Publications

Articles

47. C. J. Richards, T. C. Q. Burgers, R. Vlijm, W. H. Roos & C. Åberg. Rapid internalization of nanoparticles by human cells at the single particle level. ACS Nano 17, 16517–16529 (2023). doi:10.1021/acsnano.3c01124

46. B. Yang, C. J. Richards, T. B. Gandek, I. de Boer, I. Aguirre-Zuazo, E. Niemeijer & C. Åberg. Following nanoparticle uptake by cells using high-throughput microscopy and the deep-learning based cell identification algorithm Cellpose. Frontiers in Nanotechnology 5, 1181362 (2023). doi:10.3389/fnano.2023.1181362

45. B. Corci, O. Hooiveld, A. M. Dolga & C. Åberg. Extending the analogy between intracellular motion in mammalian cells and glassy dynamics. Soft Matter 19, 2529–2538 (2023). doi:10.1039/D2SM01672A

44. C. J. Richards, M. Ahmadi, M. C. A. Stuart, B. J. Kooi, C. Åberg & W. H. Roos. The effect of biomolecular corona on adsorption onto and desorption from a model lipid membrane. Nanoscale 15, 248–258 (2023). doi:10.1039/D2NR05296B

43. Z. Izzah, T. R. Zijp, C. Åberg, D. J. Touw & J. F. van Boven. Electronic smart blister packages to monitor and support medication adherence: A usability study. Patient Preference and Adherence 16, 2543–2558 (2022). doi:10.2147/PPA.S374685

42. I. de Boer, C. J. Richards & C. Åberg. Simultaneous exposure of different nanoparticles influences cell uptake. Pharmaceutics 14, 136 (2022). doi:10.3390/pharmaceutics14010136

41. T. R. Zijp, Z. Izzah, C. Åberg, C. T. Gan, S. J. L. Bakker, D. J. Touw & J. F. M. van Boven. Clinical value of emerging bioanalytical methods for drug measurements: A scoping review of their applicability for medication adherence and therapeutic drug monitoring. Drugs 81, 1983–2002 (2021). doi:10.1007/s40265-021-01618-7

40. C. Åberg, V. Piattelli, D. Montizaan & A. Salvati. Sources of variability in nanoparticle uptake by cells. Nanoscale 13, 17530–17546 (2021). doi:10.1039/D1NR04690J

39. C. Åberg & A. Robinson. Single-molecule localisation microscopy: Accounting for chance co-localisation between foci in bacterial cells. European Biophysics Journal 50, 941–950 (2021). doi:10.1007/s00249-021-01555-z

38. N. Vtyurina, C. Åberg & A. Salvati. Imaging of nanoparticle uptake and kinetics of intracellular trafficking in individual cells. Nanoscale 13, 10436–10466 (2021). doi:10.1039/D1NR00901J

37. C. Åberg & B. Poolman. Glass-like characteristics of intracellular motion in human cells. Biophysical Journal 120, 2355–2366 (2021). doi:10.1016/j.bpj.2021.04.011

36. C. Åberg. Kinetics of nanoparticle uptake into and distribution in human cells. Nanoscale Advances 3, 2196–2212 (2021). doi:10.1039/D0NA00716A

35. T. Lijster & C. Åberg. Asymmetry of nanoparticle inheritance upon cell division: Effect on the coefficient of variation. PLOS ONE 15, e0242547 (2020). doi:10.1371/journal.pone.0242547

34. R. Bartucci, C. Åberg, B. N. Melgert, Y. L. Boersma, P. Olinga & A. Salvati. Time-resolved quantification of nanoparticle uptake, distribution, and impact in precision-cut liver slices. Small 16, 1906523 (2020). doi:10.1002/smll.201906523

33. A. Salvati, I. Nelissen, A. Haase, C. Åberg, S. Moya, A. Jacobs, F. Alnasser, T. Bewersdorff, S. Deville, A. Luch & K. A. Dawson. Quantitative measurement of nanoparticle uptake by flow cytometry illustrated by an interlaboratory comparison of the uptake of labelled polystyrene nanoparticles. NanoImpact 9, 42–50 (2018). doi:10.1016/j.impact.2017.10.004

