publications

Publications:

• Brestoff JR, Singh KK, Aquilano K, Becker LB, Berridge MV, Boilard E, Caicedo A, Crewe C, Enríquez JA, Gao J, Gustafsson ÅB, Hayakawa K, Khoury M, Lee YS, Lettieri-Barbato D, Luz-Crawford P, McBride HM, McCully JD, Nakai R, Neuzil J, Picard M, Rabchevsky AG, Rodriguez AM, Sengupta S, Sercel AJ, Suda T, Teitell MA, Thierry AR, Tian R, Walker M, Zheng M. Recommendations for mitochondria transfer and transplantation nomenclature and characterization. Nat Metab. 2025 Jan;7(1):53-67. DOI: 10.1038/s42255-024-01200-x PMID: 39820558.

• Doulamis IP, Tzani A, Alemany VS, Nomoto RS, Celik A, Recco DP, Saeed MY, Guariento A, Plutzky J, Emani SM, Del Nido PJ, McCully JD. Mitochondrial transplantation normalizes transcriptomic and proteomic shift associated with ischemia reperfusion injury in neonatal hearts donated after circulatory death. Sci Rep. 2024 Dec 28;14(1):31236. DOI: 10.1038/s41598-024-82578-2. PMID: 39732955

• Bechet NB, Celik A, Mittendorfer M, Wang Q, Huzevka T, Kjellberg G, Boden E, Hirdman G, Pierre L, Niroomand A, Olm F, McCully JD, Lindstedt S. Xenotransplantation of mitochondria: A novel strategy to alleviate ischemia-reperfusion injury during ex vivo lung perfusion. J Heart Lung Transplant. 2024 Nov 12:S1053-2498(24)01938-7. DOI: 10.1016/j.healun.2024.10.033. PMID: 39536924.

• Bechet NB, Celik A, Wang Q, Huzevka T, Middendorf M, Niroomand A, Boden E, Hirdman G, . Kjellberg G, Pierre L, Olm F, McCully JD, Lindstedt S. Mitochondrial xenotransplantation during ex vivo lung perfusion: leveraging rodents as a fresh organelle source to tackle ischemia reperfusion injury. J Heart Lung Transpl.  43: S140-S141, 2024 

• Arroum T, Hish GA, Burghardt KJ, Ghaloush M, Bazzi B, Mrech A, Morse PT, Britton SL, Koch LG, McCully JD, Hüttemann M, Malek MH. Mitochondria transplantation: rescuing innate muscle bioenergetic impairment in a model of aging and exercise intolerance. J Strength Cond Res. 2024 Jul 1;38(7):1189-1199. DOI: 10.1519/JSC.0000000000004793. PMID: 38900170

• Bodenstein DF, Siebiger G, Zhao Y, Clasky AJ, Mukkala AN, Beroncal EL, Banh L, Aslostovar L, Brijbassi S, Hogan SE, McCully JD, Mehrabian M, Petersen TH, Robinson LA, Walker M, Zachos C; MITO2i-MbD Mitochondrial Transplant Consortium; Viswanathan S, Gu FX, Rotstein OD, Cypel M, Radisic M, Andreazza AC. Bridging the gap between in vitro and in vivo models: a way forward to clinical translation of mitochondrial transplantation in acute disease states. Stem Cell Res Ther. 2024 May 31;15(1):157. DOI: 10.1186/s13287-024-03771-8. PMID: 38816774  

• Arroum T, Hish GA, Burghardt KG, McCully JD, Hüttemann M, Malek MH. Mitochondrial transplantation's role in rodent skeletal muscle bioenergetics: recharging the engine of aging. Biomolecules. 2024 Apr 18;14(4):493. DOI: 10.3390/biom14040493 

• Alemany VS, Nomoto R, Saeed MY, Celik A, Regan WL, Matte GS, Recco DP, Emani SM, del Nido PJ, McCully JD. Mitochondrial transplantation preserves myocardial function and viability in pediatric and neonatal pig hearts donated after circulatory death. J Thorac Cardiovasc Surg. 2023 May 20:S0022-5223(23)00434-8.DOI: 10.1016/j.jtcvs.2023.05.010 

• Alemany VS, Recco DP, Emani SM, del Nido PJ, McCully JD. Model of Ischemia and Reperfusion Injury in Rabbits. PMID: 37982519 , DOI: 10.3791/64752

