Next invited talk:

Michel Steinmetz

PSI Center for Life Sciences, Paul Scherrer Institute, Villigen, Switzerland

Microtubule-controlled signal transduction and interactions with anticancer drugss

Microtubules are critical components of the cytoskeleton composed of tubulin. They play essential roles in cellular processes such as division, motility, intracellular transport, and signaling. These functions make microtubules and their associated proteins highly attractive targets for drug development to address diseases like cancer, neurological disorders, and infections. In my talk, I will share our efforts to unravel the mechanisms of action of microtubule-targeting agents and describe approaches to enable their rational design. Additionally, I will highlight our recent work on microtubule-controlled signaling mechanisms - an underexplored yet pivotal aspect of microtubule biology that offers promising opportunities for advancing our understanding of cellular signaling pathways.