We focuse on understanding how single cells adapt to stress in complex biological systems. We develop microfluidic and bioelectronic platforms that enable precise control and quantitative measurement of cellular responses to chemical, physical, and biological stressors relevant to infection and cancer.
Our research is driven by the idea that cell-to-cell heterogeneity plays a critical role in treatment response, disease progression, and therapeutic resistance. By combining single-cell microengineering, dielectrophoresis, live-cell imaging, and advanced analytical methods, we aim to reveal mechanistic principles that govern cellular adaptation under stress.
A central goal of our lab is to bridge engineering and life sciences. We work at the interface of microfluidics, biophysics, and pharmaceutical biology, transforming engineered systems into tools for fundamental biological discovery. Our platforms allow us to interrogate microbial persistence under antibiotic pressure, cancer–immune interactions within engineered microenvironments, and stress-induced phenotypic changes that can be exploited for diagnostics.
Our lab maintains strong international collaborations and an interdisciplinary research culture. We are committed to training the next generation of scientists in quantitative thinking, experimental rigor, and cross-disciplinary communication. We welcome motivated students and researchers from engineering, biology, and medicine who are interested in single-cell analysis and microengineered biological systems.