• Celik A, Orfany A, Dearling J, Del Nido PJ, McCully JD, Bakar-Ates F. Mitochondrial transplantation: Effects on chemotherapy in prostate and ovarian cancer cells in vitro and in vivo. Biomed Pharmacother. 2023 May;161:114524. doi: 10.1016/j.biopha.2023.114524  Epub 2023 Mar 20. PMID: 36948134

• Rossi A, Asthana A, Riganti C, Sedrakyan S, Byers LN, Robertson J, Senger RS, Montali F, Grange C, Dalmasso A, Porporato PE, Palles C, Thornton ME, Da Sacco S, Perin L, Ahn B, McCully J, Orlando G, Bussolati B. Mitochondria Transplantation Mitigates Damage in an In Vitro Model of Renal Tubular Injury and in an Ex Vivo Model of DCD Renal Transplantation. Ann Surg. 2023 Dec 1;278(6):e1313-e1326. doi: 10.1097/SLA.0000000000006005. Epub 2023 Jul 14. PMID: 37450698, ·  PMCID: PMC10631499 

• McCully JD, del Nido PJ Emani. Therapeutic Mitochondrial Transplantation. Current Opinion in Physiology. https://doi.org/10.1016/j.cophys.2022.100558.

• Doulamis IP, Nomoto RS, Tzani A, Hong X, Duignan T, Celik A, del Nido PJ, McCully JD. Transcriptomic and Proteomic Pathways of Diabetic and Non-diabetic Mitochondrial Transplantation. Nature Sci Rep. 2022;12:22101. doi: 10.1038/s41598-022-25858-z. PMID: 36543810, PMCID: PMC9772345. 

• Wyant GA, Yu W, Doulamis IP, Nomoto RS, Saeed MY, Duignan T, McCully JD, Kaelin WG Jr. Mitochondrial remodeling and ischemic protection by G protein-coupled receptor 35 agonists. Science. 2022 Aug 5;377(6606):621-629. doi: 10.1126/science.abm1638. Epub 2022 Aug 4. PMID: 35926043

• McCully JD, Del Nido PJ, Emani SM. Mitochondrial transplantation for organ rescue. Mitochondrion. 2022 Feb 22;64:27-33. doi: 10.1016/j.mito.2022.02.007. PMID: 35217248. 

• Doulamis IP, McCully JD. Mitochondrial Transplantation for Ischemia Reperfusion Injury. Methods Mol Biol. 2021;2277:15-37. PMID: 34080142. 

• Doulamis IP, Guariento A, Saeed MY, Nomoto RS, Duignan T, Del Nido PJ, McCully JD. A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion. J Vis Exp. 2021 Feb 2;(168). doi: 10.3791/62230. PMID: 33616119.

• Guariento A, Piekarski BL, Doulamis IP, Blitzer D, Ferraro AM, Harrild DM, Zurakowski D, Del Nido PJ, McCully JD, Emani SM. Autologous mitochondrial transplantation for cardiogenic shock in pediatric patients following ischemia-reperfusion injury. J Thorac Cardiovasc Surg. 2020 Dec 01. PMID: 33349443.

• Duignan T, Guariento A, Doulamis IP, Kido T, Regan WL, Saeed M, Hoganson DM, Emani SM, Del Nido PJ, McCully JD, Matte GS. A Multi-Mode System for Myocardial Functional and Physiological Assessment during Ex Situ Heart Perfusion. J Extra Corpor Technol. 2020 Dec; 52(4):303-313. PMID: 33343033.

• McCully JD, Doulamis IP. Commentary: Independent, additive or linked: A novel therapeutic option for the treatment of pulmonary hypertension may involve more than one mechanism. J Thorac Cardiovasc Surg. 2020 Aug 20. PMID: 32919766.

• Weixler V, Lapusca R, Grangl G, Guariento A, Saeed MY, Cowan DB, Del Nido PJ, McCully JD, Friehs I. Autogenous mitochondria transplantation for treatment of right heart failure. J Thorac Cardiovasc Surg. 2020 Aug 10. PMID: 32919774.

• Doulamis IP, Guariento A, Duignan T, Kido T, Orfany A, Saeed MY, Weixler VH, Blitzer D, Shin B, Snay ER, Inkster JA, Packard AB, Zurakowski D, Rousselle T, Bajwa A, Parikh SM, Stillman IE, Del Nido PJ, McCully JD. Mitochondrial transplantation by intra-arterial injection for acute kidney injury. Am J Physiol Renal Physiol. 2020 09 01; 319(3):F403-F413. PMID: 32686525.

