amphiphilic block copolymers as dual flocculation-flotation agents for rapid solid-liquid separation of radioactive wastes Separation and Purification Technology 2023, 124387
Guild, J. D.; Knox, S. T.; Burholt, S. B.; Hilton, E. M.; Terrill, N. J.; Schroeder, S. L. M.; Warren, N. J. Continuous-Flow Laboratory SAXS for In Situ Determination of the Impact of Hydrophilic Block Length on Spherical Nano-Object Formation during Polymerization-Induced Self-Assembly. Macromolecules 2023, 56, 6426
Wilding, C. Y. P.; Knox, S. T.; Bourne, R. A.; Warren, N. J., Development and Experimental Validation of a Dispersity Model for In Silico RAFT Polymerization. Macromolecules 2023, 56 , 1581.
Pittaway, P. M.; Ghasemi, G.; Knox, S. T.; Cayre, O. J.; Kapur, N.; Warren, N. J. Continuous synthesis of block copolymer nanoparticles via telescoped RAFT solution and dispersion polymerisation in a miniature CSTR cascade. Reaction Chemistry & Engineering 2023, 8 , 707
Dent, F. J.; Harbottle, D.; Warren, N. J.; Khodaparast, S., Exploiting breath figure reversibility for in situ pattern modulation and hierarchical design. Soft Matter 2023, 19, 2737.
Kershaw, O. J.; Clayton, A. D.; Manson, J. A.; Barthelme, A.; Pavey, J.; Peach, P.; Mustakis, J.; Howard, R. M.; Chamberlain, T. W.; Warren, N. J.; Bourne, R. A., Machine learning directed multi-objective optimization of mixed variable chemical systems. Chemical Engineering Journal 2023, 451, 138443.
Pugsley, C. E.; Isaac, R. E.; Warren, N. J.; Cayre, O. J., Linear ABC amphiphilic triblock copolymers for complexation and protection of dsRNA. Polymer Chemistry 2022, 13, 5707.
Pugsley, C. E.; Isaac, R. E.; Warren, N. J.; Behra, J. S.; Cappelle, K.; Dominguez-Espinosa, R.; Cayre, O. J., Protection of Double-Stranded RNA via Complexation with Double Hydrophilic Block Copolymers: Influence of Neutral Block Length in Biologically Relevant Environments. Biomacromolecules 2022, 23, 2362.
Czubak, B.; Warren, N. J.; Nagaraj, M., Steroid-Based Liquid Crystalline Polymers: Responsive and Biocompatible Materials of the Future. Crystals 2022, 12, 1000.
Dent, F. J.; Harbottle, D.; Warren, N. J.; Khodaparast, S., Temporally Arrested Breath Figure. ACS Applied Materials & Interfaces 2022, 14, 27435.
Knox, S. T.; Parkinson, S. J.; Wilding, C. Y. P.; Bourne, R. A.; Warren, N. J.,* Autonomous polymer synthesis delivered by multi-objective closed-loop optimisation. Polymer Chemistry 2022, 13, 1576-1585.
Brotherton E. E; Jesson C.P.; , Warren N.J.; Smallridge M. J., Armes S. P., New Aldehyde‐Functional Methacrylic Water‐Soluble Polymers Angewandte Chemie International Edition. 2021, 133,12139-12144
Pugsley, C. E.; Isaac, R. E.; Warren, N. J.; Cayre, O. J., Recent Advances in Engineered Nanoparticles for RNAi-Mediated Crop Protection Against Insect Pests. 2021, 3
Lockwood, A. P. G.; Peakall, J.; Warren, N. J.; Randall, G.; Barnes, M.; Harbottle, D.; Hunter, T. N., Structure and sedimentation characterisation of sheared Mg(OH)2 suspensions flocculated with anionic polymers. Chemical Engineering Science 2021, 231, 116274.
Kaskiewicz, P. L.; Rosbottom, I.; Hammond, R. B.; Warren, N. J.; Morton, C.; Dowding, P. J.; George, N.; Roberts, K. J., Understanding and Designing Tailor-Made Additives for Controlling Nucleation: Case Study of p-Aminobenzoic Acid Crystallizing from Ethanolic Solutions. Crystal Growth & Design 2021, 21, 1946-1958.
