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Our research group is interested in the areas of cell biology, genetic, molecular and cellular toxicology. We particularly focus on investigating the basic biology and with the physiological, pharmacological, and toxic response of cellular systems. The experiments includes studies of subcellular and cellular systems derived from eukaryotic cell types and animal studies. Currently, our research include:
- Preparation and evaluation of in vitro 3D culture of human hepatocytes as a model for application in drug-induced hepatotoxic screening.
- Prediction of drug induced liver injury using molecular and biological descriptors
- Bacopa monnieri extract affects major cytochrome P450 mRNA expression and monooxygenase activities in human hepatocyte cultures.
- An in vitro, herb-drug interaction study of Thai herbal medicine: Inhibition potential on drug-metabolizing enzymes
- Isolation, purification and structure elucidation of bioactive compounds of Actinobacteria from forest soil of Nam Nao national park in Thailand
- Performance of human hepatocytes in suspension under shaking conditions for clearance predictions, competitive CYP450 inhibition and comparison with microsomes and hepatocyte monolayers
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