The SynGlyco Research Group

@MAHIDOL UNIVERSITY

The SynGlyco Research Lab conducts advanced experimentation in Synthetic Biology and Glycoengineering.

Research

A schematic diagram illustrating the process of cell-free glycoprotein synthesis. The left side depicts a green bacterium, representing the source of biological machinery. The right side shows a beaker labeled "cell-free extract" being fed with inputs labeled "DNA," "Amino Acids," and "Energy". Arrows from both the bacterium and the beaker point to the center, where a synthesized protein structure with attached geometric sugar chains (glycans) is displayed.

Welcome to the SynGlyco Lab, where we engineer the sugar code of life. We combine cell-free synthetic biology, glycoengineering, and bioprocess innovation to study, design, and construct glycan structures with precision. Our research spans cell-based and cell-free systems to tackle fundamental questions in glycobiology and develop next-generation biotechnologies. From programming cellular glycosylation pathways to building cell-free glycoprotein synthesis platforms, we're creating new tools to decode, design, and deploy glycans for applications in diagnostics, therapeutics, and beyond. Based in the Department of Biotechnology at Mahidol University, we're building a modular approach to understanding and harnessing one of most complex biomolecules in Nature - carbohydrates.

More about our research →

Resources

We believe in open science. All our published protocols and reagents are available upon reasonable requests. Please contact Dr. Thapakorn.

Publications

While the SynGlyco Lab is just getting started at Mahidol University, our foundational research has been published in leading international journals. You can find a complete and up-to-date list of the Principal Investigator's publications here.

Publications→

Our team

We are actively recruiting passionate students (Senior Projects, M.Sc., Ph.D.) and postdocs to join us in establishing this new program. If you are interested in working at the interface of biology and engineering, we want to hear from you.

Meet the team→

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