• Guariento A, Doulamis IP, Duignan T, Kido T, Regan WL, Saeed MY, Hoganson DM, Emani SM, Fynn-Thompson F, Matte GS, Del Nido PJ, McCully JD. Mitochondrial transplantation for myocardial protection in ex-situ perfused hearts donated after circulatory death. J Heart Lung Transplant. 2020 Jun 29. PMID: 32703639.

• Doulamis IP, Guariento A, Duignan T, Orfany A, Kido T, Zurakowski D, Del Nido PJ, McCully JD. Mitochondrial transplantation for myocardial protection in diabetic hearts. Eur J Cardiothorac Surg. 2020 05 01; 57(5):836-845. PMID: 31782771.

• McCully JD, Emani SM, Del Nido PJ. Letter by McCully et al Regarding Article, "Mitochondria Do Not Survive Calcium Overload". Circ Res. 2020 04 10; 126(8):e56-e57. PMID: 32271682.

• Guariento A, Doulamis IP, Duignan T, Kido T, Regan WL, Saeed M, Hoganson DM, Emani SM, Matte GS, Del Nido PJ, McCully JD. Mitochondrial Transplantation for Myocardial Protection in Ex-Situ Perfused Hearts Donated after Cardio-Circulatory Death. J Heart Lung Transplant. 2020 Apr; 39(4S):S87. PMID: 32466053.

• McCully JD, Emani SM, Del Nido PJ. Reply: Intracoronary Delivery of Mitochondria to Prevent Ischemia-Reperfusion Injury: Challenging Pathway From Bench to Bedside. JACC Basic Transl Sci. 2020 Feb; 5(2):209. PMID: 32140627.

• Shin B, Saeed MY, Esch JJ, Guariento A, Blitzer D, Moskowitzova K, Ramirez-Barbieri G, Orfany A, Thedsanamoorthy JK, Cowan DB, Inkster JA, Snay ER, Staffa SJ, Packard AB, Zurakowski D, Del Nido PJ, McCully JD. A Novel Biological Strategy for Myocardial Protection by Intracoronary Delivery of Mitochondria: Safety and Efficacy. JACC Basic Transl Sci. 2019 Dec; 4(8):871-888. PMID: 31909298.    

• Moskowitzova K, Orfany A, Liu K, Ramirez-Barbieri G, Thedsanamoorthy JK, Yao R, Guariento A, Doulamis IP, Blitzer D, Shin B, Snay ER, Inkster JAH, Iken K, Packard AB, Cowan DB, Visner GA, Del Nido PJ, McCully JD. Mitochondrial transplantation enhances murine lung viability and recovery after ischemia-reperfusion injury. Am J Physiol Lung Cell Mol Physiol. 2020 01 01; 318(1):L78-L88. PMID: 31693391.

• Guariento A, Blitzer D, Doulamis I, Shin B, Moskowitzova K, Orfany A, Ramirez-Barbieri G, Staffa SJ, Zurakowski D, Del Nido PJ, McCully JD. Preischemic autologous mitochondrial transplantation by intracoronary injection for myocardial protection. J Thorac Cardiovasc Surg. 2020 Aug; 160(2):e15-e29. PMID: 31564546.

• Blitzer D, Guariento A, Doulamis IP, Shin B, Moskowitzova K, Barbieri GR, Orfany A, Del Nido PJ, McCully JD. Delayed Transplantation of Autologous Mitochondria for Cardioprotection in a Porcine Model. Ann Thorac Surg. 2020 03; 109(3):711-719. PMID: 31421103.

• Orfany A, Arriola CG, Doulamis IP, Guariento A, Ramirez-Barbieri G, Moskowitzova K, Shin B, Blitzer D, Rogers C, Del Nido PJ, McCully JD. Mitochondrial transplantation ameliorates acute limb ischemia. J Vasc Surg. 2020 03; 71(3):1014-1026. PMID: 31353269.

• Moskowitzova K, Shin B, Liu K, Ramirez-Barbieri G, Guariento A, Blitzer D, Thedsanamoorthy JK, Yao R, Snay ER, Inkster JAH, Orfany A, Zurakowski D, Cowan DB, Packard AB, Visner GA, Del Nido PJ, McCully JD. Mitochondrial transplantation prolongs cold ischemia time in murine heart transplantation. J Heart Lung Transplant. 2019 01; 38(1):92-99. PMID: 30391192.

