Research

Hydration analysis in biological tissues

High wavenumber Raman signals, including water, from biological tissues can be analyzed using the Raman spectrometer based on NIR excitation (850-880 nm) and InGaAs detector.

Examples include:

  • O-H group signals from hard dental tissues



  • O-H group signals from animal skin

Wide-field Raman imaging for caries detection

Wide field Raman imaging to acquire full scale tooth surface images ~7 mm in diameter.

Nonlinear Optical Imaging

High-sensitivity nonlinear optical microspectroscopy system integrating coherent anti-Stokes Raman scattering (CARS), second harmonic generation (SHG), and two-photon absorption fluorescence.