Founded in the XIII century by the Carmelites as a convent with an annexed church, then destroyed in a fire in 1330, the building of Santa Maria del Carmine was rebuilt in 1400. Over time, it has been repaired multiple times until it reached the final look that we can admire today.
In 1268 the Carmelites built a convent near the Sforza Castle, together with an annexed church. However, the latter was destroyed in a fire in 1330. The rebuilt church was abandoned before the end of the century, after the friars moved to another friary. The church was rebuilt once again starting from 1400, under the design of friar Bernardo da Venezia. In the mid-15th century, the church became a favourite destination for aristocratic burials, as is testified by the numerous noble tombs in the chapels. Finally, in the 17th century the presbytery was remade in the baroque style. The current façade was designed by Carlo Maciachini and was completed in 1880.
The interior has a nave and two aisles, which are covered by crossed vaulted ceilings and separated by large circular pillars in earthenware tile or simple stone. In the naves and transepts there are several artworks, including works by Camillo Procaccini depicting St Charles Borromeo Praying (1585) and other works by the painter in the Chapel of Madonna del Carmine, as well as a Madonna statue at the altar. The high altar features a small temple inspired by the one that is to be found in the Milan Cathedral.