• Emani SM, McCully JD. Mitochondrial transplantation: applications for pediatric patients with congenital heart disease. Transl Pediatr. 2018 Apr; 7(2):169-175. PMID: 29770298.

• Ramirez-Barbieri G, Moskowitzova K, Shin B, Blitzer D, Orfany A, Guariento A, Iken K, Friehs I, Zurakowski D, Del Nido PJ, McCully JD. Alloreactivity and allorecognition of syngeneic and allogeneic mitochondria. Mitochondrion. 2019 05; 46:103-115. PMID: 29588218.

• Cowan DB, Yao R, Thedsanamoorthy JK, Zurakowski D, Del Nido PJ, McCully JD. Transit and integration of extracellular mitochondria in human heart cells. Sci Rep. 2017 12 12; 7(1):17450. PMID: 29234096.

• McCully JD. Invited Commentary. Ann Thorac Surg. 2017 10; 104(4):1304-1305. PMID: 28935303.

• McCully JD, Cowan DB, Emani SM, Del Nido PJ. Mitochondrial transplantation: From animal models to clinical use in humans. Mitochondrion. 2017 05; 34:127-134. PMID: 28342934.

• Emani SM, Piekarski BL, Harrild D, Del Nido PJ, McCully JD. Autologous mitochondrial transplantation for dysfunction after ischemia-reperfusion injury. J Thorac Cardiovasc Surg. 2017 07; 154(1):286-289. PMID: 28283239.

• Shin B, Cowan DB, Emani SM, Del Nido PJ, McCully JD. Mitochondrial Transplantation in Myocardial Ischemia and Reperfusion Injury. Adv Exp Med Biol. 2017; 982:595-619. PMID: 28551809.

• Kaza AK, Wamala I, Friehs I, Kuebler JD, Rathod RH, Berra I, Ericsson M, Yao R, Thedsanamoorthy JK, Zurakowski D, Levitsky S, Del Nido PJ, Cowan DB, McCully JD. Myocardial rescue with autologous mitochondrial transplantation in a porcine model of ischemia/reperfusion. J Thorac Cardiovasc Surg. 2017 04; 153(4):934-943. PMID: 27938904.

• Cowan DB, Yao R, Akurathi V, Snay ER, Thedsanamoorthy JK, Zurakowski D, Ericsson M, Friehs I, Wu Y, Levitsky S, Del Nido PJ, Packard AB, McCully JD. Intracoronary Delivery of Mitochondria to the Ischemic Heart for Cardioprotection. PLoS One. 2016; 11(8):e0160889. PMID: 27500955.

• McCully JD, Levitsky S, Del Nido PJ, Cowan DB. Mitochondrial transplantation for therapeutic use. Clin Transl Med. 2016 Mar; 5(1):16. PMID: 27130633.

• Bautista-Hernandez V, Karamanlidis G, McCully JD, Del Nido PJ. Cellular and Molecular Mechanisms of Low Cardiac Output Syndrome after Pediatric Cardiac Surgery. Curr Vasc Pharmacol. 2016; 14(1):5-13. PMID: 26463990.

• Pacak CA, Preble JM, Kondo H, Seibel P, Levitsky S, Del Nido PJ, Cowan DB, McCully JD. Actin-dependent mitochondrial internalization in cardiomyocytes: evidence for rescue of mitochondrial function. Biol Open. 2015 Apr 10; 4(5):622-6. PMID: 25862247.

• Pacak CA, Hammer PE, MacKay AA, Dowd RP, Wang KR, Masuzawa A, Sill B, McCully JD, Cowan DB. Superparamagnetic iron oxide nanoparticles function as a long-term, multi-modal imaging label for non-invasive tracking of implanted progenitor cells. PLoS One. 2014; 9(9):e108695. PMID: 25250622.

• Preble JM, Pacak CA, Kondo H, MacKay AA, Cowan DB, McCully JD. Rapid isolation and purification of mitochondria for transplantation by tissue dissociation and differential filtration. J Vis Exp. 2014 Sep 06; (91):e51682. PMID: 25225817.

