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Dr Annica K B Gad, Oncology & Metabolism
Dr Annica K B Gad, Oncology & Metabolism
Dr Gad´s research is focussed on understanding how regulators of the cytoskeleton control the contractile forces and stiffness of cells, through the use of biochemistry and advanced microscopy methods, such as super-resolution fluorescence microscopy, colloidal probe atomic force microscopy, and traction force microscopy, with the aim to identify novel target molecules for diagnosis and treatment for cancers.
email: a.k.gad@sheffield.ac.uk
Dr Elena Rainero, Biosciences
Dr Elena Rainero, Biosciences
The Rainero lab, in the School of Biosciences, is interested in understanding the contribution of extracellular matrix internalisation in controlling breast cancer cell growth and invasion.
email: e.rainero@sheffield.ac.uk
Dr Chris Toseland, Oncology & Metabolism
Dr Chris Toseland, Oncology & Metabolism
We explore how interactions between the cell and extracellular matrix impact functions within the nucleus such as genome organisation, sustainability to DNA damage and gene expression. We take a multi-disciplinary approach combining single molecule super resolution imaging, genomics and mechanobiology.
email: c.toseland@sheffield.ac.uk
Dr Emily Noël, Biosciences
Dr Emily Noël, Biosciences
Our research is focussed on how the heart forms during embryonic development, using zebrafish as a model organism. We are particularly interested in how specific ECM composition drives distinct aspects of cardiac morphogenesis, using a combination of genome-editing, live light sheet microscopy, and quantitative image analysis.
email: e.s.noel@sheffield.ac.uk
Dr Buddhapriya Chakrabarti, Physics and Astronomy
Dr Buddhapriya Chakrabarti, Physics and Astronomy
Biological systems are composed of soft, pliant structures, that driven away from their thermodynamic equilibrium state and acted on by non-linear feedback mechanisms. We employ analytical and numerical techniques rooted in classical statistical mechanics of soft materials to address, structure, mechanics, and hence function of biophysical systems. Our research interests encompass chromosome organisation in the cell nucleus, wetting and adhesion, and nonlinear mechanics of active filamentous shells.
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