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Analysis of experimental data and design of relationship in life science
Let's examine the data thoroughly and find out its essence.
We have been meticulously analyzing biological experimental data and providing feedback for quantitative mathematical modeling and experimental design. We re-launched as the "Data-Driven Biology" laboratory in April 2021, which is a field that considers and provides what is necessary to analyze experimental data, rather than relying solely on AI or mathematical models. Our approach involves pre-processing the data using our domain knowledge in biology, and then using machine learning and mathematical models to gain knowledge. We take pleasure in designing relational equations that represent biological functions based on physical constraints and laws derived from experimental data.
What's New
What's New
250428: New students have joined our lab.
250305: Ohkubo's paper on hybrid bioprocess control was entered into the “Cell & Molecular Biology Top 100 of 2024” in Sci Rep.
250218: A paper by Kenta T. Suzuki on the nationwide analysis of vascular access dysfunction in hemodialysis patients using NDB open data has been accepted in Scientific Reports.
241227: In collaboration with the Sasai Lab at NAIST, we identified TMEM196, a novel membrane protein regulating cell proliferation in the chicken embryo floor plate. This work has been accepted in Development, Growth & Differentiation. Xing Chen contributed through gene expression analysis.
241011: Tomoki Ohkubo's paper on hybrid bioprocess control using intracellular sensor molecules to correct mathematical model errors has been accepted for publication in Scientific Reports.
241002: Kenta T. Suzuki's paper, which demonstrates regional disparities in advanced treatments for kidney disease patients using NDB open data, has been accepted for publication in the Journal of Nursing Science and Engineering.
241001: We welcomed new members to our lab.
240916: We held a lab retreat at Univ of Fukui.
240619: Projects page has been updated.
240531: Placed the codes for Bayesian traction force estimation and neuronal polarization in the Software site.
240426: We welcomed new members to our lab.
240401: Dr. Yukihiro Suzuki (NAIST Ikeda Lab. graduate) has joined as a visiting assistant professor.
231104: Tomoki Okubo's paper on solving problems in optimization of biopharmaceutical production with nonlinear control has been accepted by New Generation Computing.
231101: Ryosuke Fujikawa's (now at Accenture) paper on traction force estimation introducing cell boundaries as a prior distribution has been accepted by Biophysical Journal. This is a collaborative research with Yamaguchi University.
231020: Collaborative research paper on regulation of genomic structure during differentiation of undifferentiated cells into neural ectoderm has been accepted for publication in iScience. Asst. Prof. Kogaji contributed to the data analysis.
231014: A review on the analysis of Rho GTPase activity and cell motility has been accepted by the Journal of Biomechanical Science and Engineering.
231012: We welcomed a new member to our lab.
230906: Tomoki Ohkubo's paper on the collaborative use of microorganisms and computers to boost the efficiency of valuable substance production has been accepted for publication in Scientific Reports. This research is a joint effort with Fujita Health University and Kyushu University.
230807: We held a lab retreat at Amanohashidate.
230427: We welcomed a new member to our lab.
230407: Our research paper on early discrimination of volatile organic compounds by multiple sensors has been accepted for publication in Sensors and Actuators B: Chemical . This is a joint research with National Institute of Advanced Industrial Science and Technology (AIST).
230209: Our research paper on decoding Rho GTPase activity to cell edge motility has been accepted for publication in Cell Reports. This is a joint effort with Fujita Health University, Tokyo University of Science, and National Institute for Basic Biology.
220812: Assistant Professor Toshiya Kogaji's paper has been accepted for publication in Scientific reports.
220808: We held a lab retreat at Himaka Island.
220807: Assistant Professor Toshiya Kogaji's review article has been accepted for publication in Current Opinion in Endocrine and Metabolic Research.
220429: We welcomed a new member to our lab.
211201: Tatsuya Yamada was appointed as a visiting assistant professor.
211008: Our joint research with Inagaki Lab. was accepted for publication in the Journal of Visualized Experiments. Mr. Fujikawa contributed to the creation of an easy-to-use cell force estimation software.
211001: We welcomed a new member to our lab.
210810: We held a lab retreat on NAIST campus.
210501: We welcomed a new member to our lab.
210401: Assistant Professor Toshiya Kogajiri joined our lab.
210401: Our lab has been renamed the "Data-Driven Biology" at The Data Sciennce Center, NAIST.
210331: Assistant Professor Katsuyuki Kunita left our lab and joined Fujita Health University.
8916-5 Takayama Ikoma Nara, 6300192, Japan
Laboratory of Data-Driven Biology (Sakumura Lab)
Data Science Center & Division of Biological Science
Nara Institute of Science and Technology
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