Publications

Publications from NIPER Guwahati

2025

• 34) L. Sheeba, N. Sudheer, R. Khanra, Saigal, K. Seth.*  “Facile chemodivergent synthesis of fused indolo[2,3‑b]quinoxalines and benzo[4,5]imidazo[1,2‑c]quinazolin-6(5H)‑ones: An organocatalytic trifluoromethanesulfonic acid-controlled mechanistic switch between condensation and ring expansion of the isatin core.” ACS Omega 2025, DOI: 10.1021/acsomega.5c10483. IF 3.600  [DOI: 10.1021/acsomega.5c10483] (An invited contribution).

• 33) Saigal, M. Maingle, S. Prajapati, N. Sharma, J. Acharya, K. Seth.*  “Natural biodegradable lemon juice-catalyzed one-pot pseudo four-component synthesis of functionally rich 4,5-dihydro‑1H‑pyrrol-5-ols and 1,4-dihydropyridines: Quantity of reaction components and their addition sequence determine selectivity switch between five- vs six-membered rings.” J. Org. Chem. 2025, DOI: 10.1021/acs.joc.5c02646. IF 3.600  [DOI: 10.1021/acs.joc.5c02646]

• 32) M. Maingle, Saigal, I. Icecreamwala, S. S. Madhukar, R. Khanra, K. Seth.*  “The Ru(II)-catalyzed catalytic additive-controlled selectivity switch between mono-olefination and dehydrogenative annulation of 3‑aryl-4(3H)‑quinazolinone: access to products of different chemotypes.” J. Org. Chem. 2025, DOI: 10.1021/acs.joc.5c02240. IF 3.600  [DOI: 10.1021/acs.joc.5c02240]

2024

• 31) Saigal, S. Sunny, K. Seth.*  “Lemon juice as a natural biodegradable catalyst for an ecofriendly one-pot pseudo-three-component synthesis of N,1-dimethyl-6-(methylsulfanyl)-3,5-dinitro-1,4-dihydropyridine-2-amines.” Synlett. 2025, 36, 2355-2363. IF 1.700  [DOI: 10.1055/a-2499-3563] (Part of the special issue on Emerging Trends in Organic Chemistry: A Focus on India).

• 30) Saigal, N. Sudheer, S. C. Sahoo, M. M. Khan, K. Seth.*  ““In-Water” three-component one-pot reaction for the facile synthesis of densely functionalized 2,3-dihydro-1H-pyrrol-2-ols and mechanistic insight.” ACS Sustainable Chem. Eng. 2024, 12, 13336-13351. IF 7.100  [DOI: 10.1021/acssuschemeng.4c05293]

• 29) P. Suryavanshi, S. Mahajan, S. K. Banerjee, K. Seth,*  S. Banerjee.* “Synthesis and characterization of a pH/temperature-dual responsive hydrogel with promising biocompatibility features for stimuli-responsive 5-FU delivery.” J. Mater. Chem. B 2024, 12, 5098-5110.  IF 7.000  [DOI: 10.1039/D4TB00168K] [marked as HOT paper!!!] (Part of the themed collections Journal of Materials Chemistry B HOT Papers and Journal of Materials Chemistry B Emerging Investigators 2024). 

• 28) S. Sunny,± M. Maingle,± L. Sheeba, F. R. Pathan, G. Sankar J., H. Juloori, S. G. Gadewar, K. Seth.*  “Cu(II)-catalyzed ‘in-water’ N-arylation of electron-deficient NH-heterocycles.” Green Chem. 2024, 26, 3149-3158. [± Equal contribution].  IF 9.800  [DOI: 10.1039/D3GC05163C]

• 27) S. Sunny, N. Sudheer, I. Icecreamwala, S. S. Madhukar, N. S. Sopan, S. K. Maio, G. Prashanth, K. Seth.* "Ru-catalyzed meta-selective aryl sp2C-H bond alkylation of biologically important heterocycles to access C-C bond." Book Chapter: D. Maiti and U. Sharma (Eds.), in Functionalisation of Heterocycles through Transition Metal Catalyzed C-H Activation in the book series ‘Topics in Heterocyclic Chemistry’ , 2024, 60, 33-60. Publisher: Springer Nature, Berlin, Germany. (ISBN No.: 978-3-031-70843-5). [DOI: 10.1007/7081_2024_67] 