• Black KM, Masuzawa A, Hagberg RC, Khabbaz KR, Trovato ME, Rettagliati VM, Bhasin MK, Dillon ST, Libermann TA, Toumpoulis IK, Levitsky S, McCully JD. Preliminary biomarkers for identification of human ascending thoracic aortic aneurysm. J Am Heart Assoc. 2013 Nov 14; 2(6):e000138. PMID: 24231657.

• Masuzawa A, Black KM, Pacak CA, Ericsson M, Barnett RJ, Drumm C, Seth P, Bloch DB, Levitsky S, Cowan DB, McCully JD. Transplantation of autologously derived mitochondria protects the heart from ischemia-reperfusion injury. . 2013 Apr 01; 304(7):H966-82. PMID: 23355340.

• Friehs I, Cowan DB, Choi YH, Black KM, Barnett R, Bhasin MK, Daly C, Dillon SJ, Libermann TA, McGowan FX, del Nido PJ, Levitsky S, McCully JD. Pressure-overload hypertrophy of the developing heart reveals activation of divergent gene and protein pathways in the left and right ventricular myocardium. . 2013 Mar 01; 304(5):H697-708. PMID: 23262132.

• Black KM, Barnett RJ, Bhasin MK, Daly C, Dillon ST, Libermann TA, Levitsky S, McCully JD. Microarray and proteomic analysis of the cardioprotective effects of cold blood cardioplegia in the mature and aged male and female. Physiol Genomics. 2012 Nov 01; 44(21):1027-41. PMID: 22968637.

• Toumpoulis IK, Oxford JT, Cowan DB, Anagnostopoulos CE, Rokkas CK, Chamogeorgakis TP, Angouras DC, Shemin RJ, Navab M, Ericsson M, Federman M, Levitsky S, McCully JD. Differential expression of collagen type V and XI alpha-1 in human ascending thoracic aortic aneurysms. Ann Thorac Surg. 2009 Aug; 88(2):506-13. PMID: 19632402.

• McCully JD, Bhasin MK, Daly C, Guerrero MC, Dillon S, Liberman TA, Cowan DB, Mably JD, McGowan FX, Levitsky S. Transcriptomic and proteomic analysis of global ischemia and cardioprotection in the rabbit heart. Physiol Genomics. 2009 Jul 09; 38(2):125-37. PMID: 19454556.

• McCully JD, Cowan DB, Pacak CA, Toumpoulis IK, Dayalan H, Levitsky S. Injection of isolated mitochondria during early reperfusion for cardioprotection. . 2009 Jan; 296(1):H94-H105. PMID: 18978192.

• Hsieh YJ, Wakiyama H, Levitsky S, McCully JD. Cardioplegia and diazoxide modulate STAT3 activation and DNA binding. Ann Thorac Surg. 2007 Oct; 84(4):1272-8. PMID: 17888982.

• McCully JD, Rousou AJ, Parker RA, Levitsky S. Age- and gender-related differences in mitochondrial oxygen consumption and calcium with cardioplegia and diazoxide. Ann Thorac Surg. 2007 Mar; 83(3):1102-9. PMID: 17307466.

• Tansey EE, Kwaku KF, Hammer PE, Cowan DB, Federman M, Levitsky S, McCully JD. Reduction and redistribution of gap and adherens junction proteins after ischemia and reperfusion. Ann Thorac Surg. 2006 Oct; 82(4):1472-9. PMID: 16996956.

• McCully JD, Toyoda Y, Wakiyama H, Rousou AJ, Parker RA, Levitsky S. Age- and gender-related differences in ischemia/reperfusion injury and cardioprotection: effects of diazoxide. Ann Thorac Surg. 2006 Jul; 82(1):117-23. PMID: 16798201.

• Rousou AJ, Ericsson M, Federman M, Levitsky S, McCully JD. Opening of mitochondrial KATP channels enhances cardioprotection through the modulation of mitochondrial matrix volume, calcium accumulation, and respiration. . 2004 Nov; 287(5):H1967-76. PMID: 15242834.

• McCully JD, Wakiyama H, Hsieh YJ, Jones M, Levitsky S. Differential contribution of necrosis and apoptosis in myocardial ischemia-reperfusion injury. . 2004 May; 286(5):H1923-35. PMID: 14715509.

• McCully JD, Levitsky S. Mitochondrial ATP-sensitive potassium channels in surgical cardioprotection. Arch Biochem Biophys. 2003 Dec 15; 420(2):237-45. PMID: 14654062.

