Publications
Publications
Viji Vijayan, Ibrar Ahmad Siddique, Sakshi Gupta, Evanka Madan Chopra, Navya Raj, Avadhesha Surolia, Sarika Gupta* (2025). Osteocalcin modulates Abeta42 aggregation to aid in amyloid reduction in mouse models of Alzheimer's disease. Experimental Neurology (in press) https://doi.org/10.1016/j.expneurol.2025.115322
Prabhat Upadhyay, Sudhir, Tarun, Sarika Gupta* (2025). Gut Microbiome Rewiring via Fecal Transplants: Uncovering Therapeutic Avenues in Murine Disease Models. BMC Neuroscience (in Press)
Leena Sapra, Chaman Saini, Pradyumna K. Mishra, Bhavuk Garg, Sarika Gupta, Vikrant Manhas & Rupesh K. Srivastava* (2025). Bacillus coagulans ameliorates inflammatory bone loss in post-menopausal osteoporosis via modulating the “Gut-ImmuneBone” axis, Gut Microbes, 17:1, 2492378, DOI: 10.1080/19490976.2025.2492378
Betsy Reshma Gilbert, Chirag Miglani, Arundhati Karmakar, Muneesh Pal, Vysakh C. Chandran, Sarika Gupta, Asish Pal, Munia Ganguli*,(2025) A combination of systemic mannitol and mannitol modified polyester nanoparticles for caveolae-mediated gene delivery to the brain, Molecular Therapy Nucleic Acids,Volume 36, Issue 1,2025,102480,ISSN 2162- 2531,https://doi.org/10.1016/j.omtn.2025.102480
Kajal Kamble, Ujjawal Kumar, Harsh Ahara, Mohit, Sumnil Bhola and Sarika Gupta* (2024) A novel ER stress regulator ARL6IP5 induces ER phagy to ameliorate the prion burden. Autophagy (2025) vol 21, n0. 3, 598- 619.
Ramakrishna Voggu, Durga DeviBalakrishnan, Priyanka Shukla, Venkat S wamy Puli, V. Surendra Babu Damerla, Sreekanth Rajan, Sridhar Chidara, Padma Mogili, Kalyan Kumar Pasunooti*, Sarika Gupta*. (2024) Discovery of tetrahydro γ-carboline based novel glucose uptake agent for the treatment of diabetes and Alzheimer’s diseases. Results in Chemistry, Volume 11, October 2024, 101778
Toshi S. Dhapodkar, Sarika Gupta, Bipin Kumar Gupta*. (2024) Lanthanide conjugated colour-tunable luminescent hydrogels as direct printable inks for anticounterfeiting and forensic applications. Materials Today Communications, Volume 40, 110200
Leena Sapra; Chaman Saini; Shivani Sharma; Dibyani Nanda; Aishwarya Nilakhe; Naibedya Chattopadhyay; Avtar Singh Meena; Pradyumna K Mishra; Sarika Gupta; Bhavuk Garg; Vikrant Manhas; Rupesh K Srivastava*.Targeting the osteoclastogenic cytokine IL-9 as a novel immunotherapeutic strategy in mitigating inflammatory bone loss in post menopausal osteoporosis. JBMR Plus, ziae120, https://doi.org/10.1093/jbmrpl/ziae120
Nisha Arora, Jagadish Hazra, Sandip Roy, Gaurav Bhati, Sarika Gupta, K Yogendran, Abhishek Chaudhuri, Amin Sagar and Sabyasachi Rakshit* (2024). Emergence of slip-ideal-slip behavior in tip-links serve as force filters of sound in hearing. Nature Communication, 15:1595.
Rai, Himanshu; Singh, Rishabh; Bharti, Prahalad; Kumar, Prabhat; Rai, Sanskriti; Varma, Tanmay Kumar; Chauhan, Brijesh Singh; Nilakhe, Aishwarya; Debnath, Joy; Dhingra, Renu; Mishra, Vijay; Gupta, Sarika; Krishnamurthy, Sairam; Yang, Jian; Garg, Prabha; Srikrishna, S.; Kumar, Saroj; Modi, Gyan. (2024) Rhodanine composite fluorescence probes to detect pathological hallmarks in Alzheimer's disease. Models Sensors and Actuators B: Chemical, 407, 135364.