32. K. Prapainop, R. Miao, C. Åberg, A. Salvati & K. A. Dawson. Reciprocal upregulation of scavenger receptors complicates interpretation of nanoparticle uptake in non-phagocytic cells. Nanoscale 9, 11261–11268 (2017). doi:10.1039/C7NR03254D

31. D. Ye, M. Bramini, D. R. Hristov, S. Wan, A. Salvati, C. Åberg & K. A. Dawson. Low uptake of silica nanoparticles in Caco-2 intestinal epithelial barriers. Beilstein Journal of Nanotechnology 8, 1396–1406 (2017). doi:10.3762/bjnano.8.141

30. C. Åberg, J. A. Kim, A. Salvati & K. A. Dawson. Reply to ‘The interface of nanoparticles with proliferating mammalian cells’. Nature Nanotechnology 12, 600–603 (2017). doi:10.1038/nnano.2017.139

29. B. Liu, C. Åberg, F. J. van Eerden, S. J. Marrink, B. Poolman & A. J. Boersma. Design and properties of genetically encoded probes for sensing macromolecular crowding. Biophysical Journal 112, 1929–1939 (2017). doi:10.1016/j.bpj.2017.04.004

28. C. Åberg, J. A. Varela, L. W. Fitzpatrick & K. A. Dawson. Spatial and structural metrics for living cells inspired by statistical mechanics. Scientific Reports 6, 34457 (2016). doi:10.1038/srep34457

27. R. L. Marchese Robinson, I. Lynch, W. Peijnenburg, J. Rumble, F. Klaessig, C. Marquardt, H. Rauscher, T. Puzyn, R. Purian, C. Åberg, S. Karcher, H. Vriens, P. Hoet, M. Hoover, C. Hendren & S. Harper. How should the completeness and quality of curated nanomaterial data be evaluated? Nanoscale 8, 9919–9943 (2016). doi:10.1039/C5NR08944A

26. C. Åberg, K. E. Duderstadt & A. M. van Oijen. Stability versus exchange: a paradox in DNA replication. Nucleic Acids Research 44, 4846–4854 (2016). doi:10.1093/nar/gkw296

25. C. Åberg. Quantitative analysis of nanoparticle transport through in vitro blood-brain barrier models. Tissue Barriers 4, e1143545 (2016). doi:10.1080/21688370.2016.1143545

24. P. M. Kelly, C. Åberg, E. Polo, A. O’Connell, J. Cookman, J. Fallon, Ž. Krpetić & K. A. Dawson. Mapping protein binding sites on the biomolecular corona of nanoparticles. Nature Nanotechnology 10, 472–479 (2015). doi:10.1038/nnano.2015.47

23. J. A. Varela, C. Åberg, J. C. Simpson & K. A. Dawson. Trajectory-based co-localization measures for nanoparticle-cell interaction studies. Small 11, 2026–2031 (2015). doi:10.1002/smll.201401849

22. J. A. Kim, A. Salvati, C. Åberg & K. A. Dawson. Suppression of nanoparticle cytotoxicity approaching in vivo serum concentrations: Limitations of in vitro testing for nanosafety. Nanoscale 6, 14180–14184 (2014). doi:10.1039/c4nr04970e

21. M. Bramini, D. Ye, A. Hallerbach, M. Nic Raghnaill, A. Salvati, C. Åberg & K. A. Dawson. Imaging approach to mechanistic study of nanoparticle interactions with the blood-brain barrier. ACS Nano 8, 4304–4312 (2014). doi:10.1021/nn5018523