Nahi O., Cayre O. J.; Kim, Y-Y., Smith, A. J., Warren, N. J., Meldrum, F. C., A Facile Method for Generating Worm-like Micelles with Controlled Lengths and Narrow Polydispersity Chem. Commun., 2020, 56, 7463
Parkinson, S..; Knox, S. T.; Bourne, R. A.; Warren, N. J*.; Rapid Production of Block Copolymer Nano-Objects via Continuous-Flow Ultrafast RAFT Dispersion Polymerisation, Polymer Chemistry 2020 11, 3465-3474
Spelat, R.; Ferro, F.; Contessotto, P.; Warren, N. J.; Marsico, G.; Armes, S. P.; Pandit, A., A worm gel-based 3D model to elucidate the paracrine interaction between multiple myeloma and mesenchymal stem cells. Materials Today Bio 2020, 5, 100040
Knox, S. Warren, N. J.* Enabling technologies in polymer synthesis: accessing a new design space for advanced polymer materials Reaction Chemistry & Engineering., 2020, 5, 405-423
Knox, S. ; Stone, R.; Parkinson, S.; and Warren, N. J.* Online Monitoring of Radical Polymerisation using low-field Flow-NMR; Polymer Chemistry, 2019, 10, 4774-4778
Kaskiewicz, P. L.; Xua, G.; Lai, X.; Warren, N. J, Roberts, K J., Morton, C.; Dowding, P.; George, N.; An accelerated approach to the prediction of the crystallisability of slowly nucleating systems Organic Process Research and Development, 2019 23 (9), 1948
Yua, H.; Ingram, N.; Rowley, J. V.; Parkinson, S.; Green, D. C.; Warren, N. J and Thornton, P. D., Thermoresponsive Polysarcosine-Based Nanoparticles Journal of Materials Chemistry B, 2019, 7, 4217-4223
Parkinson, S.; Hondow N. S.; Conteh, J.S.; Bourne, R. A,; Warren, N. J.* All-aqueous continuous-flow RAFT dispersion polymerisation for efficient preparation of diblock copolymer spheres, worms and vesicles. Reaction Chemistry & Engineering 2019. 4, 852-861
Warren, N. J.*; Derry, M. J.; Mykhaylyk, O. O.; Lovett, J. R.; Ratcliffe, L. P. D.; Ladmiral, V.; Blanazs, A.; Fielding, L. A.; Armes, S. P. Critical Dependence of Molecular Weight on Thermoresponsive Behavior of Diblock Copolymer Worm Gels in Aqueous Solution. Macromolecules 2018, 51 (21), 8357-8371
Madsen, J.; Madden, G.; Themistou, E.; Warren, N. J.; Armes, S. P. pH-Responsive diblock copolymers with two different fluorescent labels for simultaneous monitoring of micellar self-assembly and degree of protonation. Polymer Chemistry 2018, 9 (21), 2964-2976
Lovett, J. R.; Derry, M. J.; Yang, P.; Hatton, F. L.; Warren, N. J.; Fowler, Patrick W.; Armes, S. P. Can percolation theory explain the gelation behavior of diblock copolymer worms? Chemical Science 2018, 9 (35), 7138-7144
Doherty, S.; Knight, J. G.; Backhouse, T.; Abood, E.; Al-shaikh, H.; Clemmet, A. R.; Ellison, J. R.; Bourne, R. A.; Chamberlain, T. W.; Stones, R.; Warren, N. J.; Fairlamb, I. J. S.; Lovelock, K. R. J. Heteroatom Donor-Decorated Polymer-Immobilized Ionic Liquid Stabilized Palladium Nanoparticles: Efficient Catalysts for Room-Temperature Suzuki-Miyaura Cross-Coupling in Aqueous Media. Advanced Synthesis & Catalysis 2018, 360, 1–17
Steinschulte, A. A.; Scotti, A.; Rahimi, K.; Nevskyi, O.; Oppermann, A.; Schneider, S.; Bochenek, S.; Schulte, M. F.; Geisel, K.; Jansen, F.; Jung, A.; Mallmann, S.; Winter, R.; Richtering, W.; Wöll, D.; Schweins, R.; Warren, N. J.*; Plamper, F. A., Stimulated Transitions of Directed Nonequilibrium Self-Assemblies. Advanced Materials, 2017, 1703495 (Joint final and corresponding author)
