Stimulant drugs, such as amphetamines and cocaine, "accelerate" the activity of the central nervous system.
The combination of different stimulants can multiply this effect, putting more stress on the body, especially the heart and other vital organs
Depressive drugs, such as alcohol and benzodiazepines, opioid drugs such as heroin and oxycodone and cannabis, can "slow down" the central nervous system.
Psychedelics, such as LSD, magic mushrooms, and mescaline, distort a person's perception of reality. MDMA and cannabis can also have some hallucinogenic effects.
Taking these drugs can lead to seeing or hearing things that are not really there or experiencing real things in a distorted way.