Publicaciones

A secondary structure within small peptides guiding spontaneous self-aggregation and nanoparticle formation.

Daniel Martínez-Flores, Alicia Sampieri, Alan Juárez-Barragán, Armando Hernández-García, Luis Vaca. Nanoscale Advances (2025).

Optimizing Heterologous Production of CRISPR-AsCas12a Protein in Escherichia coli.

Orlando S Goméz-Quintero, Melissa D Morales-Moreno, Erick G Valdés-Galindo, Rosa Elena Cárdenas-Guerra, Armando Hernández-García. PrePrint ResearchSquare.

Protocolo Público de un Método de Detección de SARS-CoV-2 con CRISPR-Cas12a.

M.D. Morales-Moreno, A. Hernandez-Garcia. Ago 2024.

https://drive.google.com/file/d/11Jubqvxqvg0lGGet-KYGUK6kOg6R9IzN/view?usp=drive_link

Creating Artificial Viruses Using Self-assembled Proteins and Polypeptides.

D.S. Moreno-Gutierrez, X. del Toro-Rios, A. Hernandez-Garcia. In: M. Comas-Garcia, S. Rosales-Mendoza (eds). Physical Virology: From the State-of-the-Art Research to the Future of Applied Virology. 2023, Springer Series in Biophysics, Vol 24, 95-118.

Multiplex gRNAs synergically enhance detection of SARS-CoV-2 by CRISPR-Cas12a.

M.D. Morales-Moreno, E.G. Valdés-Galindo, M.M. Reza, T. Fiordelisio, J. Peon, A. Hernandez-Garcia. The CRISPR Journal, 6(2), 116-126 (2023).

Programming the Cellular Uptake of Protein-Based Viromimetic Nanoparticles for Enhanced Delivery.

D.S. Moreno-Gutierrez, X. del Toro-Ríos, N.J. Martinez-Sulvaran, M.B. Perez-Altamirano, A. Hernandez-Garcia. Biomacromolecules, 24(4), 1563-1573 (2023).

Extending resolution within a single imaging frame.

E. Torres-García, R. Pinto-Cámara, A. Linares, D. Martínez, V. Abonza, E. Brito-Alarcón, C. Calcines-Cruz, E.G. Valdés Galindo, D. Torres, M. Jabloñski, H.H. Torres-Martínez, J.L. Martínez, H.O. Hernández, J.P. Ocelotl-Oviedo, Y. Garcés, M. Barchi, R. D’Antuono, A. Boskovic, J.G. Dubrovsky, A. Darszon, M.G. Buffone, R. Rodríguez-Morales, J.M. Rendon-Mancha, C.D. Wood, A. Hernandez-Garcia, D. Krapf, A.H. Crevenna, A. Guerrero. Nature Communications, 13(1), 7452 (2022).

A kinetic model for the impact of packaging signal mimics on genome encapsulation.

R. de Bruijn, P.C.M. Wielstra, C. Calcines-Cruz, T. van Waveren, A. Hernandez-Garcia, P. van der Schoot. Biophysical Journal, 121(13), 2583-2599 (2022).

Diastereomeric Separation of Chiral fac-Tricarbonyl(iminopyridine) Rhenium(I) Complexes and Their Cytotoxicity Studies: Approach toward an Action Mechanism against Glioblastoma.

G.A. Suárez-Ortiz, R. Hernández-Correa, M.D. Morales-Moreno, R.A. Toscano, M.T. Ramirez-Apan, A. Hernandez-Garcia, M. Amézquita-Valencia, D. Araiza-Olivera. Journal of Medicinal Chemistry, 65(13), 9281-9294 (2022).

Diagnostics of COVID–19 Based on CRISPR–Cas Coupled to Isothermal Amplification: A Comparative Analysis and Update.

A. Hernandez-Garcia*, M.D. Morales-Moreno, E.G. Valdés-Galindo, E.P. Jiménez-Nieto, A. Quezada. Diagnostics, 12(6), 1434 (2022).

An artificial virus-like triblock protein shows low in vivo humoral immune response and high stability.

D.S. Moreno-Gutierrez, J. Cepeda-Cervantes, L. Vaca, A. Hernandez-Garcia*. Materials Science & Engineering C, 129, 112348 (2021).

Strategies to Build Hybrid Protein–DNA Nanostructures.

A. Hernandez-Garcia*. Nanomaterials, 11(5), 1332 (2021).

CRISPR-guided programmable self-assembly of artificial virus-like nucleocapsids.

C. Calcines-Cruz, I.J. Finkelstein, A. Hernandez-Garcia*. Nano Letters, 21(7), 2752-2757 (2021).

Delivery of Antisense DNA into Pathogenic Parasite Trypanosoma cruzi Using Virus-Like Protein-Based Nanoparticles.

R.E. Cárdenas-Guerra, D.S. Moreno-Gutierrez, O.J. Vargas-Dorantes, B. Espinoza, A. Hernandez-Garcia*. Nucleic Acid Therapeutics, 30(6), 392-401 (2020).

Programmable polypeptide and nucleic acid nanoparticles.

A. Hernandez-Garcia, S.I. Stupp, Z. Álvarez-Pinto. U.S. Patent No. 10407469B2 (2019).

Template‐free Self‐Assembly of Artificial De Novo Viral Coat Proteins into Nanorods: Effects of Sequence, Concentration, and Temperature.

E. Cazares Vargas, M. Cohen Stuart, R. de Vries, A. Hernandez-Garcia*. Chemistry–A European Journal. 25(47), 11058-11065 (2019).

Nature of Amorphous Hydrophilic Block Affects Self-Assembly of an Artificial Viral Coat Polypeptide.

