Selected Publications

A human antibody against human endothelin receptor type A that exhibits antitumor potency

Exp. Mol. Med. 2021 Sep;53(9):1437-1448.

How Do We Study the Dynamic Structure of Unstructured Proteins: A Case Study on Nopp140 as an Example of a Large, Intrinsically Disordered Protein.

Int J Mol Sci. 2018 Jan 27;19(2). pii: E381.

Determination of the endothelin-1 recognition sites of endothelin receptor type A by the directed-degeneration method.

Sci Rep. 2017 Aug 8;7(1):7577.

Preparation of functional human lysophosphatidic acid receptor 2 using a P9∗ expression system and an amphipathic polymer and investigation of its in vitro binding preference to Gα proteins.

Biochem Biophys Res Commun. 2017 May 20;487(1):103-108

Overexpression and functional stabilization of recombinant human lysophosphatidic acid receptor 1 using an amphiphatic polymer

Bull. Korean Chem. Soc, 2017 38(1), pp. 63-69

Crystal structure of a putative oligopeptide-binding periplasmic protein from a hyperthermophile.

Extremophiles. 2016 Sep;20(5):723-31.

Biophysical characterization of the structural change of Nopp140, an intrinsically disordered protein, in the interaction with CK2α.

Biochem Biophys Res Commun. 2016 Aug 19;477(2):181-7.

Biochemical and molecular modeling studies of the interaction between human CEP55 and TEX14

Bull. Korean Chem. Soc, 2016 37(6), pp. 847-854

Noncanonical DNA-binding mode of repressor and its disassembly by antirepressor.

Proc Natl Acad Sci U S A. 2016 May 3;113(18):E2480-8

Structural and biochemical insights into the role of testis-expressed gene 14 (TEX14) in forming the stable intercellular bridges of germ cells.

Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):12372-7.

Structural consequences of aglycosylated IgG Fc variants evolved for FcγRI binding.

Mol Immunol. 2015 Oct;67(2 Pt B):350-6

Beta-amyloid oligomers activate apoptotic BAK pore for cytochrome c release.

Biophys J. 2014 Oct 7;107(7):1601-8.

Swath-based comparative proteomic analysis of the mycobacterium bovis bcg-korea strain

Bull. Korean Chem. Soc, 2014 35(3), pp. 933-937

Identification of inhibitors against bak pore formation using an improved in vitro assay system

Bull. Korean Chem. Soc, 2014 35(2), pp. 419-424

An amphipathic polypeptide derived from poly-γ-glutamic acid for the stabilization of membrane proteins.

Protein Sci. 2014 Dec;23(12):1800-7.

Comprehensive proteome analysis of the excretory/secretory proteins of toxoplasma gondii

Bull. Korean Chem. Soc, 2014 35(10), pp. 3071-3076

Rhoptry protein 6 from Toxoplasma gondii is an intrinsically disordered protein.

Protein Expr Purif. 2014 Sep;101:146-51.

Structural and functional insights into the regulation mechanism of CK2 by IP6 and the intrinsically disordered protein Nopp140.

Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19360-5.

Selective detection and automated counting of fluorescently-labeled chrysotile asbestos using a dual-mode high-throughput microscopy (DM-HTM) method.

Sensors (Basel). 2013 May 2;13(5):5686-99.

Identification of novel irreversible inhibitors of UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) from Haemophilus influenzae.

J Microbiol Biotechnol. 2013 Mar;23(3):329-34.

Bacterially expressed human serotonin receptor 3A is functionally reconstituted in proteoliposomes.

Protein Expr Purif. 2013 Apr;88(2):190-5.

Fragment-based discovery of novel and selective mPGES-1 inhibitors Part 1: identification of sulfonamido-1,2,3-triazole-4,5-dicarboxylic acid.

Bioorg Med Chem Lett. 2013 Jan 1;23(1):75-80.

Identification of novel mPGES-1 inhibitors through screening of a chemical library.

Bioorg Med Chem Lett. 2012 Dec 15;22(24):7335-9.

Purification and characterization of recombinant human endothelin receptor type A.

Protein Expr Purif. 2012 Jul;84(1):14-8.

Mitoxantrone binds to Nopp140, an intrinsically unstructured protein, and modulate its interaction with protein kinase CK2

Bull. Korean Chem. Soc, 2012 33(6), pp. 2005-2011

Kinetic properties of wild-type and C117D mutant UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) from haemophilus influenzae

Bull. Korean Chem. Soc, 2011 32(8), pp. 2549-2552

Identification of dinitrotoluene selective peptides by phage display cloning

Bull. Korean Chem. Soc, 2010 31(12), pp. 3703-3706

Blockade of LTB4-induced chemotaxis by bioactive molecules interfering with the BLT2-Galphai interaction.