• Levitsky S, Laurikka J, Stewart RD, Campos CT, Lahey SJ, McCully JD. Mitochondrial DNA deletions in coronary artery bypass grafting patients. Eur J Cardiothorac Surg. 2003 Nov; 24(5):777-84. PMID: 14583312.

• McCully JD, Levitsky S. The mitochondrial K(ATP) channel and cardioprotection. Ann Thorac Surg. 2003 Feb; 75(2):S667-73. PMID: 12607710.

• McCully JD, Wakiyama H, Cowan DB, Federman M, Parker RA, Levitsky S. Diazoxide amelioration of myocardial injury and mitochondrial damage during cardiac surgery. Ann Thorac Surg. 2002 Dec; 74(6):2138-45; discussion 2146. PMID: 12643408.

• Bianchi C, Wakiyama H, Faro R, Khan T, McCully JD, Levitsky S, Szabó C, Sellke FW. A novel peroxynitrite decomposer catalyst (FP-15) reduces myocardial infarct size in an in vivo peroxynitrite decomposer and acute ischemia-reperfusion in pigs. Ann Thorac Surg. 2002 Oct; 74(4):1201-7. PMID: 12400769.

• McCully JD. Oxygenated multidose delivery of crystalloid esmolol cardioplegia as an alternative to high potassium cardioplegia. J Thorac Cardiovasc Surg. 2002 Aug; 124(2):219-20. PMID: 12167779.

• Wakiyama H, Cowan DB, Toyoda Y, Federman M, Levitsky S, McCully JD. Selective opening of mitochondrial ATP-sensitive potassium channels during surgically induced myocardial ischemia decreases necrosis and apoptosis. Eur J Cardiothorac Surg. 2002 Mar; 21(3):424-33. PMID: 11888758.

• Faro R, Toyoda Y, McCully JD, Jagtap P, Szabo E, Virag L, Bianchi C, Levitsky S, Szabo C, Sellke FW. Myocardial protection by PJ34, a novel potent poly (ADP-ribose) synthetase inhibitor. Ann Thorac Surg. 2002 Feb; 73(2):575-81. PMID: 11845877.

• Toyoda Y, Khan S, Chen W, Parker RA, Levitsky S, McCully JD. Effects of NHE-1 inhibition on cardioprotection and impact on protection by K/Mg cardioplegia. Ann Thorac Surg. 2001 Sep; 72(3):836-43; discussion 843-4. PMID: 11565667.

• Stadler B, Phillips J, Toyoda Y, Federman M, Levitsky S, McCully JD. Adenosine-enhanced ischemic preconditioning modulates necrosis and apoptosis: effects of stunning and ischemia-reperfusion. Ann Thorac Surg. 2001 Aug; 72(2):555-63; discussion 563-4. PMID: 11515897.

• Toyoda Y, Levitsky S, McCully JD. Opening of mitochondrial ATP-sensitive potassium channels enhances cardioplegic protection. Ann Thorac Surg. 2001 Apr; 71(4):1281-8; discussion 1288-9. PMID: 11308175.

• McCully JD, Toyoda Y, Uematsu M, Stewart RD, Levitsky S. Adenosine-enhanced ischemic preconditioning: adenosine receptor involvement during ischemia and reperfusion. . 2001 Feb; 280(2):H591-602. PMID: 11158956.

• Sasaki S, Yasuda K, McCully JD, Palombo JD, LoCicero J. Perfusion with lipopolysaccharide negative blood eliminates lipopolysaccharide induced lung injury. ASAIO J. 2001 Jan-Feb; 47(1):45-9. PMID: 11199314.

• Toyoda Y, Friehs I, Parker RA, Levitsky S, McCully JD. Differential role of sarcolemmal and mitochondrial K(ATP) channels in adenosine-enhanced ischemic preconditioning. . 2000 Dec; 279(6):H2694-703. PMID: 11087223.

• Matsuda H, Levitsky S, McCully JD. Inhibition of RNA transcription modulates magnesium-supplemented potassium cardioplegia protection. Ann Thorac Surg. 2000 Dec; 70(6):2107-12. PMID: 11156129.

• Toyoda Y, Di Gregorio V, Parker RA, Levitsky S, McCully JD. Anti-stunning and anti-infarct effects of adenosine-enhanced ischemic preconditioning. Circulation. 2000 Nov 07; 102(19 Suppl 3):III326-31. PMID: 11082409.