L. Willems, L. van Westerveld, S. Roberts, I. Weitzhandler, C. Calcines Cruz, A. Hernandez-Garcia, A. Chilkoti, E. Mastrobattista, J. van der Oost, R. de Vries. Biomacromolecules. 20(10), 3641-3647 (2019).

Real-Time Assembly of Viruslike Nucleocapsids Elucidated at the Single-Particle Level.

M. Marchetti, D. Kamsma, E. Cazares Vargas, A. Hernandez-Garcia, P. van der Schoot, R. de Vries, G.J.L. Wuite, W.H Roos. Nano letters 19(8), 5746-5753 (2019).

Peptide–siRNA Supramolecular Particles for Neural Cell Transfection.

A. Hernandez‐Garcia, Z. Álvarez, D. Simkin, A. Madhan, E. Pariset, F. Tantakitti, O.J. Vargas‐Dorantes, S.S. Lee, E. Kiskinis, S.I. Stupp. Advanced Science. 6(3): 1801458 (2019).

Protein-coated dsDNA nanostars with high structural rigidity and high enzymatic and thermal stability.

E.G. Sanchez-Rueda, E. Rodriguez-Cristobal, C.L. Moctezuma-González, A. Hernandez-Garcia*. Nanoscale. 11, 18604-18611 (2019).

Force and Scale Dependence of the Elasticity of Self-Assembled DNA Bottle Brushes.

M. Santos Rocha, I.M. Storm, R.F. Bazoni, É. Ramos, A. Hernandez-Garcia, M.A. Cohen Stuart, F. Leermakers, R. de Vries. Macromolecules. 51(1), 204-212 (2018).

Templated co-assembly into nanorods of polyanions and artificial virus capsid proteins.

A. Hernandez-Garcia*, M.A. Cohen Stuart, R. de Vries. Soft Matter. 14, 132-139 (2018).

Virus-Like Particles of mRNA with Artificial Minimal Coat Proteins: Particle Formation, Stability, and Transfection Efficiency.

S. Jekhmane, R. de Haas, O.P. da Silva Filho, A.H. van Asbeck, M.E. Favretto, A. Hernandez-Garcia, R. Brock, R. de Vries. Nucleic Acid Therapeutics. 27(3), 159-167 (2017).

Engineered Diblock Polypeptides Improve DNA and Gold Solubility during Molecular Assembly.

N.A. Estrich, A. Hernandez-Garcia, R. de Vries, T.H. LaBean. ACS Nano. 11 (1), 831-842 (2017).

Precise Coating of a Wide Range of DNA Templates by a Protein Polymer with a DNA Binding Domain.

A. Hernandez-Garcia*, N.A. Estrich, M.T.W. Werten, J. Van der Maarel, T.H. LaBean, F.A. de Wolf, M.A.C. Stuart, R. de Vries. ACS Nano. 11 (1), 144–152 (2017).

Supramolecular Virus-Like Nanorods by Coassembly of a Triblock Polypeptide and Reversible Coordination Polymers.

A. Hernandez-Garcia*, A.H. Velders, M.A.C. Stuart, R. de Vries, J.W.M. van Lent, J. Wang. Chemistry – A European Journal. 23(2) 239-243 (2016).

Self-Assembly Dynamics of Linear Virus-Like Particles: Theory and Experiment.

M. Punter, A. Hernandez-Garcia, D.J. Kraft, P. van der Schoot, R. de Vries. Journal of Physical Chemistry B, 120 (26), 6286–6297 (2016). Factor de Impacto 2.99

Liquid Crystals of Self-Assembled DNA Bottlebrushes.

I.M. Storm, M. Kornreich, A. Hernandez-Garcia, I.K Voets, R. Beck, M.A.C. Stuart, F.A.M. Leermakers, R. de Vries. Journal of Physical Chemistry B, 119 (10), 4084-4092 (2015).

Design and Self Assembly of Simple Coat Proteins for Artificial Viruses.

A. Hernandez-Garcia*, D.J. Kraft, A.F.J. Janssen, P.H.H. Bomans, N.A.J.M. Sommerdijk, D.M.E. Thies-Weesie, M.E. Favretto, R. Brock, F.A. de Wolf, M.W.T. Werten, P. van der Schoot, M.C. Stuart, R. de Vries. Nature Nanotechnology, 9, 698–702 (2014).

Amplified Stretch of Bottlebrush-Coated DNA in Nanofluidic Channels. 

Zhang, A. Hernandez-Garcia, K. Jiang, Z. Gong, D. Guttula, S.Y. Ng, P.P. Malar, J.A. van Kan, L. Dai, P.S. Doyle, R. de Vries, J.R.C. van der Maarel. Nucleic Acids Research, 41 (20), e189 (2013).

Pearl-Necklace Complexes of Flexible Polyanions with Neutral-Cationic Diblock Copolymers.

M.D. Golinska, F.A. de Wolf, M.C. Stuart, A. Hernandez-Garcia, R. de Vries. Soft Matter, 9 (28), 3491-3501 (2013).

Coating of Single DNA Molecules by Genetically Engineered Protein Diblock Copolymers.

A. Hernandez‐Garcia*, M.W.T. Werten, M.C. Stuart, F.A. de Wolf, R. de Vries. Small, 8 (22), 3491-3501 (2012).

In Vivo Protein Stabilization Based on Fragment Complementation and a Split GFP System.

S. Lindman, A. Hernandez-Garcia, O. Szczepankiewicz, B. Frohm, S. Linse. Proc. Natl. Acad. Sci. USA. 107, 19826-31 (2010).