20. M. Nic Raghnaill, M. Bramini, D. Ye, P.-O. Couraud, I. A. Romero, B. Weksler, C. Åberg, A. Salvati, I. Lynch & K. A. Dawson. Paracrine signalling of inflammatory cytokines from an in vitro blood brain barrier model upon exposure to polymeric nanoparticles. Analyst 139, 923–930 (2014). doi:10.1039/C3AN01621H

19. D. Ye, M. Nic Raghnaill, M. Bramini, E. Mahon, C. Åberg, A. Salvati & K. A. Dawson. Nanoparticle accumulation and transcytosis in brain endothelial cell layers. Nanoscale 5, 11153–11165 (2013). doi:10.1039/C3NR02905K

18. J. A. Kim, C. Åberg, G. de Cárcer, M. Malumbres, A. Salvati & K. A. Dawson. Low dose of amino-modified nanoparticles induces cell cycle arrest. ACS Nano 7, 7483–7494 (2013). doi:10.1021/nn403126e

17. C. Åberg, J. A. Kim, A. Salvati & K. A. Dawson. Theoretical framework for nanoparticle uptake and accumulation kinetics in dividing cell populations. EPL (Europhysics Letters) 101, 38007 (2013). doi:10.1209/0295-5075/101/38007

16. A. Salvati, A. S. Pitek, M. P. Monopoli, K. Prapainop, F. Baldelli Bombelli, D. R. Hristov, P. M. Kelly, C. Åberg, E. Mahon & K. A. Dawson. Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface. Nature Nanotechnology 8, 137–143 (2013). doi:10.1038/nnano.2012.237

15. A. Lesniak, A. Salvati, M. J. Santos-Martinez, M. W. Radomski, K. A. Dawson & C. Åberg. Nanoparticle adhesion to the cell membrane and its effect on nanoparticle uptake efficiency. Journal of the American Chemical Society 135, 1438–1444 (2013). doi:10.1021/ja309812z

14. C. Åberg, E. Sparr & H. Wennerström. Lipid phase behaviour under steady state conditions. Faraday Discussions 161, 151–166 (2013). doi:10.1039/C2FD20079A

13. M. P. Monopoli, C. Åberg, A. Salvati & K. A. Dawson. Biomolecular coronas provide the biological identity of nanosized materials. Nature Nanotechnology 7, 779–786 (2012). doi:10.1038/nnano.2012.207

12. J. A. Varela, M. Bexiga, C. Åberg, J. C. Simpson & K. A. Dawson. Quantifying size-dependent interactions between fluorescently labeled polystyrene nanoparticles and mammalian cells. Journal of Nanobiotechnology 10, 39 (2012). doi:10.1186/1477-3155-10-39

11. A. Lesniak, F. Fenaroli, M. P. Monopoli, C. Åberg, K. A. Dawson & A. Salvati. Effects of the presence or absence of a protein corona on silica nanoparticle uptake and impact on cells. ACS Nano 6, 5845–5857 (2012). doi:10.1021/nn300223w

10. J. A. Kim, C. Åberg, A. Salvati & K. A. Dawson. Role of cell cycle on the cellular uptake and dilution of nanoparticles in a cell population. Nature Nanotechnology 7, 62–68 (2012). doi:10.1038/nnano.2011.191

9. P. Falkman, C. Åberg, A. Clemens & E. Sparr. Lyotropic lipid phases confined in cylindrical pores: structure and permeability. Journal of Physical Chemistry B 115, 14450–14461 (2011). doi:10.1021/jp206451c

8. A. Salvati, C. Åberg, T. dos Santos, J. Varela, P. Pinto, I. Lynch & K. A. Dawson. Experimental and theoretical comparison of intracellular import of polymeric nanoparticles and small molecules: Toward models of uptake kinetics. Nanomedicine: Nanotechnology, Biology and Medicine 7, 818–826 (2011). doi:10.1016/j.nano.2011.03.005

7. C. Åberg, E. Sparr, M. Larsson & H. Wennerström. A theoretical study of diffusional transport over the alveolar surfactant layer. Journal of The Royal Society Interface 7, 1403–1410 (2010). doi:10.1098/rsif.2010.0082