2023

• 26) M. Maingle, S. Sunny, L. Sheeba, F. R. Pathan, K. Seth.*  “Benzoxazole or benzothiazole as an innate directing group for palladium- and ruthenium-catalyzed complementary C–H arylation: Functionalization of biorelevant heterocyclic scaffolds.” Synthesis 2024, 56, 312-328. IF 3.019  [DOI: 10.1055/a-2193-4804]

• 25) S. Sunny, M. Maingle, L. Sheeba, F. R. Pathan, G. Sankar J., H. Juloori, S. G. Gadewar, K. Seth.*  “Pd-nanoparticles-catalyzed C(sp2)–H arylation for the synthesis of functionalized heterocycles: Recent progress and prospects.” Synthesis 2024, 56, 611-638. IF 3.019  [DOI: 10.1055/a-2060-3488] (Part of the special topic on Synthetic Development of Key Intermediates and Active Pharmaceutical Ingredients (APIs)).

• 24) M. Maingle, S. Sunny, K. A. Ajinath, A. C. Tomy, W. K. Madanrao, P. T. Sree, K. Seth.* "Half-sandwich organo-group-3 metal-catalyzed C–C bond formation via sp2 C–H bond functionalization." Book Chapter: B. Basu and B. Banerjee (Eds.), in Rare Earth Elements: Processing, Catalytic Applications and Environmental Impact, 2023, 13-43. Publisher: Walter de Gruyter GmbH, 10785 Berlin, Germany. [ISBN No.: 978-3-11-078794-8] 

• 23) P. Suryavanshi, S. Kawre, M. Maniruzzaman, K. Seth,* S. Banerjee.* "Thermo-responsive self-folding feedstock with excellent shape memory programming.” Chem. Pap. 2023, 77, 3145-3154. IF 2.146  [DOI: 10.1007/s11696-023-02693-8] 

2022

• 22) S. Sunny, M. Maingle, K. Seth.*  “Advances in bifunctional squaramide-catalyzed asymmetric sulfa-Michael addition: A decade update.” Synlett. 2023, 34, 572-600. IF 2.206  [DOI: 10.1055/a-1921-0748] (Part of the special issue on Chemical Synthesis and Catalysis in India).

• 21) K. Seth.* “Recent progress in rare-earth metal-catalyzed sp2 and sp3 C–H functionalization to construct C–C and C–heteroelement bonds.” Org. Chem. Front. 2022, 9, 3102-3141. IF 5.456 [DOI: 10.1039/D1QO01859K]

2021

• 20) K. Seth.* “Innate directing group guided transition metal-catalyzed C(sp2)–H activation: Functionalization of biosignificant heterocyclic scaffolds.” Book Chapter: D. Maiti (Ed.), in Handbook of CH-Functionalization (CHF), 2022,  [DOI: 10.1002/9783527834242.chf0158]. Publisher: Wiley-VCH GmbH, Weinheim, Germany. [ISBN No.: 9783527834242]  

Publications from PhD/Post-Doc

2020

• 19) B. V. Pipaliya, K. Seth, A. K. Chakraborti. “Ruthenium(II)-catalyzed C(sp2 )–H bond alkenylation of 2-arylbenzo[d]oxazole and 2-arylbenzo[d]thiazole with unactivated olefins.” Chem. Asian J. 2021, 16, 87-96. (Appeared in ‘Hot Topic: C–H Activation’). IF 4.839 [DOI: 10.1002/asia.202001304]

2019

• 18) R. Kumar, N. Saha, P. Purohit, S. K. Garg, K. Seth, V. S. Meena, S. Dubey, K. Dave, R. Goyal, S. S. Sharma, U. C. Banerjee, A. K. Chakraborti. “Cyclic enaminone as new chemotype for selective cyclooxygenase-2 inhibitory, anti-inflammatory, and analgesic activities.” Eur. J. Med. Chem. 2019, 182, 111601. IF 7.088 [DOI: 10.1016/j.ejmech.2019.111601]

