Even without a premium account - Kami is a great way for students to edit PDF and for teachers to offer students feedback on their work.
Floop
Floop is a great site for peer-editing, student feedback, and essay writing. Teachers can save comments that they make often to drag and drop into student papers!
Cells Alive
Cells Alive! contains multiple interactive models, games, and other resources for Science students
NowComment
Upload a document and allow students to comment on their own devices, answer questions, and collaborate
Smithsonian Open Access
Gives access to over 3 million items within the Smithsonian Museum
Rocks & Minerals Virtual Labs
Virtual labs curated by Mrs. Vislosky relating to rocks and minerals