6. E. Sparr, C. Åberg, P. Nilsson & H. Wennerström. Diffusional transport in responding lipid membranes. Soft Matter 5, 3225–3233 (2009). doi:10.1039/b901737b

5. C. Åberg, E. Sparr, K. J. Edler & H. Wennerström. Nonequilibrium phase transformations at the air-liquid interface. Langmuir 25, 12177–12184 (2009). doi:10.1021/la900867k

4. C. Åberg & H. Wennerström. Coupled transport processes in responding membranes: The case of a single gradient. Physical Chemistry Chemical Physics 11, 9075–9081 (2009). doi:10.1039/b909187d

3. C. Åberg, H. Wennerström & E. Sparr. Transport processes in responding lipid membranes: A possible mechanism for the pH gradient in the stratum corneum. Langmuir 24, 8061–8070 (2008). doi:10.1021/la800543r

2. C. Åberg, C. Pairin, F. O. Costa-Balogh & E. Sparr. Responding double-porous lipid membrane: Lyotropic phases in a polymer scaffold. Biochimica et Biophysica Acta (BBA) - Biomembranes 1778, 549–558 (2008). doi:10.1016/j.bbamem.2007.10.020

1. F. O. Costa-Balogh, C. Åberg, J. J. S. Sousa & E. Sparr. Drug transport in responding lipid membranes can be regulated by an external osmotic gradient. Langmuir 21, 10307–10310 (2005). doi:10.1021/la051947n

Published abstracts

7. R. B. Lira, C. Richards, R. R. M. Cavalcanti, C. Aberg, K. A. Riske & W. H. Roos. Fusion modifies the material properties of membranes. Biophysical Journal 122, 176a (2023). doi:10.1016/j.bpj.2022.11.1094

6. Z. Izzah, T. P. Asmarawati, B. Suprapti, C. Åberg & D. J. Touw. Adherence to antiretroviral therapy and treatment outcomes among HIV-positive adults in Indonesia: A cross-sectional study. International Journal of Clinical Pharmacy 45, 254 (2023). doi:10.1007/s11096-023-01537-5

5. T. R. Zijp, Z. Izzah, C. Åberg, C. T. Gan, S. J. L. Bakker, D. J. Touw & J. F. M. van Boven. Emerging bioanalytical methods for drug monitoring in patients receiving chronic drug therapies: a scoping review. International Journal of Clinical Pharmacy 44, 285 (2022). doi:10.1007/s11096-021-01373-5

4. R. Bartucci, C. Åberg, Y. L. Boersma, P. Olinga & A. Salvati. Precision-cut liver slices as a promising ex vivo model for nanosafety studies. Toxicology Letters 314, S204–S205 (2019). doi:10.1016/j.toxlet.2019.09.002

3. A. Boersma, B. Liu, C. Aberg & B. Poolman. Quantification of macromolecular crowding in living cells. Biophysical Journal 110, 368a (2016). doi:10.1016/j.bpj.2015.11.1984

2. F. McDermott, M. Bramini, A. Rogers, C. Aberg, K. Dawson, D. Winter & A. Baird. Polyamines induce a morphological effect on colonic mucus, as seen by the movement of nanoparticles through gel layers. Irish Journal of Medical Science 184, S25 (2015).

1. F. McDermott, A. Rogers, M. Bramini, L. Fitzpatrick, C. Aberg, K. Dawson, A. Baird & D. Winter. The use of nanoparticles to investigate the interaction of polyamines and colonic mucus barrier function. International Journal of Surgery 12, S14 (2014). doi:10.1016/j.ijsu.2014.07.027

Book chapter

1. M. P. Monopoli, C. Aberg, A. Salvati & K. A. Dawson. Biomolecular coronas provide the biological identity of nanosized materials. in Nano-enabled medical applications (ed. Balogh, L. P.) 205–230 (Jenny Stanford Publishing, 2019). doi:10.1201/9780429399039