2018

• 17) B. Li, K. Seth, B. Niu, L. Pan, H. Yang, H. Ge, “Transient-ligand-enabled ortho-arylation of five-membered heterocycles: facile access to mechanochromic materials.” Angew. Chem. Int. Ed. 2018, 57, 3401-3405. (Highlighted in Synfacts 2018, 14, 0480). IF 16.823 [DOI: 10.1002/anie.201713357]

2017

• 16) A. Deb, S. Singh, K. Seth, S. Pimparkar, B. Bhaskararao, S. Guin, R. B. Sunoj, D. Maiti, “Experimental and computational studies on remote γ-C(sp3)–H silylation and germanylation of aliphatic carboxamides.” ACS Catal. 2017, 7, 8171-8175. IF 13.700 [DOI: 10.1021/acscatal.7b03056]

• 15) K. Seth, P. Purohit, A. K. Chakraborti, “Microwave assisted synthesis of biorelevant benzazoles.” Curr. Med. Chem. 2017, 24, 4638-4676. IF 4.740  [DOI: 10.2174/0929867323666161025142005]

• 14) K. Seth,# M. Bera, # M. Brochetta, S. Agasti, A. Das, A. Gandini, A. Porta, G. Zanoni, D. Maiti, “Incorporating unbiased, unactivated aliphatic alkenes in Pd(II)-catalyzed olefination of benzyl phosphonamide.” ACS Catal. 2017, 7, 7732-7736. [# Equal contribution]. IF 13.700 [DOI: 10.1021/acscatal.7b02394]

• 13) P. Purohit, K. Seth, A. Kumar, A. K. Chakraborti, “C–O bond activation by Nickel–Palladium hetero-bimetallic nanoparticles for Suzuki–Miyaura reaction of bioactive heterocycle-tethered sterically hindered aryl carbonates.” ACS Catal. 2017, 7, 2452-2457. (Highlighted in Synfacts 2017, 13, 0526). IF 13.700 [DOI: 10.1021/acscatal.6b02912]

2016

• 12) A. Dey, S. Sasmal, K. Seth, G. K. Lahiri, D. Maiti, “Nickel catalyzed deamidative step-down reduction of amides to aromatic hydrocarbons.” ACS Catal. 2017, 7, 433-437. IF 13.700 [DOI: 10.1021/acscatal.6b03040]

• 11) K. Seth, S. Raha Roy, A. Kumar, A. K. Chakraborti, “The palladium and copper contrast: a twist to products of different chemotypes and altered mechanistic pathways.” Catal. Sci. Technol. 2016, 6, 2892-2896. IF 6.177 [DOI: 10.1039/C6CY00415F] 

2015

• 10) N. Parikh, S. Raha Roy, K. Seth, A. Kumar, A. K. Chakraborti, “‘On-water’ multicomponent reaction for the diastereoselective synthesis of functionalized tetrahydropyridines and mechanistic insight.” Synthesis 2016, 48, 547-556. (Highlighted in ChemInform 2016, 48, DOI: 10.1002/chin.201628176 & Synfacts 2016, 12, 0453). IF 3.019 [DOI: 10.1055/s-0035-1561296]

• 9) K. Seth, S. Raha Roy, A. K. Chakraborti, “Synchronous double C–N bond formation via C–H activation for a novel synthetic route to phenazine.” Chem. Commun. 2016, 52, 922-925. IF 6.065 [DOI: 10.1039/C5CC08640J]

2014

• 8) K. Seth, M. Nautiyal, P. Purohit, N. Parikh, A. K. Chakraborti, “Palladium catalyzed C(sp2)–H activation for direct aryl hydroxylation: the unprecedented role of 1,4-dioxane as source of hydroxyl radical.” Chem. Commun. 2015, 51, 191-194. (Highlighted in ChemInform 2015, 46, DOI: 10.1002/chin.201522037). IF 6.065 [DOI: 10.1039/C4CC06864E]

