The EVOLUTOR

EVOLUTOR is a smart device that automates adaptive laboratory evolution (ALE), one of the most powerful technologies for strain engineering. EVOLUTOR is unique in the market. Through automation, it reduces time and cost, removes human error, and enables better control over strain engineering. Importantly, it retains the simplicity and the versatility of ALE. It is a device designed for the field of biotechnology to engineer microbial strains for bioenergy, biochemicals, biomaterials, and biopharmaceutical production.

We couple EVOLUTOR technology and Multi-Genius technology to deliver state-of-the-art strain engineering.

EVOLUTOR hardware

• Miniaturized microbial bioreactor designed for cultivation of different microbial strains.

• Monitors and outputs real time cell density and temperature data.

• Detection capabilities include absorbance and fluorescence.

• Optional functionalities include pH and oxygen sensing.

EVOLUTOR software

• No fuss software for experimental setup that requires no programming or coding.

• Automates adaptive evolution workflow for strain engineering purposes.

• Enables different cultivation modes: serial, fed-batch, turbidostat and chemostat.

• Built-in mathematical models to describe the microbial growth behaviour.

• Remote access possible.

• Graphical display allows for direct visualisation of cultivation data.

Multi-Genius

• A proprietary strain engineering tool to create a large pool of microbial strain variants.

• Seamless coupling to EVOLUTOR for microbial enrichment.

• Quick and easy to identify beneficial mutations and the gene(s) responsible for the improved phenotype.