Engineered inducible gene expression systems in iPSCs to drive differentiation into dendritic cells, combining molecular biology and synthetic biology approaches to explore new frontiers in immune cell therapy. Optimized experimental conditions and used qPCR and imaging to evaluate the success of genetic circuits, contributing to foundational work in cell-based immunotherapies.
Studied dendritic cell immune responses under simulated microgravity, managing 3D cultures and using flow cytometry to investigate how altered physical environments influence immune function. Advanced the understanding of immune cell behavior in extreme environments—findings relevant not only to space biology but also to stress-adaptive immunity in clinical settings.
Investigated the role of 5-HT4 receptors in gut-brain communication within the enteric nervous system using immunohistochemistry and advanced imaging techniques. Applied computational tools like Cellpose for high-accuracy cell segmentation, contributing to a more nuanced understanding of neurochemical signaling pathways relevant to mental health and gastrointestinal disorders.