The synthesis of organic compounds sustainably is an essential requirement for many chemical industries. In this context, our group focused on the development of novel synthetic methods sustainably. The objective could be realized by considering the following aspects of the new synthetic method developments. 

• Earth-abundant 3d metal catalysts

• Green and bio-mass derived solvents

• Green energy resources 

• Effective utilization of green and renewable feedstocks

• Efficient Recycling of Catalysts and Solvents

• Adapting new techniques for organic synthesis

• Effective utilization of computational methods to predict the reaction possibilities 

Inventing novel transformations is the key to achieve sustainability in chemical synthesis. In this context, developing alternative methods to conventional multi-step functional group transformation is an ideal strategy to attain high-efficiency organic synthesis. Thus, our group focused on the functionalization of C-H bonds into various functional groups and complex natural scaffolds. This strategy significantly enhances the atom-economy of the overall transformations. Our focus also extends to develop new catalysts and reaction systems for C-C, C-O, C-S, C-N, and C-F activations.

Synthesis of organic compounds in an atom-economic and environment-friendly way is an essential and challenging task in industrial and academic research. Transition metal catalysis has advanced synthetic strategies over the last three decades through higher reactivity, regio- and stereoselectivities, excellent functional group tolerance, and improved atom efficiency. On the other hand, these transformations often require very high reaction temperature, hazardous reaction conditions, (super)stoichiometric oxidants or reductants, and demanding traditional and sensitive reagents. In recent years, photoredox catalysis has received significant attention in response to topical interest in renewable energy and green chemistry. This strategy allows accessing reactive intermediates under mild reaction conditions (often at room temperature) from less functionalized and/or abundant feedstocks. In this context, our group is interested in the merger of transition metal catalysis and photocatalysis, which could provide a versatile platform for developing new, highly enabling synthetic methodologies.

• Renewable Energy

• No stoichiometric oxidant and reductant

• Mild reaction conditions

• New reactivity and selectivity

• Novel mechanism

Molecular synthesis in a sustainable manner is a prime area of research in both academia and industry. Thus, electrocatalysis uses electrons as a green reagent to produce useful products, significantly reducing the use of hazardous oxidizing or reducing reagents and ensuring high levels of sustainability. The recent emergence of metallaelectro-catalysis provides an opportunity to explore several oxidative transformations in the absence of toxic and expensive metal-based oxidants. Furthermore, several reported transformations follow a distinct mechanism under electrochemical conditions.

• Electrochemical organic synthesis is a sustainable, eco-friendly, environmentally safe method for C-C and C-heteroatom bond formations via cross-couplings and C-H bond activation.

• A controlled reaction pattern with switchable on-off electrochemical methods can be possible.

• Electrocatalysis ensures high levels of atom-, step- redox-, and resource economy of the overall transformation.

• Avoiding toxic oxidants and reductants is achievable; stoichiometric usage is completely reduced with the electrochemical approach.

• Electrochemical synthesis empowers the improvement in terms of rate, yield, and time consumption

• Enables effective scaling-up and increased turnover of catalyst to prevent overloading.

Mechanochemical organic synthesis represents a transformative approach to sustainable chemistry, where chemical reactions are driven by mechanical force rather than conventional thermal activation in bulk solvents. By employing ball milling or grinding techniques, we enable solvent-free or minimal-solvent transformations that significantly reduce chemical waste, energy consumption, and environmental footprint.

Our research focuses on developing mechanochemical strategies for transition metal-catalyzed C–H functionalization, cross-coupling, and heterocycle synthesis under solid-state conditions. We aim to demonstrate that mechanochemistry is not merely an alternative reaction medium, but a platform capable of unlocking new reactivity, enhanced selectivity, and improved efficiency compared to traditional solution-phase methods.

Key objectives of our mechanochemical research include:

• Development of solvent-free catalytic protocols

• Exploration of mechanochemical C–H activation strategies

• Comparative green metrics analysis versus solution-phase reactions

• Scalable and energy-efficient synthetic methodologies

• Discovery of unique solid-state reaction pathways

By integrating mechanochemistry with catalysis, photochemistry, and sustainable reaction design, we seek to establish environmentally benign and industrially relevant synthetic platforms for modern organic synthesis.