"Targeting aging and brain health — one worm at a time"

The KM Lab (Meemon Lab) is a university-based research unit dedicated to advancing the understanding of biological mechanisms underlying aging, metabolic disorders such as obesity, and neurodegenerative diseases including Alzheimer’s and Parkinson’s. Using Caenorhabditis elegans (C. elegans), a powerful and widely established model organism in biological and medical research, our lab explores key molecular and cellular pathways involved in lifespan regulation, metabolic health, and neural degeneration.

A major focus of the KM Lab is to develop novel strategies for the prevention and treatment of age-related, metabolic, and neurodegenerative conditions. A key area involves exploring natural compounds and plant-derived extracts for their potential in anti-aging, anti-obesity, and neuroprotective therapies. We investigate how these bioactives can delay aging, improve metabolic health, and preserve or restore neural function in disease models.

Using an integrated approach combining molecular biology, genetics, biochemistry, and advanced imaging, we aim to deepen understanding of aging mechanisms and develop innovative therapeutic interventions.

The KM Lab is led by Associate Professor Dr. Krai Meemon, Department of Anatomy, Faculty of Science, Mahidol University, and is recognized as one of Thailand's leading research groups in C. elegans-based biomedical science.

Recent Publications - 2025

CONGRATULATIONS