Prabhat Upadhyay, Diya Kalra, Aishwarya S. Nilakhe, Vijay Agrawal, Sarika Gupta* (2023). Polyherbal Formulation PL02 Alleviates Pain, Inflammation, and Subchondral Bone Deterioration in an Osteoarthritis Rodent Model. Front. Nutr. Sec. Nutrition and Metabolism, Volume 10 – 2023. doi: 10.3389/fnut.2023.1217051
Pal S, G BR, Mohny FP, Choudhury SG, Karmakar A, Gupta S, Ganguli M*. (2023). Albumin Nanoparticles Surface Decorated with a Tumor Homing Peptide Help in Selective Killing of Triple-Negative Breast Cancer Cells. ACS Appl Mater Interfaces. doi: 10.1021/acsami.3c11561.
Upadhyay P, Tyagi A, Agrawal S, Kumar A, Gupta S*(2023). Bidirectional Effect of Triphala on Modulating Gut-Brain Axis to Improve Cognition in the Murine Model of Alzheimer's Disease. Mol Nutr Food Res. doi: 10.1002/mnfr.202300104.
Prabhat Upadhyay & Sarika Gupta* (2023). Dual mode of Triphala in the Reversal of cognition through Gut restoration in Antibiotic mediated prolonged Dysbiosis condition in 5XFAD mice. Experimental Neurology, vol 367
Parminder Singh, Kishore Gollapalli, Stefano Mangiola, Daniela Schranner, Mohd Aslam Yusuf, Manish Chamoli, StingL.Shi, Bruno Lopes Bastos, Tripti Nair, Annett Riermeier, Elena M. Vayndorf, JudyZ.Wu, Aishwarya Nilakhe, ……., Sarika Gupta, Vidya Velagapudi, Anthony T.
Papenfuss,Alaattin Kaya, Miguel Godinho Ferreir, Brian K. Kennedy, Julie K. Andersen,Gordon J. Lithgow, Abdullah Mahmood Ali, Arnab Mukhopadhyay, AarnoPalotie, Gabi Kastenmüller, Matt Kaeberlein, Henning Wackerhage, BhupinderPal, VijayK.Yadav* (2023). Taurine deficiency as a driver of aging. Science 380, eabn9257.
Ibrar Siddique, Kajal Kamble, Sakshi Gupta, Kavita Solanki, Sumnil Bhola, Nuzhat Ahsan, Sarika Gupta * (2023). ARL6IP5 ameliorated synuclein burden by inducing autophagy via preventing ubiquitination and degradation of ATG12. Int. J. Mol. Sci. 24(13), 10499.
Ramakrishna Voggu, Arundhati Karmakar, Venkat Swamy Puli, V. Surendra Babu Damerla, Padma Mogili, P. Amaladass, Sridhar Chidara *, Kalyan Kumar Pasunooti *, Sarika Gupta * (2023). Design, Synthesis, Molecular Docking Study and Biological Evaluation of Novel γ-Carboline Derivatives of Latrepirdine (Dimebon) as Potent Anticancer Agents. Molecules, 28(13), 4965;.
Mayuri Khandelwal, Kapil Manglani, Prabhat Upadhyay, Mohammad Azad, Sarika Gupta* (2022) AdipoRon induces AMPK activation and ameliorates Alzheimer’s like pathologies and associated cognitive impairment in APP/PS1 mice. Neurobiology of Disease 174, 105876
Himanshu Rai, Sarika Gupta, Saroj Kumar, Jian Yang, Sushil K. Singh, Chongzhao Ran, and Gyan Modi (2022) Near-Infrared Fluorescent Probes as Imaging and Theranostic Modalities for Amyloid-Beta and Tau Aggregates in Alzheimer’s Disease. J. Med. Chem. 65, 8550−8595
Girija Shankar Papanai, Krishna Rani Sahoo, Betsy Reshma G, Sarika Gupta, and Bipin Kumar Gupta (2022). Role of processing parameters in CVD grown crystalline monolayer MoSe2. RSC Adv., 12, 13428
Girija Shankar Papanai, Samanta Pal, Prabir Pal, Brajesh S. Yadav, Preeti Garg, Sarika Gupta, S. G. Ansari, and Bipin Kumar Gupta (2021). New insight into the growth of monolayer MoS2 flakes using an indigenously developed CVD setup: a study on shape evolution and spectroscopy. Mater. Chem. Front., 5, 5429-5441.
