Program

 

Day 1

March 22 (Wed)

Registration 12:00 ～ 13:00

13:00～ 13:10

Opening Remarks

Jared Toettcher (Princeton U.) and Hideaki Takayanagi/Naoto Ueno (NINS, IRCC-QIB)

13:10 ～ 14:40

Session 1

Subcellular organization

Chairs: Jared Toettcher and Naoto Ueno

13:10 ～ 13:40

Complex Fluids: Nuclear Condensates in Physiology and Disease

Cliff Brangwynne

13:40 ～ 14:10

Intra- and inter-cellular communication during viral infection

Ileana Cristea

14:10 ～ 14:25

Dynamics of phase-separated ZO-1 condensates and their effects on cell migration 

Sayuki Hirano (from poster #1)

14:25 ～ 14:40

Harnessing optogenetics to modulate and understand biomolecular condensates

Ellen Brumbaugh-Reed (From poster #6)

14:40 ～ 15:40

COFFEE BREAK

at the atrium of Maeder Hall

15:40 ～ 17:40 

Session 2

Mechanobiology

Chair: Naoto Ueno

15:40 ～ 16:10

Nutritional control of thyroid morphogenesis

Asako Shindo

16:10 ～ 16:40

The mechanics of tube folding

Celeste Nelson

16:40 ～ 17:10

Did the tape run twice? Morphogenesis of amoebozoa Dictyostelium - cell polarity, cell migration and cell rearrangement

Satoshi Sawai

17:10 ～ 17:25

Inference of effective mechanical potential of cell-cell interactions during embryogenesis

Hiroshi Koyama (from poster #2)

17:25 ～ 17:40

Special Presentation for Young Investigators:

NIH Funding Opportunities for Trainees and New Investigators

Reiko Toyama

17:40 ～ 19:30

Poster Presentations

At the atrium of Maeder Hall, Light meal served
(speakers and poster presenters only)

#1

Sayuki Hirano (NIBB, Japan )  Dynamics of phase-separated ZO-1 condensates and their effects on cell migration

#2

Hiroshi Koyama (NIBB, Japan )  Inference of effective mechanical potential of cell-cell interactions during embryogenesis

#3

Yusuke Mii (ExCELLS/NIBB, Japan )  Mutual regulations between Wnt and core PCP components establish planar cell polarity

#4

Toshikazu Miyata (NIPS, Japan )  Structural covariance and heritability of the white matter tract and cortical area in the visual system of living humans

#5

 Dawei Liu (Mol. Bio., Princeton U.) IFI16 phase separation via multi-phosphorylation drives innate immune signaling

#6

Ellen Brumbaugh Reed  (Moi. Bio., Princeton U. )  Harnessing optogenetics to modulate and understand biomolecular condensates

#7

Sarah Gernhart  (Chem., Princeton U. )  Complex System Chemical Dynamics

#8

Tomohito Minakuchi (PNI, Princeton U. )  Independent inhibitory control mechanisms for aggressive motivation and action

#9

Nicholas Treen (LSI, Princeton U. )  An FGF Timer for Zygotic Genome Activation

#10

Hengyuan Liu (Dept. Chem., Princeton U.) Exploring the Impact of Symmetry in Chromatin Remodeling

#11

Elena Cho (Dept. Mol. Biol., Princeton U.) E-cadherin Substrate as a Bioinspired Material to Modulate the Collective Behavior of Tissue

#12

Jerelle Joseph (Dept. Chem. Bio. Eng., Princeton U.) Coarse‑grained model for protein phase separation with quantitative accuracy

#13

Rosie Graham (IMS, JAPAN)  The role of binding modules in enzymatic poly(ethylene terephthalate) hydrolysis at high-solids loading

#14

Steven Bodine (Dept. Mol. Bio., Princeton U.)  Biochemical reconstitution of the S. aureus agr quorum sensing pathway reveals key insights into pheromone biosynthesis

#15

Alana Bernys (Dept. Mol. Bio. Princeton U.)  Imaging Cell Cycle-Mediated Embryonic Size Control in Mammals

#16

Laurence Lemaire (Dept. Mol. Bio., Princeton U.)  Cereblon controls the timing of muscle differentiation in Ciona

Day 2

March 23 (Thu)

9:00～ 10:30

Session 3

Developmental gene regulation

Chairs: Michael Levine and Yasuko Akiyama-Oda


9:00～ 9:30

Long-range connectivity of the regulatory genome

Michael Levine

9:30～ 10:00

Reconstruction of segmented body pattern in single-nuc analysis of spider embryos

Yasuko Akiyama-Oda

10:00～ 10:30

Dynamics of transcription hubs in the Drosophila embryo

Takashi Fukaya

10:30 ～ 10:50

COFFEE BREAK

at the atrium of Maeder Hall

10:50～ 12:05

Session 4

Single-molecule biophysics

Chairs: Haw Yang and Ryota Iino

10:50～ 11:20

Complex system chemical dynamics

Haw Yang

11:20～ 11:50

Engineering rotary and linear molecular motor proteins

Ryota Iino

11:50～ 12:05

Time-resolved 3D multi-resolution imaging: Design, construction, and applications

Tian Zao

12:05 ～ 13:00

Lunch

at the atrium of Maeder Hall

13:00～ 14:45

Session 5

Cell signaling

Chairs: Denelle Devenport and Kazuhiro Aoki

13:00～ 13:30

Multiscale coordination of planar cell polarity

Danelle Devenport

13:30～ 14:00

Quantitative analysis of cell cycle by live-cell imaging and optogenetics

Kazuhiro Aoki

14:00～ 14:30

Towards light-guided embryogenesis: optogenetics and biosensors to probe developmental patterning

Jared Toettcher

14:30～ 14:45

Mutual regulations between Wnt and core PCP components establish planar cell polarity

Yusuke Mii (from poster #3)

14:45 ～ 15:20

COFFEE BREAK

at the atrium of Maeder Hall

15:20～ 16:35

Session 6

Neurobiology

Chairs: Fenna Krienen and Nobuyuki Shiina

15:20～ 15:50

Single cell sequencing to reveal influences of evolutionary and developmental lineage on primate brain cell types

Fenna Krienen

15:50～ 16:20

ILF3 prion-like domain regulates gene expression and fear memory under chronic stress

Nobuyuki Shiina

16:20～ 16:35

Independent inhibitory control mechanisms for aggressive motivation and action

Tomohito Minakuchi (from poster #8)

16:35～ 16:50

Closing Remarks

Michael Levine (LSI, Princeton U.)