• 7) K. Seth, S. Raha Roy, D. N. Kommi, B. V. Pipaliya, A. K. Chakraborti, “Silver nanoparticle-catalysed phenolysis of epoxides under neutral conditions: scope and limitations of metal nanoparticles and applications towards drug synthesis.” J. Mol. Catal. A: Chem. 2014, 392, 164-172. IF 5.089 [DOI: 10.1016/j.molcata.2014.05.011]

• 6) K. Seth, P. Purohit, A. K. Chakraborti, “Cooperative catalysis by palladium-nickel binary nanocluster for Suzuki-Miyaura reaction of ortho-heterocycle-tethered sterically hindered aryl bromides.” Org. Lett. 2014, 16, 2334-2337. (Highlighted in ChemInform 2014, 45, DOI: 10.1002/chin.201445144). IF 6.072 [DOI: 10.1021/ol500587m]

• 5) K. Seth, S. K. Garg, R. Kumar, P. Purohit, V. S. Meena, R. Goyal, U. C. Banerjee, A. K. Chakraborti, “2-(2-arylphenyl)benzoxazole as a novel anti-inflammatory scaffold: synthesis and biological evaluation.” ACS Med. Chem. Lett. 2014, 5, 512-516. IF 4.632 [DOI: 10.1021/ml400500e]

2013

• 4) D. Kumar, K. Seth, D. N. Kommi, S. Bhagat, A. K. Chakraborti, “Surfactant micelles as microreactors for the synthesis of quinoxalines in water: scope and limitations of surfactant catalysis.” RSC Adv. 2013, 3, 15157-15168. IF 4.056 [DOI: 10.1039/C3RA41038B]

• 3) K. Seth, S. Raha Roy, B. V. Pipaliya, A. K. Chakraborti, “Synergistic dual activation catalysis by palladium nanoparticles for epoxide ring opening with phenols.” Chem. Commun. 2013, 49, 5886-5888. (Highlighted in ChemInform 2013, 44, DOI: 10.1002/chin.201341056). IF 6.065 [DOI: 10.1039/C3CC42507J]  

• 2) D. N. Kommi, D. Kumar, K. Seth, A. K. Chakraborti, “Protecting group-free concise synthesis of (RS)/(S)-lubeluzole.” Org. Lett. 2013, 15, 1158-1161. IF 6.072 [DOI: 10.1021/ol302601b]

2011

• 1) S. Raha Roy, P. S. Jadhavar, K. Seth, K. K. Sharma, A. K. Chakraborti, “Organocatalytic application of ionic liquids: [bmim][MeSO4 ] as a recyclable organocatalyst in the multicomponent reaction for the preparation of dihydropyrimidinones and –thiones.” Synthesis 2011, 2261-2267. (Highlighted in ChemInform 2011, 42, DOI: 10.1002/chin.201147149). IF 3.019 [DOI: 10.1055/s-0030-1260067]

Patents

• 6) S. Kirubakaran, D. Khasa, K. Seth, L. Sheeba, S. S. Nandurkar. “Substituted 1,2,3-triazole compounds and a process for their preparation.” Indian Patent Application No. 202521070682, Date: July 24, 2025. (Applicant: IIT Gandhinagar). 

• 5) A. K. Chakraborti, P. Purohit, S. S. Sharma, K. Seth, S. B. Kharatmal, M. Singh, G. Kumar. “2-(2-Aryl/Alkylphenyl)benzazoles as selective COX-2 inhibitors.” Indian Patent Grant No. 387998, Grant Date: January 31, 2022; Application No. 2540/DEL/2015 Filed on 18th August 2015. (Applicant: NIPER S.A.S. Nagar).  

• 4) A. K. Chakraborti, K. Seth, S. Raha Roy, D. N. Kommi, “A green process for synthesis of β-hydroxy aryl ethers in presence of transition metal nanoparticles.” Indian Patent Grant No. 330000, Grant Date: January 22, 2020; Application No. 2071/DEL/2012 Filed on 3rd July 2012. (Applicant: NIPER S.A.S. Nagar). The patent has been selected for digital campaign on “Building Greener and Sustainable Punjab” by Punjab State Council for Science and Technology (PSCST) & Technology Innovation Support Centre (TISC) under ‘Mission Innovate Punjab’ to support and promote WIPO's campaign on “Green and Sustainable Future”.