Ratcliffe, L. P. D.; Bentley, K. J.; Wehr, R.; Warren, N. J.*; Saunders, B. R. Armes, S. P.; Cationic disulfide-functionalized worm gels Polymer Chemistry, 2017,8, 5962-5971
Jesson C. P.; Pearce C. M.; Simon H.; Werner A.; Cunningham V. J.; Lovett J. R.; Smallridge M. J.; Warren N. J.*, and Armes S. P.; H2O2 Enables Convenient Removal of RAFT End-Groups from Block Copolymer Nano-Objects Prepared via Polymerization-Induced Self-Assembly in Water. Macromolecules, 2017, 50 (1), 182–191
Zhang, Z. J.; Madsen, J.; Warren, N. J.; Mears, M.; Leggett, G. J.; Lewis, A. L.; Geoghegan, M,; Influence of Salt on the Solution Dynamics of a Phosphorylcholine-Based Polyzwitterion. European Polymer Journal, 2017, 87, 449–457
Rymaruk M. J.; Thompson K. L.; Derry M. J.; Warren N. J.; Ratcliffe L. P. D.; Williams C. N.; Brown S. L.; Armes S. P. Bespoke contrast-matched diblock copolymer nanoparticles enable the rational design of highly transparent Pickering double emulsions. Nanoscale 2016, 8, (30), 14497-14506
Mykhaylyk, O. O.; Warren, N. J.; Parnell, A. J.; Pfeifer, G.; Laeuger, J. Applications of shear-induced polarized light imaging (SIPLI) technique for mechano-optical rheology of polymers and soft matter materials. Journal of Polymer Science Part B: Polymer Physics 2016, 54 (21), 2151-2170.
Derry, M. J.; Fielding, L. A.; Warren, N. J.; Mable, C. J.; Smith, A. J.; Mykhaylyk, O. O.; Armes, S. P. In situ small-angle X-ray scattering studies of sterically-stabilized diblock copolymer nanoparticles formed during polymerization-induced self-assembly in non-polar media. Chemical Science 2016, 7 (8), 5078-5090.
Williams, M.; Penfold, N. J. W.; Lovett, J. R.; Warren, N. J.; Douglas, C. W. I.; Doroshenko, N.; Verstraete, P.; Smets, J.; Armes, S. P. Bespoke cationic nano-objects via RAFT aqueous dispersion polymerisation. Polymer Chemistry 2016, 7 (23), 3864-3873.
Penfold, N. J. W.; Lovett, J. R.; Warren, N. J.; Verstraete, P.; Smets, J.; Armes, S. P. pH-Responsive non-ionic diblock copolymers: protonation of a morpholine end-group induces an order-order transition. Polymer Chemistry 2016, 7 (1), 79-88.
Lovett, J. R.; Warren, N. J.; Armes, S. P. Order-Order Morphological Transitions for Dual Stimulus Responsive Diblock Copolymer Vesicles. Macromolecules 2016, 49 (3), 1016-1025.
Lovett, J. R.; Ratcliffe, L. P. D.; Warren, N. J.; Armes, S. P.; Smallridge, M. J.; Cracknell, R. B.; Saunders, B. R. A Robust Cross-Linking Strategy for Block Copolymer Worms Prepared via Polymerization-Induced Self-Assembly. Macromolecules 2016, 49 (8), 2928-2941.
Canton, I.; Warren, N. J.; Chahal, A.; Amps, K.; Wood, A.; Weightman, R.; Wang, E.; Moore, H.; Armes, S. P. Mucin-Inspired Thermoresponsive Synthetic Hydrogels Induce Stasis in Human Pluripotent Stem Cells and Human Embryos. ACS Central Science 2016, 2 (2), 65-74.
Warren, N. J.; Mykhaylyk, O. O.; Ryan, A. J.; Williams, M.; Doussineau, T.; Dugourd, P.; Antoine, R.; Portale, G.; Armes, S. P. Testing the vesicular morphology to destruction: birth and death of diblock copolymer vesicles prepared via polymerization-induced self-assembly. Journal of the American Chemical Society 2015, 137 (5), 1929-37.