• McCully JD, Levitsky S. Alternatives for myocardial protection: adenosine-enhanced ischemic preconditioning. Ann N Y Acad Sci. 1999 Jun 30; 874:295-305. PMID: 10415541.

• McCully JD, Uematsu M, Levitsky S. Adenosine-enhanced ischemic preconditioning provides myocardial protection equal to that of cold blood cardioplegia. Ann Thorac Surg. 1999 Mar; 67(3):699-704. PMID: 10215213.

• Sasaki S, Yasuda K, McCully JD, LoCicero J. Does PGE1 attenuate potassium-induced vasoconstriction in initial pulmonary artery flush on lung preservation? J Heart Lung Transplant. 1999 Feb; 18(2):139-42. PMID: 10194037.

• Sasaki S, Yasuda K, McCully JD, LoCicero J. Calcium channel blocker enhances lung preservation. J Heart Lung Transplant. 1999 Feb; 18(2):127-32. PMID: 10194035.

• McCully JD, Uematsu M, Parker RA, Levitsky S. Adenosine-enhanced ischemic preconditioning provides enhanced cardioprotection in the aged heart. Ann Thorac Surg. 1998 Dec; 66(6):2037-43. PMID: 9930490.

• Uematsu M, Gaudette GR, Laurikka JO, Levitsky S, McCully JD. Adenosine-enhanced ischemic preconditioning decreases infarct in the regional ischemic sheep heart. Ann Thorac Surg. 1998 Aug; 66(2):382-7. PMID: 9725373.

• McCully JD, Uematsu M, Parker RA, Levitsky S. Adenosine-enhanced ischemic preconditioning provides enhanced postischemic recovery and limitation of infarct size in the rabbit heart. J Thorac Cardiovasc Surg. 1998 Jul; 116(1):154-62. PMID: 9671910.

• Matsuda H, McCully JD, Levitsky S. Developmental differences in cytosolic calcium accumulation associated with global ischemia: evidence for differential intracellular calcium channel receptor activity. Circulation. 1997 Nov 04; 96(9 Suppl):II-233-8; discussion II-238-9. PMID: 9386104.

• Tsukube T, McCully JD, Metz KR, Cook CU, Levitsky S. Amelioration of ischemic calcium overload correlates with high-energy phosphates in senescent myocardium. Am J Physiol. 1997 Jul; 273(1 Pt 2):H418-25. PMID: 9249517.

• McCully JD, Levitsky S. Mechanisms of in vitro cardioprotective action of magnesium on the aging myocardium. Magnes Res. 1997 Jun; 10(2):157-68. PMID: 9368237.

• Krukenkamp IB, McCully J, Levitsky S. "Reperfusion Injury" and Myocardial Protection by Cardioplegia: An Opinion. J Thromb Thrombolysis. 1997 Jan; 4(1):131-132. PMID: 10639250.

• McCully JD, Levitsky S. Myocardial protection in the elderly. Biology of the senescent heart. Ann N Y Acad Sci. 1996 Sep 30; 793:305-18. PMID: 8906174.

• Tsukube T, McCully JD, Federman M, Krukenkamp IB, Levitsky S. Developmental differences in cytosolic calcium accumulation associated with surgically induced global ischemia: optimization of cardioplegic protection and mechanism of action. J Thorac Cardiovasc Surg. 1996 Jul; 112(1):175-84. PMID: 8691865.

• McCully JD, Lotz MM, Krukenkamp IB, Levitsky S. A brief period of retrograde hyperthermic perfusion enhances myocardial protection from global ischemia: association with accumulation of Hsp 70 mRNA and protein. J Mol Cell Cardiol. 1996 Feb; 28(2):231-41. PMID: 8729056.

• Sasaki S, Alessandrini F, Lodi R, McCully J, LoCicero J. Improvement of pulmonary graft after storage for twenty-four hours by in vivo administration of lazaroid U74389G: functional and morphologic analysis. J Heart Lung Transplant. 1996 Jan; 15(1 Pt 1):35-42. PMID: 8820081.

• Faulk EA, McCully JD, Hadlow NC, Tsukube T, Krukenkamp IB, Federman M, Levitsky S. Magnesium cardioplegia enhances mRNA levels and the maximal velocity of cytochrome oxidase I in the senescent myocardium during global ischemia. Circulation. 1995 Nov 01; 92(9 Suppl):II405-12. PMID: 7586446.

