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Research Interest in BMDM Lab.
Research Interest in BMDM Lab.
Drug delivery, Gene delivery
Polymer design and Synthesis
Immune regulation & Anti-PEG responses
Inorganic Cluster & Nanoparticle Synthesis
Adhesive Materials and Thier Application
Nanomaterial Surface Modification for Immune Regulation and Drug delivery
Nanomaterial Surface Modification for Immune Regulation and Drug delivery
Nanoparticles, due to their size similar to viruses, inevitably interact with the immune system. This presents an opportunity to either evade or enhance immune responses through engineering the surface polymer structure of the particles.
By evading immune responses, effective drug delivery can be achieved. Conversely, by enhancing immune responses or delivering drugs to immune cells, the immune system can be supported. The surface characteristics of the nanoparticles, such as size and shape, have an absolute influence on their interaction with the immune system, making their design and regulation crucial in research.
Modulating Nano-bio Interaction for Biomedical Application
Modulating Nano-bio Interaction for Biomedical Application
When nanomaterials enter the body, they interact with surrounding biomolecules, cells, and tissues.
By utilizing the adsorption properties of nanoparticles on their surface, they can be used as adhesives such as tissue or cell adhesives, and this can be applied in tissue engineering.
Additionally, molecular exchange at the molecular level occurs on the surface of nanoparticles and inorganic clusters, which can be utilized for drug delivery, colorants, imaging, and more. Our laboratory is conducting research on various biomedical applications using nanoparticles based on functional inorganic materials.
We synthesize nanoparticles with desired functionalities based on an understanding of the interactions between the biological environment and materials, and apply them to various biomedical fields.
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