Research

Our group is interested in the total synthesis of bioactive natural products and biologically relevant molecules. We strive to design practical and efficient synthetic routes for the construction of these natural products and related analogs.

The ultimate goal is to take advantage of nature's vast chemical diversity to answer critical questions in chemical biology and medicinal chemistry.

Within the realm of academic research, we aspire to use natural products and derivatives as molecular probes, to increase the current understanding of the processes of disease inception, progression and therapy-resistance development.

Another theme in our research involves the development of practical synthetic methodologies that will allow access to natural and non-natural compounds and building blocks in a chemo- regio- and stereoselective fashion. Of particular interest are the development of ligand-transition metal and organocatalytic systems as a way to rapidly generate chemical complexity.

Please see our publications page for more information.