Many textbooks state that phenotype is determined by the interaction between genotype and environment. However, most studies using model animals are conducted under conditions of constant temperature and day/night length, and few model animals can reproducibly study the genotype-phenotype relationship in relation to environmental changes. Medaka, a small temperate fish, can live in water temperatures ranging from 4°C in winter to 40°C in summer. They can also survive in both seawater and freshwater. Medaka are attracting attention as a model that can reproducibly analyze various life phenomena in such fluctuating environments. In this workshop, we will discuss medaka as new models for studies of gene-environment interactions, phenotypic variation among different environments or populations, and also discuss other topics.
This workshop is open to the public and in-person only, and we ask that you register in order to estimate the number of participants. Officially language is English.
Date: 26th -27th April 2024
Venue: National Institute for Basic Biology (See map below):
Conference Room (1F, Room 111-112)
Reception: April 26, 12:30 - 13:15 p.m.
26th April 2024
13:20-13:30
Kiyoshi Naruse (National Institute for Basic Biology)
Opening remarks: MIKK Panel, Wild medaka derived strains and more
Why do we go to fishing in wild?
13:30-14:00
Bettina Welz (COS Heidelberg)
Discovery and functional validation of Gene x Environment interaction effects on medaka heart rate in response to temperature changes.
14:00-14:30
Risa Suzuki (COS Heidelberg)
Determination of the genetic contributors to visual traits & retina degeneration using a highly inbred population panel.
14:30-15:00
Satoshi Ansai (Ushimado Marine Institute, Okayama University)
Genomics in wild-derived strains of medaka and its relatives.
15:00-15:10
Coffee Break
15:10-15:40
Rie Hara and Masato Kinoshita (Graduate School of Agriculture, Kyoto University)
Factors contributing to variation in vertebral numbers among local populations of medaka.
15:40-16:10
Ryutaro Ueda, Satoshi Ansai and Hideaki Takeuchi (Graduate School of Life Sciences, Tohoku University)
Rapid body coloration changes in Oryzias celebensis as a social signal influenced by environmental background.
16:10-16:40
Philip Watson (COS Heidelberg)
Gene-environment interactions in medaka – identification of genes that mediate pollutant responses.
16:40-17:10
Jochen Wittbrodt, (COS Heidelberg)
Medaka and the genetics of individuality.
17:40~ Seminar Room 1 (1F, Room132-134)
The social gathering party and discussion with foods and drinks.
27th April 2024
9:00-9:30
Fanny Defranoux (EMBL-EBI Hinxton/Cambridge)
The use of the Medaka Inbred Kiyosu-Karlsruhe panel to study GxE interactions after xenobiotic exposure.
9:30-10:00
Eitaro Sawayama (Department of Marine Science, Nihon University)
A classical but new phenotypic plasticity of medaka: salinity acclimation.
10:00-10:30
Yusuke Takehana (Nagahama Institute of Bio-Science and Technology)
Diverse sex chromosomes and sex-determining genes in the medaka fishes.
10:30-10:40
Coffee Breaks
10:40-11:10
Ryu Tsukasa and Yukiko Ogino (Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University)
Regulatory mechanisms of androgen mediated sex characteristics in teleost fishes.
11:10-11:40
Thomas Thumberger (COS Heidelberg)
Human disease models by advanced genome editing.
Lunch time 11:40-12:30
12:30-13:30
Jochen Gehrig (Bruker ACQUIFER)
ACQUIFER IM - Automated Microscopy and Whole Organism Screening. (include Hands on seminar)
13:30-14:00
Saul Pierotti (EMBL-EBI Hinxton/Cambridge)
Extensive Gene x Environment interactions in the outbred vertebrate genetics of a standard physiological phenotype.
14:00-14:30
Takashi Yoshimura (Nagoya University)
Medaka as a model to understand the seasonal timer and winter depression.
14:30-14:50
Coffee Breaks
14:50-15:20
Tomoya Nakayama (Nagoya University)
Transcriptome analysis of adaptation to seasonal temperature changes.
-Toward understanding the adaptation mechanisms of medaka to a wide range of temperatures-
15:20-15:50
Tokiho Akiyama and Takafumi Katsumura (Laboratory of Anatomy, Kitasato University School of Medicine)
Medaka Anthropology: Understanding Human Variation in Natural Environments through Local Medaka Populations and Their Evolutionary History.
15:50-
Open discussion among presenters and audiences.
Map of National institute for Basic Biology (Myodaiji ) 基礎生物学研究所(明大寺地区)