Internship

Project Summary

Breast cancer is common and affects 1 in 8 women. One third of patients who undergo axillary lymph node removal as part of the treatment of breast cancer experience lymphedema. It is estimated that lymphedema affects 5 million Americans. Lymphedema is characterized by progressive arm swelling that hinders quality of life, reduces mobility, and increases risk for infections. There is no cure for lymphedema and current treatments are variably effective. Therefore, the goal of this laboratory is to study novel prevention and management strategies for lymphedema. The current study is to evaluate the effect of dermal lymphatic preservation in the development of lymphedema.


About the Internship

Workplace

General Description: While chronic lymphedema is a known issue that can occur from birth, begin after surgery,  or develop over time, there is little that can be done to cure it once it begins, and patients are often stuck only being able to treat the symptoms. Dr. Hassanein's research focuses on what kind of surgeries and techniques patients may be able to utilize to prevent or treat chronic lymphedema.

Elevator Pitch:  I am interning with Dr. Al Hassanein in a lab focused on treating and preventing chronic lymphedema, which can occur after breast cancer surgical treatment. Lymphedema involves the inflammation of the lymphatic tissue in the body, usually caused by the disruption of lymphatic channels that can occur during unrelated surgeries. This research will help mostly by preventing the onset of lymphedema following a surgery where chronic lymphedema has historically been an issue. In the lab, we work with live mice, inducing lymphedema and observing the outcome. I often work with the mice, caring for their day to day needs, which can sometimes be difficult. 

204 lymphoedema images, stock photos, 3D objects, & vectors. Shutterstock. (n.d.). https://www.shutterstock.com/search/lymphoedema


This image depicts the different stages and severities of lymphedema. As disruption of lymphatics increases, as does the associated inflammation.


Successes and Challenges

Successes

Challenges