Unlock Spatial Molecular Insights with DESI Mass Spectrometry Imaging

We are excited to offer Mass Spectrometry Imaging (MSI) using the state-of-the-art DESI XS source coupled with the SYNAPT XS High Definition Mass Spectrometer—a powerful new tool now available to support your biological research.

Desorption Electrospray Ionization (DESI) MSI is a cutting-edge technique that allows for the label-free detection and spatial mapping of molecules directly from tissue sections and other surfaces—without the need for complex sample preparation or matrix application. Operating under ambient conditions, DESI enables sensitive and high-resolution imaging of a wide range of biomolecules, including lipids, metabolites, and small molecules, with spatial resolution down to ~10 μm.

Our system combines:

• DESI XS Source: Enables gentle ionization from sample surfaces, preserving native molecular distribution while delivering high spatial resolution.

• SYNAPT XS Mass Spectrometer: Equipped with both Time-of-Flight (TOF) and Ion Mobility Separation (IMS), it provides broad mass range detection and resolves isomeric species that are indistinguishable by mass alone.

• HDI Software: Generates high-quality spatial images of drugs, metabolites, and lipids across tissues, supports comparison between normal and diseased samples, and aids in identifying novel molecular markers and signaling molecules.

Whether you're investigating tissue heterogeneity, biomarker localization, drug distribution, or microenvironmental changes, DESI-MSI offers unparalleled capability to visualize molecular landscapes in biological and clinical samples.

Let us help you add a new dimension to your research—literally.

👉 Contact us to learn how DESI-MSI can be integrated into your study.