About
About
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Education
Education
Ph.D. (Pharmaceutical Science) Birla Institute of Technology, Ranchi, India
M. Pharmacy (Pharmaceutical Chemistry) Birla Institute of Technology, Ranchi, India
B. Pharmacy Roland Institute of Pharmaceutical Sciences, Berhampur, India
12th (+2 Science) Jawahar Navodaya Vidyalaya, Balasore, India
10th (HSC) Jawahar Navodaya Vidyalaya, Balasore, India
Experience
Experience
Funder Director: June 2023 - Till Date - Dr. Sethi’s Laboratories Pvt. Lid., Guwahati, India
Assistant Professor: August 2020 - Till Date, National Institute of Pharmaceutical Education and Research, Guwahati, India
Senior Research Scientist: February 2016 - August 2020 (4 years 7 months) Trivedi SRL, Bhopal, and Thane, India
Scientist cum Plant Manager: December 2014 - January 2016 (1 year 2 months) Biotechayur Pvt. Ltd., Balasore, India
Institute Research Fellow: October 2011 - November 2014 (3 years 2 months) Dept. of Pharmaceutical Sciences and Technology, BIT, Mesra, Ranchi, India
Assistant Professor: July 2009 - September 2011 (2 years 3 months) GITAM Institute of Pharmacy, GITAM University, Visakhapatnam, India
Technical Skills
Technical Skills
Drug Discovery (Synthetic and Natural Products)
Computer Based Drug Design: SYBYL7.1 (QSAR, CoMFA and CoMSIA), Maestro 5.0 (SCHRODINGER) (Docking and QSAR study), Autodock-4 (Docking), Sequence alignment, UCSF Chimera, Chem. sk. and Chem 3D Ultra.
Natural Product Chemistry: Extraction, isolation, purification, and Characterization of Active Pharmaceutical Ingredients from natural sources i.e., Hydroxy citric acid, Curcumin, Gyminic acid, Glucosamine, Lutein, etc.
Management of Herbal extraction and manufacturing units, API production & Formulation in commercial scale bulk quantities from natural resources, writing of COA, SOP, BMR, export of product, etc.
Working knowledge of various industrial scale manufacturing instruments like Spray Dryer, Tray Dryer, Extractor, Evaporator, Shifter, Hammer mill, Grinder, Pulverizer, Blender, etc.
Technology transfer from research and development laboratory to commercial scale manufacturing unit.
Working knowledge in synthetic organic chemistry with characterization by LC-MS, GC-MS, NMR, PXRD, Particle size analysis, DSC, TGA/DTG, UV-Vis, and CHNSO of synthetic/natural organic/inorganic product and analysis.
Analytical and Bio-analytical study protocols design and development of nutraceuticals and pharmaceuticals.
Well-versed with the use of various Analytical Instruments such as LC-MS, UV-visible spectroscopy, FT-IR, DSC, TGA, CHNSO, Dissolution apparatus, Microwave Synthesizer, Paper and Column Chromatography.
Human Carbonic Anhydrase Inhibition (hCAI) Assay, Antimicrobial, and Animal study.
Indian & International Science Academic Honours
Indian & International Science Academic Honours
BIRAC-Biotechnology Ignition Grant (BIG): 50 Lakhs -2023
Member in Professional Bodies Indian Pharmacy Graduates Association (IPGA), India Pharmaceutical Society, B. I. T. Mesra, Ranchi.
Editorial Board Assistant Editor in “Journal of Global Trends in Pharmaceutical Sciences” Editorial Board Member in “EC Pharmacology and Toxicology”
Reviewer in International Journals Bioorganic & Medicinal Chemistry (Elsevier/Science Direct); Bioorganic & Medicinal Chemistry Letters (Elsevier/Science Direct); Arabian Journal of Chemistry (Elsevier/Science Direct); Letters in Drug Design & Discovery (Bentham Science); Journal of Enzyme Inhibition and Medicinal Chemistry (Informa Health Care); Sensors and Materials (An International Journal on Sensor Technology); Journal of Medicinal Plant Research (Academic Journals); Studies in Natural Products Chemistry (Elsevier/Science Direct); Organic & Biomolecular Chemistry (Royal Society of Chemistry), etc.
Patent
Patent
Sethi KK, Verma SM. 4,5,6,7-tetrachloro-1,3-dioxoisoindolin-2-yl benzenesulfonamide derivatives. Ref. no.: E-2/2088/2013-KOL, Application no. 568/KOL/2013. Indian Patent office, at Kolkata, India. (Published)
Sethi KK. Active human Carbonic Anhydrase Inhibitors (hCAIs) benzenesulfonamide compounds. Ref. no.: E-12/134/2021/KOL, Application no. 202131017895. Indian Patent office, at Kolkata, India. (Complete Specification Filed)
Process to prepare octopamine sulfate. Patent Application No. 202231000058. Indian Patent office, at Kolkata, India. (Complete Specification Filed)
Methods for preparation of Lutein from marigold flowers. Patent Application No. 202231062144. Indian Patent office, at Kolkata, India. (Complete Specification Filed)
Method for preparation of highly pure curcumin, desmethoxycurcumin, and bisdemethoxycurcumin from Lakadong, Patent Application No. 202231066460. Indian Patent office, at Kolkata, India. (Complete Specification Filed)
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