Information storage in synthetic DNA based on nanopore sequencing offers fast, portable, and cost-effective technology that may help bring about the next revolution in the ICT industry: archival storage in synthetic DNA. Following the success of Shannon’s approach in the development of wireless communications we can develop a comprehensive theoretical foundation that encompasses channel models, noise characteristics, and inherent limitations of nanopore-based DNA storage.
The DNA Squiggleism group @ Monash University (Australia) combines deep learning techniques with information theory, communications theory, and signal processing methods to efficiently encode information in synthetic DNA and reliably extract it from the DNA squiggles produced by nanopore sequencing.