Pradeep Kumar, Sarika Gupta, Bipin Kumar Gupta (2021). A Facile Liquid Phase Exfoliation of Tungsten Diselenide using Dimethyl Sulfoxide as Polar Aprotic Solvent to Produce High‐quality Nanosheets. ChemNanoMat.
Ahmad F, Kumar R, Gupta S, Rathaur S (2020). Identification of a HSP14- 3-3 in Setariacervi and its cross-reactivity with W bancrofti-infected human sera. Parasite Immunol. Nov;42(11):e12777.
Mayuri Khandelwal, Kapil Manglani, Sarika Gupta, AshuBhanTiku (2020). Gamma radiation improves AD pathogenesis in APP/PS1 mouse model by potentiating insulin sensitivity. Heliyon, July; 6(7).
Neha Mittal, Garima Kedawat, Kanika, Sarika Gupta, and Bipin Kumar Gupta*(2020). An Innovative Method for Large-Scale Synthesis of Hexagonal Boron Nitride Nanosheets by Liquid Phase Exfoliation. Chemistry Select, 5, 12564– 12569.
Pal M, Khan J, Kumar R, Surolia A, Gupta S*(2019). Testosterone supplementation improves insulin responsiveness in HFD fed male T2DM mice and potentiates insulin signaling in the skeletal muscle and C2C12 myocyte cell line. PLoS One. Nov 6;14(11):e0224162.
Khan J, Salhotra S, Goswami P, Akhtar J, Jahan S, Gupta S, Sharma S, Banerjee BD, Parvez S, Gupta S*, Raisuddin S* (2019). Bisphenol A triggers axonal injury and myelin degeneration with concomitant neurobehavioral toxicity in C57BL/6J male mice. Toxicology, Dec 1;428:152299.
Manglani K, Vijayan V, Pathak C, Khandelwal M, Singh P, Chellappa S, Yadav VK, Surolia A, Gupta S*(2019). Development and characterization of supramolecular calcitonin assembly and assessment of its interactions with the bone remodelling process. Bone, Feb 21;122:123-135.
Khan J, Salhotra S, Ahmad S, Sharma S, Abdi SAH, Banerjee BD, Parvez S, Gupta S*, Raisuddin S*(2018). The protective effect of α-lipoic acid against bisphenol A-induced neurobehavioral toxicity. Neurochem Int. Sep;118:166-175.
Yadav S, Dwivedi VK, Gupta S, Surolia A(2018). Benzothiophenes as Potent Analgesics Against Neuropathic Pain. Adv Exp Med Biol. 2018;1112:245-254.
Ahsan N, Siddique IA, Gupta S*, Surolia A*(2018). A routinely used protein staining dye acts as an inhibitor of wild type and mutant alpha synuclein aggregation and modulator of neurotoxicity. Eur J Med Chem. Jan 1;143:1174-1184.
Bipin Kumar Gupta, Pawan Kumar,Garima Kedawat, Kanika, Sajna Antony Vithayathil, Amit Kumar Gangwar, Satbir Singh, Pradeep Kumar Kashyap, RimliLahon,V. N. Singh, Abhay D. Deshmukh, Tharangattu N. Narayanan, Nidhi Singh, Sarika Gupta and Benny Abraham Kaipparettu. Tunable luminescence from two-dimensional BCNO nanophosphor for high-contrast cellular imaging. RSC Adv., 2017, 7, 41486
Viji Vijayan, Sakshi Gupta Sarika Gupta* (2017). Bone morphogenetic protein-5, a key molecule that mediates differentiation in MC3T3E1 osteoblast cell line. Biofactors, May 12. doi: 10.1002/biof.1360.
