News and Publications

News

Dec 2022 : Mr W Yenjai (Champ) was awarded the Graduate Researcher Development Grant from the National Research Council of Thailand (NRCT) (THB 300,000) 

Nov 2022 : SC was promoted to Assistant Professor in Organic Chemistry.

July 2022 : SC was awarded the Research Grant for New Scholar from the Ministry of Higher Education, Science, Research and Innovation (PI: THB 600,000) 

Jan 2022 : Welcome Mr P Kanjanasirirat (M) as the first PhD student to the group. He will be working on a drug repurposing project targeting the 3D brain tumour.

Dec 2021 : SC was awarded the Strategic Fund research grant (COVID-19) from the National Research Council of Thailand (NRCT) (PI: THB 955,000) - Feb 22 - May 23

Jan 2021 : Welcome Ms V Tantivess (Fern) as an undergraduate intern to the group. She now continues her undergrad study at Brown. Wish her all the best.

Jan 2021 : Welcome Mr W Yenjai (Champ) as the first MSc student to the group. He will be working on a chemoproteomics project focusing on the application of thermal proteome profiling (TPP). He passed his thesis proposal in Apr 2022.

Dec 2020 : SC was awarded the Fundamental Fund research grant from Thailand Science Research and Innovation (TSRI) via Mahidol University (PI: THB 500,000) - Oct 20 - Sep 21

Nov 2020 : SC was awarded the research grant from TCELS via ECDD under the NPDD collaboration between Takeda and TCELS  (Co-PI: THB 1,500,000) - Nov 20 - Sep 21

Sep 2020 : Welcome Mr P Schlaeppi as our first undergraduate intern to the group. In his 10-week internship, he learnt how to synthesise and purify the target molecules. He now continues his undergrad study at Cornell. Wish him luck.

Sep 2020 : SC was awarded the research grant from TCELS via ECDD entitled Development of Phenotypic Screening Platform of Drugs Against Novel Coronavirus (COVID-19) (2nd phase) (Co-PI: THB 800,000) - Sep 20 - Mar 21

Aug 2020 : Welcome Ms D Lohawittayanan (Ing) as a research assistant to the group. 

May 2020 : SC was awarded the PMU-C Grant Fiscal Year 2020 from the PMU-C (Co-PI: THB 1,900,000) - Sep 20 - Sep 21

Feb 2020 : SC was awarded the New Researcher Grant from Mahidol University (PI : THB 250,000) with the Supplementary Grant from Faculty of Science (THB 60,000) - Feb 20 - Jan 21

Nov 2019 : SC was awarded the New Equipment Grant from Faculty of Science, Mahidol University (THB 197,950)

Sep 2019 : The group was established at K617 Laboratory under the School of Bioinnovation using the lab space belonged to the Centre for Neuroscience, Faculty of Science, Mahidol University.

Publications

Most Recent Articles from Scopus

Rational Design and Lead Optimisation of Potent Antimalarial Quinazolinediones and Their Cytotoxicity against MCF-7

Molecules / April 2023

Receptor binding protein of prophage reversibly recognizes the low-molecular weight subunit of the surface-layer protein SlpA in Clostridioides difficile

Frontiers in Microbiology / 14 October 2022

A Concise Synthesis towards Antimalarial Quinazolinedione TCMDC-125133 and Its Anti-Proliferative Activity against MCF-7

MolBank / June 2022

A new strategy for hit generation: Novel in cellulo active inhibitors of CYP121A1 from Mycobacterium tuberculosis via a combined X-ray crystallographic and phenotypic screening approach (XP screen)

European Journal of Medicinal Chemistry / 15 February 2022

Development of Inhibitors of SAICAR Synthetase (PurC) from Mycobacterium abscessus Using a Fragment-Based Approach

ACS Infectious Diseases / 11 February 2022

Frontiers in antibiotic alternatives for Clostridioides difficile infection

World Journal of Gastroenterology / 14 November 2021

Anti-SARS-CoV-2 Activity ofAndrographis paniculataExtract and Its Major Component Andrographolide in Human Lung Epithelial Cells and Cytotoxicity Evaluation in Major Organ Cell Representatives

Journal of Natural Products / 23 April 2021

High-content screening of Thai medicinal plants reveals Boesenbergia rotunda extract and its component Panduratin A as anti-SARS-CoV-2 agents

Scientific Reports / December 2020

Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides

Nature Communications / 1 December 2019

Structure-guided fragmentbased drug discovery at the synchrotron: Screening binding sites and correlations with hotspot mapping

Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences / 17 June 2019

Corrigendum to: A Click Chemistry-Based Proteomic Approach Reveals that 1,2,4-Trioxolane and Artemisinin Antimalarials Share a Common Protein Alkylation Profile (Chem. Int. Ed, (2016), 55, 10.1002/anie.201512062)

Angewandte Chemie - International Edition / 26 August 2016

A click chemistry-based proteomic approach reveals that 1,2,4-trioxolane and artemisinin antimalarials share a common protein alkylation profile

Angewandte Chemie - International Edition / 23 May 2016

Artemisinin activity-based probes identify multiple molecular targets within the asexual stage of the malaria parasites Plasmodium falciparum 3D7

Proceedings of the National Academy of Sciences of the United States of America / 23 February 2016

2-Pyridylquinolone antimalarials with improved antimalarial activity and physicochemical properties

MedChemComm / 1 July 2015

Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria

Proceedings of the National Academy of Sciences of the United States of America / 22 May 2012

Identification, design and biological evaluation of bisaryl quinolones targeting Plasmodium falciparum type II NADH:Quinone oxidoreductase (PfNDH2)

Journal of Medicinal Chemistry / 8 March 2012

Identification, design and biological evaluation of heterocyclic quinolones targeting plasmodium falciparum Type II NADH:Quinone oxidoreductase (PfNDH2)

Journal of Medicinal Chemistry / 8 March 2012