Publications

List of selected publications

1.    Holter JC, Chang CW, Avendano A, Garg AA, Verma AK, Charan M, Ahirwar DK*, Ganju RK*, Song JW*. Fibroblast-derived CXCL12 increases vascular permeability in a 3-D microfluidic model independent of extracellular matrix contractility. Frontiers in Bioscience & Bioengineering, 2022 [In Press],      * Equal correspondence                                                                   

2.    Ahirwar DK*, Pang B, Charan M, Misri S, Mishra S, Kaul WK, Sassi S, Gadepalli VS, Siddiqui J, Miles WO, Ganju RK*. Slit2/Robo1 signaling inhibits small cell lung cancer by targeting beta-Catenin signaling in tumor cells and macrophages. Molecular Oncology 2022 [In Press]. * Equal correspondence.                                                  

3. Swati Misri, Kirti Kaul, Sanjay Mishra, Manish Charan, Ajeet Verma, Martin P Barr, Dinesh K Ahirwar*, Ramesh K Ganju*. Cannabidiol Inhibits Tumorigenesis in Cisplatin-Resistant Non-Small Cell Lung Cancer via TRPV2. Cancers (Basel) 2022 Feb 24;14(5):1181. * Equal correspondence                                                                                     

4.     Mishra S, Charan M, Shukla RK, Agarwal P, Misri S, Verma AK, Ahirwar DK, Siddiqui J, Kaul K, Sahu N, Vyas K, Garg AA, Khan A, Miles WO, Song JW, Bhutani N, Ganju RK. cPLA2 blockade attenuates S100A7-mediated breast tumorigenicity by inhibiting the immunosuppressive tumor microenvironment. J Exp Clin Cancer Res. 2022 Feb 8;41(1):54.

5.   Kirti Kaul, Martin Benej, Sanjay Mishra, Dinesh Ahirwar, Marshleen Yadav, Kristin Stanford, Naduparambil Jacob, Nicholas Denko, and Ramesh K, Ganju. Slit2-mediated metabolic reprogramming in bone marrow derived macrophages enhances anti-tumor immunity. Frontiers in Immunology, 2021 Oct 28;12:753477.

6.       Ahirwar DK*, Charan M, Mishra S, Verma AK, Shilo K, Ramaswamy B, Ganju RK*. Slit2 inhibits breast cancer metastasis by activating M1-like phagocytic and anti-fibrotic macrophages. Cancer Research 2021; 81(20): 5255-5267.       * Equal corresponding authors.  

7.       Wilkie T, Verma AK, Zhao H, Charan M, Ahirwar DK, Kant S, Pancholi V, Mishra S, Ganju RK. Lipopolysaccharide from the commensal microbiota of the breast enhances cancer growth: role of S100A7 and TLR4. Molecular Oncology. 2021. (In Press).          

8.    Charan M, Das S, Mishra S, Chatterjee N, Varikuti S, Kaul K, Misri S, Ahirwar DK, Satoskar AR, Ganju RK. Macrophage migration inhibitory factor inhibition as a novel therapeutic approach against triple-negative breast cancer. Cell Death & Disease. 2020; 11(9): 774.                                                                               

9.    Varikuti S, Singh B, Volpedo G, Ahirwar DK, Jha BK, Saljoughian N, Viana AG, Verma C, Hamza O, Halsey G, Holcomb EA, Maryala RJ, Oghumu S, Ganju RK, Satoskar AR. Ibrutinib treatment inhibits breast cancer progression and metastasis by inducing conversion of myeloid-derived suppressor cells to dendritic cells. British Journal of Cancer. 2020;122(7): 1005-1013.                                                                                                          

10.    Garg AA, Jones TH, Moss SM, Mishra S, Kaul K, Ahirwar DK, Ferree J, Kumar P, Subramaniam D, Ganju RK, Subramaniam VV, Song JW. Electromagnetic fields alter the motility of metastatic breast cancer cells. Communication Biology. 2019; 2: 303.     

11.    Ahirwar DK, Nasser MW, Ouseph M, Elbaz M, Cuitiño M, Kladney R, Ramaswamy B, Zhang X, Ostrowski M, Leone G, Ganju RK, Fibroblast-Derived CXCL12 Promotes Breast Cancer Metastasis by Facilitating Tumor Cell Intravasation. Oncogene, 2018; 37(32): 4428-4442.

12.    Elbaz M, Ahirwar DK, Xiaoli Z, Zhou X, Lustberg M, Nasser MW, Shilo K, Ganju RK. TRPV2 is a novel biomarker and therapeutic target in triple-negative breast cancer. Oncotarget. 2016; 9(71):33459.                                                                                   

13.    Mishra S, Ahirwar DK, Ganju RK. Psoriasin (S100A7): a novel mediator of angiogenesis. British Journal of Dermatology, 2016;175(6): 1141-1142.

14.    Ahirwar DK, Nasser MW, Jones TH, Sequin EK, West JD, Henthorne TL, Javor J, Kaushik AM, Ganju RK, Subramaniam VV. Non-contact method for directing electrotaxis. Scientific Reports. 2015 Jun 9;5:11005.                                                                   

15.    Nasser MW, Elbaz M, Ahirwar DK, Ganju RK. Conditioning solid tumor microenvironment through inflammatory chemokines and S100 family proteins. Cancer Letters, 2015; 365(1): 11-22.                                                                                                 

16.    Nasser MW, Wani NA, Ahirwar DK, Powell CA, Ravi J, Elbaz M, Zhao H, Padilla L, Zhang X, Shilo K, Ostrowski M, Shapiro C, Carson WE 3rd, Ganju RK. RAGE mediates S100A7-induced breast cancer growth and metastasis by modulating the tumor microenvironment. Cancer Research, 2015; 75(6): 974-85. 

17.    Ahirwar DK, Mandhani A, Dharaskar A, Kesarwani P, Mittal RD. Association of tumor nacrosis factor-alpha (T-1031C, C-863A, and C-857T) polymorphisms with bladder cancer susceptibility and outcome after BCG immunotherapy. British Journal of Urology International.  2009; 104(6): 867-73.

18.    Mittal RD, Singh R, Manchanda PK, Ahirwar DK, Gangwar R, Kesarwani P, Mandhani A. XRCC1 Codon 399 Mutant Allele: A Risk Factor for Recurrence of Urothelial Bladder Carcinoma in Patients on BCG Immunotherapy. Cancer Biology and Therapy. 2008; 7(5): 645-50.