2025

You E, Patel BK, Rojas AS, Sun S, Ho NI, Phillips IE, Raabe MJ, Song Y, Xu KH, Kocher JR, Richieri PM, Taylor MS, Nieman LT, Greenbaum BD, Ting DT*. LINE-1 ORF1p mimics viral immune evasion mechanisms in pancreatic cancer. Cancer Discovery 2025 May 2. doi.org/10.1158/2159-8290.CD-24-1317  IF: 30.6

2024 

You E, Danaher P, Lu C, Sun S, Zou L, Philips IE, Rojas AS, Ho NI, Song Y, Raabe MJ, Xu KH, Richieri PM, Li H, Aston N, Porter RL, Patel BK, Nieman LT, Schurman N, Hudson BM, North K, Church SE, Deshpande V, Liss AS, Kim TK, Kim Y, Greenbaum BD, Aryee MJ*, Ting DT*. Disruption of cellular plasticity by repeat RNAs in human pancreatic cancer. Cell 2024 Dec 12;187(25):7232-7247. doi: 10.1016/j.cell.2024.09.024. IF: 45.5

Sun S#*, You E#, Hong J, Hoyos D, Priore ID, Tsanov KM, Mattagajasingh O , Gioacchino AD, Marhon SA, Chacon-Barahona J, Li H, Jiang H, Ly BH, Rojas AS, Song Y, Lang ER, Nieman LT, Patel BK, Murali R, Chanda P, Karacay A, Vabret N, Carvalho DD, Zenklusen D, LaCava J, Lowe SW, Ting DT, Iacobuzio-Donahue CA, Solovyov A, Benjamin D. Greenbaum BD*. Cancer cells restrict immunogenicity of retrotransposon expression via distinct mechanisms. Immunity 2024 Dec 10;57(12):2879-2894. doi: 10.1016/j.immuni.2024.10.015. #Equal contribution.  IF: 25.5

Choi JH#, Jeong J#, Kim J, You E, Keum S, Song S, Hwang YE, Ji M, Park KS, Rhee S*. Genetic disruption of ATAT1 causes RhoA downregulation through abnormal truncation of C/EBPβ. BMB Reports 2024 Jun;57(6):293-298. doi: 10.5483/BMBRep.2023-0230. #Equal contribution. IF: 2.9

2022

Porter RL#, Sun S#, Flores MN, Berzolla E, You E, Phillips IE, Kc N, Desai N, Tai EC, Szabolcs A, Lang ER, Pankaj A, Raabe MJ, Thapar V, Xu KH, Nieman LT, Rabe DC, Kolin DL, Stover EH, Pepin D, Stott SL, Deshpande V, Liu JF, Solovyov A, Matulonis UA, Greenbaum BD*, Ting DT*. Satellite repeat RNA expression in epithelial ovarian cancer associates with a tumor-immunosuppressive phenotype. Journal of Clinical Investigation 2022 Aug 15;132(16). 

doi: 10.1172/JCI155931. #Equal contribution. IF: 15.9

Rajurkar M#, Parikh AR#, Solovyov A#, You E, Kulkarni AS, Chu C, Xu KH, Jaicks C, Taylor MS, Wu C, Alexander KA, Good CR, Szabolcs A, Gerstberger S, Tran AV, Xu N, Ebright RY, Van Seventer EE, Vo KD, Tai EC, Lu C, Joseph-Chazan J, Raabe MJ, Nieman LT, Desai N, Arora KS, Ligorio M, Thapar V, Cohen L, Garden PM, Senussi Y, Zheng H, Allen JN, Blaszkowsky LS, Clark JW, Goyal L, Wo JY, Ryan DP, Corcoran RB, Deshpande V, Rivera MN, Aryee MJ, Hong TS, Berger SL, Walt DR, Burns KH, Park PJ, Greenbaum BD*, Ting DT*. Reverse transcriptase inhibition disrupts repeat element life cycle in colorectal cancer. Cancer Discovery 2022 Jun 2;12(6):1462-1481. doi: 10.1158/2159-8290.CD-21-1117. #Equal contribution. IF: 28.2

You E#, Jeong J#, Lee J, Keum S, Hwang YE, Choi JH*, Rhee S*. Casein kinase 2 promotes the TGF-β-induced activation of α-tubulin acetyltransferase 1 in fibroblasts cultured on a soft matrix. BMB Reports 2022 Apr;55(4):192-197. doi: 10.5483/BMBRep.2022.55.4.021. #Equal contribution. IF: 3.8

2020

Kang DH, Lee TJ, Kim JW, Shin YS, Kim JD, Ryu SW, Ryu S, Choi YH, Kim CH, You E, Rhee S, Song KS*. Down-regulation of diesel particulate matter-induced airway inflammation by the PDZ motif peptide of ZO-1. J Cell Mol Med 2020 Oct;24(20):12211-12218. doi: 10.1111/jcmm.15843. IF: 5.31

You E, Ko P, Jeong J, Keum S, Kim JW, Seo YJ, Song WK, Rhee S*. Dynein-mediated nuclear translocation of yes-associated protein through microtubule acetylation controls fibroblast activation. Cellular and Molecular Life Sciences 2020 Oct;77(20):4143-4161. doi: 10.1007/s00018-019-03412-x. IF: 9.261