Biochem Pharmacol. 2010 May 15;79(10):1506-1515

Development of a coupled enzyme assay method for microsomal prostaglandin E synthase activity

Bull. Korean Chem. Soc, 2010 31(2), pp. 384-388

Inhibitory mechanism of novel inhibitors of UDP-N-acetylglucosamine enolpyruvyl transferase from Haemophilus influenzae.

J Microbiol Biotechnol. 2009 Dec;19(12):1582-9.

A cell-based method to monitor the interaction between hepatitis B virus capsid and surface proteins

Bull. Korean Chem. Soc, 2009 30(3), pp. 577-581

Functional reconstitution of the human serotonin receptor 5-HT(6) using synthetic transmembrane peptides.

Biochem Biophys Res Commun. 2009 Dec 18;390(3):815-20.

Expression and purification of human mPGES-1 in E. coli and identification of inhibitory compounds from a drug-library.

BMB Rep. 2008 Nov 30;41(11):808-13.

Characterization of the InsP6-dependent interaction between CK2 and Nopp140.

Biochem Biophys Res Commun. 2008 Nov 14;376(2):439-44.

Activation of NF-kappaB by alloferon through down-regulation of antioxidant proteins and IkappaBalpha.

Mol Cell Biochem. 2008 Jun;313(1-2):91-102.

Interaction and assembly of HBV structural proteins: novel target sites of anti-HBV agents.

Infect Disord Drug Targets. 2007 Sep;7(3):251-6. Review.

An inhibitory compound against the interaction between G alpha(s) and the third intracellular loop region of serotonin receptor subtype 6 (5-HT6) disrupts the signaling pathway of 5-HT6.

Exp Mol Med. 2007 Jun 30;39(3):335-42.

Doxorubicin binds to un-phosphorylated form of hNopp140 and reduces protein kinase CK2-dependent phosphorylation of hNopp140.

J Biochem Mol Biol. 2006 Nov 30;39(6):774-81.

Protein kinase CK2 is inhibited by human nucleolar phosphoprotein p140 in an inositol hexakisphosphate-dependent manner.

J Biol Chem. 2006 Dec 1;281(48):36752-7.

Purification and characterization of a serine protease from Cucumis trigonus Roxburghi.

Phytochemistry. 2006 May;67(9):870-5.

Identification of compounds that inhibit the interaction between core and surface protein of hepatitis B virus.

Antiviral Res. 2006 Jun;70(2):85-90.

Characterization of acetohydroxyacid synthase from Mycobacterium tuberculosis and the identification of its new inhibitor from the screening of a chemical library.

FEBS Lett. 2005 Aug 29;579(21):4903-10.

Molecular analysis of the interaction between the intracellular loops of the human serotonin receptor type 6 (5-HT6) and the alpha subunit of GS protein.

Biochem Biophys Res Commun. 2005 Apr 8;329(2):684-92.

High-throughput screening method of inhibitors that block the interaction between 2 helical regions of HIV-1 gp41.

J Biomol Screen. 2005 Feb;10(1):13-9.

Identification and characterization of a novel angiostatin-binding protein by the display cloning method.

J Biochem Mol Biol. 2004 Mar 31;37(2):159-66.

Substitution of aspartic acid with glutamic acid increases the unfolding transition temperature of a protein.

Biochem Biophys Res Commun. 2004 Jul 30;320(3):900-6.

Quantitative analysis of the interaction between the envelope protein domains and the core protein of human hepatitis B virus.

Biochem Biophys Res Commun. 2004 Jul 2;319(3):959-66.

Purification and characterization of human nucleolar phosphoprotein 140 expressed in Escherichia coli.

Protein Expr Purif. 2003 Oct;31(2):260-4.

Crystallization and preliminary X-ray analysis of the Mj0684 gene product, a putative aspartate aminotransferase, from Methanococcus jannaschii.

Acta Crystallogr D Biol Crystallogr. 2003 Mar;59(Pt 3):563-5.

HIV gp41 binding phenolic components from Fraxinus sieboldiana var. angustata.

Planta Med. 2002 Nov;68(11):1034-6.

Identification of hNopp140 as a binding partner for doxorubicin with a phage display cloning method.

Chem Biol. 2002 Feb;9(2):157-62.

Insertion of a Coiled-Coil Peptide from Influenza Virus Hemagglutinin into Membranes

Science, 1994, 266, 274-276