Viji Vijayan and Sarika Gupta* (2017). Role of Osteocytes in Mediating Bone Mineralization during Hyperhomocysteinemia. Journal of Endocrinology, Jun;233(3):243-255.
Chattopadhyay T., Ranjan R., Gupta S*, Surolia A* (2017). Bone morphogenetic protein-7 (BMP-7) augments insulin sensitivity in mice with type II diabetes mellitus by potentiating PI3K/AKT pathway. Biofactors, Mar;43(2):195-209.
Pal M, Gupta S* (2017). Testosterone supplementation improves glucose homeostasis despite increasing hepatic insulin resistance in male mouse model of type 2 diabetes mellitus. Nutrition & Diabetes, Dec 12;6(12):e236.
Srivastava A, Sharma S, Sadanandan S, Gupta S, Singh J, Gupta S, Haridas V, Kundu B. (2017). Modulation of prion polymerization and toxicity by rationally designed peptidomimetics. Biochem J. Jan 1;474(1):123-147.
Gupta BK, Singh S, Kumar P, Lee Y, Kedawat G, Narayanan TN, Vithayathil SA, Ge L, Zhan X, Gupta S, Martí AA, Vajtai R, Ajayan PM, Kaipparettu BA (2016). Bifunctional Luminomagnetic Rare-Earth Nanorods for High-Contrast Bioimaging Nanoprobes. Sci Rep.Sep2;6:32401.
Rawat P, Ahmad I, Thomas SC, Pandey S, Vohora D, Gupta S, Ahmad FJ, Talegaonkar S (2016). Revisiting bone targeting potential of novel
hydroxyapatite based surface modified PLGA nanoparticles of risedronate: Pharmacokinetic and biochemical assessment. Int J Pharm. Jun 15;506(1- 2):253-61.
Ahsan N, Mishra S, Jain MK, Surolia A, Gupta S* (2015). Curcumin Pyrazole and its derivative (N-(3-Nitrophenylpyrazole) Curcumin inhibits aggregation, disrupt fibrils and modulate toxicity of Wild type and Mutant α-Synuclein. Sci Rep. May 18;5:9862.
Pasi S, Kant R, Gupta S, Surolia A (2015). Novel multimeric IL-1 receptor antagonist for the treatment of rheumatoid arthritis. Biomaterials. Feb;42:121-33.
Rawat P, Manglani K, Gupta S, Kalam A, Vohora D, Ahmad FJ, Talegaonkar S(2015). Design and Development of Bioceramic Based Functionalized PLGA Nanoparticles of Risedronate for Bone Targeting: In vitro Characterization and Pharmacodynamic Evaluation. Pharm Res. Oct;32(10):3149-58.
Pathak C, Ranjan Singh R, Yadav S, Kapoor N, Raina V, Gupta S*, Surolia A* (2014). Design, synthesis and biological evaluation of benzothiophene carboxamide derivatives as analgesics and anti-inflammatory agents. IUBMB Life, Mar 26.
Vijayan V, Khandelwal M, Manglani K, Gupta S*, Surolia A* (2014). Methionine down-regulates TLR4/MyD88/NF-κB signalling in osteoclast precursors to reduce bone loss during osteoporosis. Br J Pharmacol. Jan;171(1):107-21.
Raina V, Gupta S*, Yadav S, Surolia A* (2013). Simvastatin induced neurite outgrowth unveils role of cell surface cholesterol and acetyl CoA carboxylase in SH-SY5Y cells. PLoS One. 2013 Sep 11;8(9):e74547.
Vijayan V, Khandelwal M, Manglani K, Singh RR, Gupta S*, Surolia A* (2013). Homocysteine alters the osteoprotegerin/RANKL system in the osteoblast to promote bone loss: pivotal role of the redox regulator forkhead O1. Free Radic Biol Med. Mar 15;61C:72-84. (IF 7.4)
Tomar D, Khan T, Singh RR, Mishra S, Gupta S, Surolia A, Salunke D M (2012). Crystallographic study of novel transthyretin ligands exhibiting negative-cooperativity between two T4 binding sites. Plos One;7(9):e43522.