Simon, K. A.; Warren, N. J.; Mosadegh, B.; Mohammady, M. R.; Whitesides, G. M.; Armes, S. P. Disulfide-Based Diblock Copolymer Worm Gels: A Wholly-Synthetic Thermoreversible 3D Matrix for Sheet-Based Cultures. Biomacromolecules 2015, 16 (12), 3952–3958
Mable, C. J.; Warren, N. J.; Thompson, K. L.; Mykhaylyk, O. O.; Armes, S. P. Framboidal ABC triblock copolymer vesicles: a new class of efficient Pickering emulsifier. Chemical Science 2015, 6 (11), 6179-6188.
Lovett, J. R.; Warren, N. J.; Ratcliffe, L. P. D.; Kocik, M. K.; Armes, S. P. pH-Responsive Non-Ionic Diblock Copolymers: Ionization of Carboxylic Acid End-Groups Induces an Order–Order Morphological Transition. Angewandte Chemie International Edition 2015, 54 (4), 1279-1283.
Lopez-Oliva, A. P.; Warren, N. J.*; Rajkumar, A.; Mykhaylyk, O. O.; Derry, M. J.; Doncom, K. E. B.; Rymaruk, M. J.; Armes, S. P. Polydimethylsiloxane-Based Diblock Copolymer Nano-objects Prepared in Nonpolar Media via RAFT-Mediated Polymerization-Induced Self-Assembly. Macromolecules 2015, 48 (11), 3547-3555.
Doncom, K. E. B.; Warren, N. J.; Armes, S. P. Polysulfobetaine-based diblock copolymer nano-objects via polymerization-induced self-assembly. Polymer Chemistry 2015, 6 (41), 7264-7273
Williams, M.; Warren, N. J.; Fielding, L. A.; Armes, S. P.; Verstraete, P.; Smets, J. Preparation of Double Emulsions using Hybrid Polymer/Silica Particles: New Pickering Emulsifiers with Adjustable Surface Wettability. ACS Applied Materials & Interfaces 2014, 6 (23), 20919-20927.
Warren, N. J.; Armes, S. P. Polymerization-Induced Self-Assembly of Block Copolymer Nano-objects via RAFT Aqueous Dispersion Polymerization. Journal of the American Chemical Society 2014, 136 (29), 10174-10185.
Thompson, K. L.; Mable, C. J.; Cockram, A.; Warren, N. J.; Cunningham, V. J.; Jones, E. R.; Verber, R.; Armes, S. P. Are block copolymer worms more effective Pickering emulsifiers than block copolymer spheres? Soft Matter 2014, 10 (43), 8615-8626.
Pegoraro, C.; Cecchin, D.; Madsen, J.; Warren, N. J.; Armes, S. P.; MacNeil, S.; Lewis, A.; Battaglia, G. Translocation of flexible polymersomes across pores at the nanoscale. Biomaterials Science 2014, 2 (5), 680-692.
Cunningham, V. J.; Ratcliffe, L. P. D.; Blanazs, A.; Warren, N. J.; Smith, A. J.; Mykhaylyk, O. O.; Armes, S. P. Tuning the critical gelation temperature of thermo-responsive diblock copolymer worm gels. Polymer Chemistry 2014, 5 (21), 6307-6317.
Colley, H. E.; Hearnden, V.; Avila-Olias, M.; Cecchin, D.; Canton, I.; Madsen, J.; MacNeil, S.; Warren, N. J.; Hu, K.; McKeating, J. A.; Armes, S. P.; Murdoch, C.; Thornhill, M. H.; Battaglia, G. Polymersome-Mediated Delivery of Combination Anticancer Therapy to Head and Neck Cancer Cells: 2D and 3D in Vitro Evaluation. Molecular Pharmaceutics 2014, 11 (4), 1176-1188.
Wayakanon, K.; Thornhill, M. H.; Douglas, C. W. I.; Lewis, A. L.; Warren, N. J.; Pinnock, A.; Armes, S. P.; Battaglia, G.; Murdoch, C. Polymersome-mediated intracellular delivery of antibiotics to treat Porphyromonas gingivalis-infected oral epithelial cells. The FASEB Journal 2013, 27 (11), 4455-4465.
