Lab Overview
Our lab focuses on understanding the molecular basis for sex differences in human physiology and pathology. Many autoimmune diseases feature increased prevalence in females (~78% female overall and up to ~ 95% female for specific diseases). In contrast, infectious diseases and cancer affect more men than women. The molecular mechanisms underlying these observed sex differences are unclear, and to fill this knowledge gap we seek to define immune- and cancer-associated pathways that are differentially regulated between the two sexes using a combination of molecular, cellular and animal-based approaches. We hope our research will shed light on the biological significance of sexual dimorphism, and provide novel ways to combat autoimmunity, infections and cancer.
First Lab Meeting of Fall 2024 semester: 11/7
Welcome our new undergraduate researchers, Alekya and Kaylee!
Welcome our new research assistant, Aubree!