Kwon A, Lee GB, Park T, Lee JH, Ko P, You E, Ahn JH, Eom SH, Rhee S*, Song WK*. Potent small-molecule inhibitors targeting acetylated microtubules as anticancer agents triple-negative breast cancer. Biomedicines 2020 Sep 9;8(9). doi: 10.3390/biomedicines8090338. IF: 6.081

2019

Kwon A, Chae IH, You E, Kim SH, Ahn SY, Lee OJ, Park ZY, Rhee S, Huh YH*, Song WK*. Extra domain A-containing fibronectin expression in Spin90-deficient fibroblasts mediates cancer-stroma interaction and promotes breast cancer progression. Journal of Cellular Physiology 2020 May;235(5):4494-4507. doi: 10.1002/jcp.29326. IF: 6.384

Lee J#, Ko P#, You E, Jeong J, Keum S, Kim J, Rahman M, Lee DH, Rhee S*. Shwachman-Bodian-Diamond syndrome protein desensitizes breast cancer cells to apoptosis in stiff matrices by repressing the caspase 8-mediated pathway. Animal Cells and Systems (Seoul) 2019 Sep 23(6):414-421. doi: 10.1080/19768354.2019.1666030. #Equal contribution. IF: 0.907

You E, Huh YH, Lee J, Ko P, Jeong J, Keum S, Kim J, Kwon A, Song WK, Rhee S*. Downregulation of SPIN90 promotes fibroblast activation via periostin-FAK-ROCK signaling module. Journal of Cellular Physiology 2019 Jun;234(6):9216-9224. doi: 10.1002/jcp.27600. IF: 5.546

2018

Jeong J#, Keum S#, Kim D, You E, Ko P, Lee J, Kim J, Kim JW, Rhee S*. Spindle pole body component 25 homolog expressed by ECM stiffening is required for lung cancer cell proliferation. Biochemical and Biophysical Research Communications 2018 Jun 12;500(4):937-943. doi: 10.1016/j.bbrc.2018.04.205. #Equal contribution. IF: 2.705

2017

You E#, Huh YH#, Kwon A, Kim SH, Chae IH, Lee OJ, Ryu JH, Park MH, Kim GE, Lee JS, Lee KH, Lee YS, Kim JW, Rhee S*, Song WK*. SPIN90 Depletion and Microtubule Acetylation Mediate Stromal Fibroblast Activation in Breast Cancer Progression. Cancer Research 2017 Sep 1;77(17):4710-4722. 

doi: 10.1158/0008-5472.CAN-17-0657. #Equal contribution IF: 9.130

Kim D#, You E#, Jeong J, Ko P, Kim JW, Rhee S*. DDR2 controls the epithelial-mesenchymal-transition-related gene expression via c-Myb acetylation upon matrix stiffening. Scientific Reports 2017 Jul 28;7(1):6847. doi: 10.1038/s41598-017-07126-7. # Equal contribution. IF: 4.122

Oh S, You E, Ko P, Jeong J, Keum S, Rhee S*. Genetic disruption of tubulin acetyltransferase, αTAT1, inhibits proliferation and invasion of colon cancer cells through decreases in Wnt1/β-catenin signaling. Biochemical and Biophysical Research Communications 2017 Jan 1;482(1):8-14. doi: 10.1016/j.bbrc.2016.11.039. IF: 2.559

~2016

Choi IW, Ahn do W, Choi JK, Cha HJ, Ock MS, You E, Rhee S, Kim KC, Choi YH, Song KS*. Regulation of Airway Inflammation by G-protein Regulatory Motif Peptides of AGS3 protein. Scientific Reports 2016 Jun 7;6:27054. doi: 10.1038/srep27054. IF: 4.259

Ko P, Kim D, You E, Jung J, Oh S, Kim J, Lee KH, Rhee S*. Extracellular Matrix Rigidity-dependent Sphingosine-1-phosphate Secretion Regulates Metastatic Cancer Cell Invasion and Adhesion. Scientific Reports 2016 Feb 15;6:21564. doi: 10.1038/srep21564. IF: 4.259

Kim D, Ko P, You E, Rhee S*. The intracellular juxtamembrane domain of discoidin domain receptor 2 (DDR2) is essential for receptor activation and DDR2-mediated cancer progression. International Journal of Cancer 2014 Dec 1;135(11):2547-57. doi: 10.1002/ijc.28901. IF: 5.085

You E, Park S, Kim D, Jung J, Ko P, Park CM, Rhee S*. Role of Intracellular juxtamembrane domain of discoidin domain receptor 2 in focal adhesion formation. Animal Cells and Systems 2014 Nov 10;18(6):372-379. doi: 10.1080/19768354.2014.969770. IF: 0.440

Kim D, You E, Min NY, Lee KH, Kim HK, Rhee S*. Discoidin domain receptor 2 regulates the adhesion of fibroblasts to 3D collagen matrices. International Journal of Molecular Medicine 2013 May;31(5):1113-8. doi: 10.3892/ijmm.2013.1320. IF: 1.880

Kim D, You E, Rhee S*. Dynein regulates cell migration depending on substrate rigidity. International Journal of Molecular Medicine 2012 Mar;29(3):440-6. doi: 10.3892/ijmm.2011.867. IF: 1.957