• 3) A. K. Chakraborti, K. Seth, S. Raha Roy, D. N. Kommi, “Improved catalytic process for the synthesis of functionalized dibenzo[1,3]diazepines using metal nanoparticle based catalysts.” Indian Patent Grant No. 313508, Grant Date: May 31, 2019; Application No. 338/DEL/2014 Filed on 5th February 2014. (Applicant: NIPER S.A.S. Nagar). 

• 2) A. K. Chakraborti, D. Kumar, K. Seth, D. N. Kommi, “A green procedure for synthesis of functionalized quinoxaline compounds.” Indian Patent Grant No. 305259, Grant Date: January 02, 2019; Application No. 2023/DEL/2011 Filed on 18th July 2011. (Applicant: NIPER S.A.S. Nagar). 

• 1) A. K. Chakraborti, K. Seth, S. Raha Roy, “An improved process for synthesis of phenazines and azo compounds based on reusable metal nanoparticles as catalyst.” Indian Patent Grant No. 301751, Grant Date: October 01, 2018; Application No. 1818/DEL/2012 Filed on 13th June 2012. (Applicant: NIPER S.A.S. Nagar). 

Invited talks/lectures

• 4) July 3-5, 2025, Indian Institute of Technology Gandhinagar, Gujarat, India; 35th CRSI National Symposium in Chemistry and CRSI-ACS Lectures (CRSI NSC-35): ‘Click synthesis of 1,2,3-triazole derivatives in the pursuit of hit to potential lead compounds against prostate cancer.’ [IL-5]. 

• 3) March 25-27, 2022, Indian Institute of Technology Guwahati, Assam, India; Chemical Research Society of India 28th National Symposium in Chemistry (CRSI NSC-28): ‘Pd-Ag Binary Nanocluster-catalyzed Synchronous Double C-H Activation Accessing Phenazine Scaffold: Transition Metal Dependent Catalytic Switch Between Phenazine/Azoarene.’

• 2) July 2019, Indian Institute of Science Education and Research (IISER) Tirupati, Tirupati, India

• 1) July 2019, Department of Chemistry, Indian Institute of Technology (Banaras Hindu University) (IIT BHU), Varanasi, India. 

Poster/Oral presentations

• 4) September 4-6, 2024, Akal University, Talwandi Sabo, Punjab, India; International Conference on Recent Advances on Green Catalysis and Drug Discovery (ICRAGCDD-2024): L. Sheeba, and K. Seth.*  'Cu(II)-catalyzed N-arylation of electron-deficient NH-heterocycles ‘in-water’.' Oral presentation no. OP 64.

• 3) September 14-16, 2023, NIPER Hyderabad, Hyderabad, India; International Conference on New Horizons in Drugs, Devices & Diagnostics (NIPER Pharmacon–2023): S. Sunny, M. Maingle, and K. Seth.*  'Development of transition metal-catalyzed sustainable method for the synthesis of potential ulcerogenic wound healing agents.' Oral presentation no. OP 44. 

• 2) March 2-4, 2023, Department of Chemistry, North-Eastern Hill University, Shillong, India; International Symposium on Emerging Trends in Chemical Sciences (ETCS2023): M. Maingle, S. Sunny, and K. Seth.* ‘Ortho-selective arylation of 2-arylbenzoxazole/thiazole via transition metal-catalyzed C(sp2)-H activation.’  Poster no. PR 29.

• 1) November 10-12, 2022, NIPER, SAS Nagar, Punjab, India; International Symposium on Recent Trends and Future Opportunities in Pharmaceuticals (NIPER PHARMACON 2022): G. Sankar J., K. M. Wagh, and K. Seth,* ‘Synthesis and characterization of o-dephenyl ostarine as a reference standard in dope testing.’ Poster no. P2-1012.