Banerjee T, Singh RR, Gupta S, Surolia A, Surolia N (2012). 15- Deoxyspergualin hinders physical interaction between basic residues of transit peptide in PfENR and Hsp70-1.IUBMB Life. Jan;64(1):99-107.
Tripathi R, Samadder T, Gupta S, Surolia A*, Shaha C* (2011). Anticancer activity of a combination of cisplatin and fisetin in embryonal carcinoma cells and xenograft tumors. Mol Cancer Ther. Feb; 10(2):255-68.
Gupta S, Chattopadhyay T, Pal Singh M, Surolia A* (2010). Supramolecular insulin assembly II for a sustained treatment of type 1 diabetes mellitus. Proc Natl Acad Sci U S A. Jul 27;107(30):13246-51.
Gupta S*, Babu P, Surolia A*(2010). Biphenyl ethers conjugated CdSe/ZnS core/shell quantum dots and interpretation of the mechanism of amyloid fibril disruption. Biomaterials. Sep;31(26):6809-22.
Chopra T, Banerjee S, Gupta S, Yadav G, Anand S, Surolia A, Roy RP, Mohanty D, Gokhale RS* (2008). Novel Intermolecular Iterative Mechanism for Biosynthesis of Mycoketide Catalyzed by a Bimodular
Polyketide Synthase. PLoS Biology. 6(7):e163. Sarika Gupta, Manmohan Chhibber, Sharmistha Sinha, Avadhesha Surolia, (2007). Design of Mechanism-Based Inhibitors of Transthyretin Amyloidosis: Studies with Biphenyl Ethers and Novel Structural Templates. Journal of Medicinal Chemistry.50(23):5589-99.
54. Sarika Gupta, Rahul Modak, Namita Surolia, Avadhesha Surolia. Partial molar volumes of acyl carrier proteins are related to their states of acylation. Biochem and Biophys Res Comm, 380, 4, 20, 763-768.
Rathaur S, Yadav M, Gupta S, Anandharaman V, Reddy MV (2008). Filarial glutathione-S-transferase: A potential vaccine candidate against lymphatic filariasis. Vaccine. 26(32):4094-100. Gupta S, Singh A, Yadav M, Singh K, Rathaur S (2007). MALDI mass sequencing and characterization of filarial glutathione-S-transferase. Biochem and Biophys Res Com. 4; 356(2):381-385.
Sarika Gupta, Y. P. Bhandari, M.V.R. Reddy, B. C. Harinath, S. Rathaur (2005). Setaria cervi Glutathione-S-transferase: Immunoprophylactic potential against filarial parasite Brugia malayi. Exp. Parasitol, 109 (4), 252-255.
Sarika gupta, Sushma Rathaur (2005). Filarial Glutathione-S-transferase: Its Induction by Xenobiotics and Potential as Drug Target. Acta Biochemica Polonica, 52(2), 493-500.
Y. Srivastava, Sarika Gupta, DayaramPokharelandSushmaRathaur. Setaria cervi collagenase: IgG Cleavage and inhibition by W. bancrofti infected sera. Acta Parasitologica, 49(3), 253-259.
(*corresponding author)
List of any books/chapters: 1.
How Homocysteine Modulates the Function of Osteoblasts and Osteocytes. Sarika Gupta and Viji Vijayan. “Non Proteinogenic Amino Acids” 978-1-78984-729-1 Intech Open.
Prabhat Upadhyay, Diya Kalra, Sarika Gupta, and Sunil Kumar Mishra (2022) Reversal of Metabolic Disorder Through the Restoration of Gut Microbiota. Nutritional Neuroscience (springer).
Abhimanyu Thakur, Dipanjan Ghosh, Rajesh Sarkar, Sera Averbek, Ashok Iyaswamy, Anoop Kumar, Prabhat Upadhyay, Sarika Gupta, Vikas Kumar, Amrenrda Ajay. The Neuroinflammation Enigma: Cracking the Code of the Gut-Brain Connection. CRC-Press, Taylor and Fransis group.