Discovery of the cell
The first time the word cell was used to refer to these tiny units of life was in 1665 by a British scientist named Robert Hooke. Hooke was one of the earliest scientists to study living things under a microscope. The microscopes of his day were not very strong, but Hooke was still able to make an important discovery. When he looked at a thin slice of cork under his microscope, he was surprised to see what looked like a honeycomb. Hooke made the drawing in the Figure to show what he saw. As you can see, the cork was made up of many tiny units, which Hooke called cells.
Leeuwenhoek’s Discoveries
Soon after Robert Hooke discovered cells in cork, Anton van Leeuwenhoek in Holland made other important discoveries using a microscope. Leeuwenhoek made his own microscope lenses, and he was so good at it that his microscope was more powerful than other microscopes of his day. In fact, Leeuwenhoek’s microscope was almost as strong as modern light microscopes.
Using his microscope, Leeuwenhoek discovered tiny animals such as rotifers. The magnified image of a rotifer in the Figure is similar to what Leeuwenhoek observed. Leeuwenhoek also discovered human blood cells. He even scraped plaque from his own teeth and observed it under the microscope. What do you think Leeuwenhoek saw in the plaque? He saw tiny living things with a single cell that he named animalcules (“tiny animals”). Today, we call Leeuwenhoek’s animalcules bacteria.
By the early 1800s, scientists had observed the cells of many different organisms. These observations led two German scientists, named Theodor Schwann and Matthias Jakob Schleiden, to propose that cells are the basic building blocks of all living things. Around 1850, a German doctor named Rudolf Virchow was studying cells under a microscope when he happened to see them dividing and forming new cells. He realized that living cells produce new cells through division. Based on this realization, Virchow proposed that living cells arise only from other living cells.
The ideas of all three scientists—Schwann, Schleiden, and Virchow—led to the cell theory, which is one of the fundamental theories of biology. The cell theory states that:
All organisms are made of one or more cells.
All the life functions of organisms occur within cells.
All cells come from already existing cells
The wacky history of cell theory
Mr. Tamez: The Cell Theory Song
Although cells are diverse, all cells have certain parts in common. The parts include a plasma membrane, cytoplasm, ribosomes, and DNA.
The plasma membrane (also called the cell membrane) is a thin coat of lipids that surrounds a cell. It forms the physical boundary between the cell and its environment, so you can think of it as the “skin” of the cell.
Cytoplasm refers to all of the cellular material inside the plasma membrane. Cytoplasm is made up of a watery substance called cytosol and contains other cell structures such as ribosomes.
Ribosomes are structures in the cytoplasm where proteins are made.
DNA is a nucleic acid found in cells. It contains the genetic instructions that cells need to make proteins.
These parts are common to all cells, from organisms as different as bacteria and human beings. How did all known organisms come to have such similar cells? The similarities show that all life on Earth has a common evolutionary history.
Prokaryotic cells are cells without a nucleus. The DNA in prokaryotic cells is in the cytoplasm rather than enclosed within a nuclear membrane. Prokaryotic cells are found in single-celled organisms, such as bacteria, like the one shown in Figure. Organisms with prokaryotic cells are called prokaryotes. They were the first type of organisms to evolve and are still the most common organisms today.
Eukaryotic cells are cells that contain a nucleus. A typical eukaryotic cell is shown in the Figure. Eukaryotic cells are usually larger than prokaryotic cells, and they are found mainly in multicellular organisms. Organisms with eukaryotic cells are called eukaryotes, and they range from fungi to people.
Eukaryotic cells also contain other organelles besides the nucleus. An organelle is a structure within the cytoplasm that performs a specific job in the cell. Organelles called mitochondria, for example, provide energy to the cell, and organelles called vacuoles store substances in the cell. Organelles allow eukaryotic cells to carry out more functions than prokaryotic cells can.