• Nanji AA, Griniuviene B, Yacoub LK, Sadrzadeh SM, Levitsky S, McCully JD. Heat-shock gene expression in alcoholic liver disease in the rat is related to the severity of liver injury and lipid peroxidation. . 1995 Oct; 210(1):12-9. PMID: 7675793.

• Sasaki S, McCully JD, Palombo JD, Forse RA, LoCicero J. Lung preservation threshold in a compromised septic lung injury model. Ann Thorac Surg. 1995 Oct; 60(4):958-62; discussion 962-3. PMID: 7575002.

• Faulk EA, McCully JD, Tsukube T, Hadlow NC, Krukenkamp IB, Levitsky S. Myocardial mitochondrial calcium accumulation modulates nuclear calcium accumulation and DNA fragmentation. Ann Thorac Surg. 1995 Aug; 60(2):338-44. PMID: 7544101.

• Sasaki S, McCully JD, Alessandrini F, LoCicero J. Impact of initial flush potassium concentration on the adequacy of lung preservation. J Thorac Cardiovasc Surg. 1995 Jun; 109(6):1090-5; discussion 1095-6. PMID: 7776673.

• Nanji AA, Griniuviene B, Sadrzadeh SM, Levitsky S, McCully JD. Effect of type of dietary fat and ethanol on antioxidant enzyme mRNA induction in rat liver. J Lipid Res. 1995 Apr; 36(4):736-44. PMID: 7616120.

• McCully JD, Myrmel T, Lotz MM, Krukenkamp IB, Levitsky S. The rapid expression of myocardial hsp 70 mRNA and the heat shock 70 kDa protein can be achieved after only a brief period of retrograde hyperthermic perfusion. J Mol Cell Cardiol. 1995 Mar; 27(3):873-82. PMID: 7602605.

• Myrmel T, McCully JD, Malikin L, Krukenkamp IB, Levitsky S. Heat-shock protein 70 mRNA is induced by anaerobic metabolism in rat hearts. Circulation. 1994 Nov; 90(5 Pt 2):II299-305. PMID: 7955269.

• Tsukube T, McCully JD, Faulk EA, Federman M, LoCicero J, Krukenkamp IB, Levitsky S. Magnesium cardioplegia reduces cytosolic and nuclear calcium and DNA fragmentation in the senescent myocardium. Ann Thorac Surg. 1994 Oct; 58(4):1005-11. PMID: 7944743.

• McCully JD, Tsukube T, Ataka K, Krukenkamp IB, Feinberg H, Levitsky S. Myocardial cytosolic calcium accumulation during ischemia/reperfusion: the effects of aging and cardioplegia. J Card Surg. 1994 May; 9(3 Suppl):449-52. PMID: 8069034.

• Ataka K, Chen D, McCully J, Levitsky S, Feinberg H. Magnesium cardioplegia prevents accumulation of cytosolic calcium in the ischemic myocardium. J Mol Cell Cardiol. 1993 Dec; 25(12):1387-90. PMID: 8158658.

• McCully JD, Wang RX, Kellam B, Sole MJ, Liew CC. Isolation and characterization of a previously unrecognized myosin heavy chain gene present in the Syrian hamster. J Mol Biol. 1991 Apr 20; 218(4):657-65. PMID: 2023240.

• McCully JD, Mably JD, Sole MJ, Liew CC. RNA transcription and translation in the hearts of normal and cardiomyopathic Syrian hamsters. Biochem Cell Biol. 1991 Jan; 69(1):88-92. PMID: 1710470.

• McCully JD, Liew CC. RNA transcription in myocardial-cell nuclei during postnatal development. A study establishing an assay system for transcription in vitro. Biochem J. 1988 Dec 01; 256(2):441-5. PMID: 2464996.

• McCully JD, Jandreski MA, Liew J, Sole MJ, Liew CC. Construction of cosmid genomic libraries for the normal and myopathic Syrian hamsters. Biochem Cell Biol. 1987 Nov; 65(11):997-1000. PMID: 2831916.

• McCully JD, Taylor PB, Morrison NL. Alterations in myocardial RNA synthesis and RNA polymerase activity during normal growth. Can J Physiol Pharmacol. 1983 Apr; 61(4):341-8. PMID: 6190543.