Warren, N. J.*; Mykhaylyk, O. O.; Mahmood, D.; Ryan, A. J.; Armes, S. P. RAFT Aqueous Dispersion Polymerization Yields Poly(ethylene glycol)-Based Diblock Copolymer Nano-Objects with Predictable Single Phase Morphologies. Journal of the American Chemical Society 2013, 136 (3), 1023-1033.
Pegoraro, C.; Cecchin, D.; Gracia, L. S.; Warren, N. J.; Madsen, J.; Armes, S. P.; Lewis, A.; MacNeil, S.; Battaglia, G. Enhanced drug delivery to melanoma cells using PMPC-PDPA polymersomes. Cancer Letters 2013, 334 (2), 328-337.
Pearson, R. T.; Warren, N. J.; Lewis, A. L.; Armes, S. P.; Battaglia, G. Effect of pH and Temperature on PMPC–PDPA Copolymer Self-Assembly. Macromolecules 2013, 46 (4), 1400-1407.
Madsen, J.; Canton, I.; Warren, N. J.; Themistou, E.; Blanazs, A.; Ustbas, B.; Tian, X.; Pearson, R.; Battaglia, G.; Lewis, A. L.; Armes, S. P. Nile Blue-Based Nanosized pH Sensors for Simultaneous Far-Red and Near-Infrared Live Bioimaging. Journal of the American Chemical Society 2013, 135 (39), 14863-14870.
Canton, I.; Massignani, M.; Patikarnmonthon, N.; Chierico, L.; Robertson, J.; Renshaw, S. A.; Warren, N. J.; Madsen, J. P.; Armes, S. P.; Lewis, A. L.; Battaglia, G. Fully synthetic polymer vesicles for intracellular delivery of antibodies in live cells. The FASEB Journal 2013, 27 (1), 98-108.
Warren, N. J.; Muise, C.; Stephens, A.; Armes, S. P.; Lewis, A. L. Near-Monodisperse Poly(2-(methacryloyloxy)ethyl phosphorylcholine)-Based Macromonomers Prepared by Atom Transfer Radical Polymerization and Thiol–Ene Click Chemistry: Novel Reactive Steric Stabilizers for Aqueous Emulsion Polymerization. Langmuir 2011, 28 (5), 2928-2936.
Madsen, J.; Warren, N. J.; Armes, S. P.; Lewis, A. L. Synthesis of Rhodamine 6G-Based Compounds for the ATRP Synthesis of Fluorescently Labeled Biocompatible Polymers. Biomacromolecules 2011, 12 (6), 2225-2234.
LoPresti, C.; Massignani, M.; Fernyhough, C.; Blanazs, A.; Ryan, A. J.; Madsen, J.; Warren, N. J.; Armes, S. P.; Lewis, A. L.; Chirasatitsin, S.; Engler, A. J.; Battaglia, G. Controlling Polymersome Surface Topology at the Nanoscale by Membrane Confined Polymer/Polymer Phase Separation. ACS Nano 2011, 5 (3), 1775-1784.
Blanazs, A.; Warren, N. J.; Lewis, A. L.; Armes, S. P.; Ryan, A. J. Self-assembly of double hydrophilic block copolymers in concentrated aqueous solution. Soft Matter 2011, 7 (14), 6399-6403.
Battaglia, G.; LoPresti, C.; Massignani, M.; Warren, N. J.; Madsen, J.; Forster, S.; Vasilev, C.; Hobbs, J. K.; Armes, S. P.; Chirasatitsin, S.; Engler, A. J. Wet Nanoscale Imaging and Testing of Polymersomes. Small 2011, 7 (14), 2010-2015.
Lomas, H.; Du, J.; Canton, I.; Madsen, J.; Warren, N. J.; Armes, S. P.; Lewis, A. L.; Battaglia, G. Efficient Encapsulation of Plasmid DNA in pH-Sensitive PMPC–PDPA Polymersomes: Study of the Effect of PDPA Block Length on Copolymer–DNA Binding Affinity. Macromolecular Bioscience 2010, 10 (5), 513-530.
Bradley, M.; Vincent, B.; Warren, N. J.; Eastoe, J.; Vesperinas, A. Photoresponsive Surfactants in Microgel Dispersions. Langmuir 2005, 22 (1), 101-105.